Báo cáo y học: "Sequences to systems" doc

... stimuli. Regev’s strategy was to monitor the complete transcriptional response to each stimulus, identify the key regulators (transcription factors, chromatin-modifying complexes and RNA- binding ... regulators across these critical cellular pathways, but also revealed the cooption of cell-cycle circuits in the antiviral response. is approach to systems biology could also be appl...

Ngày tải lên: 09/08/2014, 20:21

... infection? Commentary on the meta-analysis by Bongartz et al. Arthritis Res Ther 2006, 8:111. Letter Response to commentary by Dixon and Silman on the systematic review and meta-analysis by Bongartz et ... dose-effect criterion for causality. The low risk in the comparison group may be real, the result of chance, or due to an as yet unclear systematic design or analysis flaw of all inclu...

Ngày tải lên: 09/08/2014, 08:22

... significantly during 2 years of follow up. However, because the correlation between anti-MCV levels and parameters of disease activity was very low, it is not useful to measure anti-MCV levels to monitor ... patients Antibody Sensitivity (%; 95% CI) Specificity (%; 95% CI) PPV (%) Anti-CCP2 level ≥ 25 U/ml 55.3 (46.1 to 64.2) 92.1 (77.5 to 97.9) 95.8 Anti-MCV level ≥ 20 U/ml 59.3 (50....

Ngày tải lên: 09/08/2014, 10:22

... the necessary infrastructure was so rare that many of them had to lug a special projector with them, like explorers toting vital supplies into the uncharted wilderness. I, along with many of my colleagues, ... is due to the inherent superiority of their method of showing visual aids. They would further claim that our productivity has been greatly increased by its intrinsic greater efficie...

Ngày tải lên: 09/08/2014, 20:20

... declare that they have no competing interests. They did not receive any grants nor do they have any vested interests in the equipment described. References 1. Akcali DT, Ozkose Z, Yardim S: Do we ... Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Journal of Brachial Plexus and Peripheral Nerve Injury 2008...

Ngày tải lên: 10/08/2014, 10:20

... inflammatory mediators, increase of cytokines and free radicals probably due to hypoxic injury of the atelectatic lung may be involved in pathogenesis of RPE [6,8-11]. More than one century ago, ... shown that; hypoxia-reoxygenation injury of one lung may cause acute respiratory distress syndrome (ARDS) in the other, along with systemic multi-organ injuries [15]. According to a study it i...

Ngày tải lên: 10/08/2014, 10:20

... hich shed their cytotoxic enzymes, cytokines, and oxygen free radicals on the endothelium, leading finally to an extensive tissue Apostolakis et al. Journal of Cardiothoracic Surgery 2010, 5:1 http://www.cardiothoracicsurgery.org/content/5/1/1 Page ... cardiopulmonary bypass circuits on in vitro oxygen free radical production during coronary bypass surgery. Artif Organs 1996, 20:1008-16. 34...

Ngày tải lên: 10/08/2014, 10:20

... linearity, sensitivity, specificity, and reproducibility of the multiplex real-time assays. They also served as external positive controls (EPCs) in the multiplex real-time PCR and RT-PCR assays. To ... immune function, exposure to tox- ins, chemicals and pesticides, stress, hypotension, abnor- mal lymphocyte levels, and neuroendocrine dysfunction. However, the precise underlying mechanis...

Ngày tải lên: 12/08/2014, 01:21

... biological therapy should be added to disease- modifying anti-rheumatic drug (DMARD) therapy [5-8]. Additionally to this add-on strategy, applying tight con- trol increases the ability to induce remission ... was to study the association between time -to- remission and sustainability of remission in a cohort of early RA patients treated according to daily practice. Methods: For thi...

Ngày tải lên: 12/08/2014, 14:21

Ngày tải lên: 12/08/2014, 18:21