Báo cáo y học: "Microbial signaling and systems biology" ppsx

... interesting and diverse sympo- sium during a major microbiology conference helped disseminate systems- biology ideas amongst researchers in virology, bacteriology, mycology and parasitology. While ... phagocytosis and development. John McKinney (Swiss Federal institute of Technology, Lausanne, Switzerland) described a powerful combina- tion of microscopy and microfluidics to tempo...

Ngày tải lên: 09/08/2014, 20:21

... extend the work of Rosen and Casti who discuss category theory with regards to systems biology and manufacturing systems, respectively. Results: We describe anticipatory systems, or long-range feed-forward ... anticipatory systems and contain within themselves mod- els of the system and the system controller. The phrase anticipatory system, by itself, seems to ignore causality....

Ngày tải lên: 13/08/2014, 16:20

... auspices of the charity Cancer Research UK looked at cell -signaling pathways in relation to cancer and how they may point to new therapeutic approaches. Signaling pathways and signaling mechanisms The ... Biology 2007, 8:310 Meeting report Cell signaling and cancer Eleni Bazigou* and Charalampos Rallis † Addresses: *Lymphatic Development Laboratory and † Developmental Genet...

Ngày tải lên: 14/08/2014, 07:22

... and Vishwanath R Iyer Address: Section of Molecular Genetics and Microbiology, Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, University of Texas at Austin, ... pathway, c- Myc, and the PI3K pathway [18]. We observed altered expres- sion of regulatory factors in the RAS-MAPK pathway and the PI3K pathway, such as YWHAG (14-3-3- gamma) [19...

Ngày tải lên: 14/08/2014, 16:21

... double-strand breaks. Abundant acetylation of lysine 56 (K56) of histone H3 is found predominantly in newly syn- thesized histones that are incorporated into nucleosomes during S phase of the cell cycle, ... facilitate transcription from cryptic promoters. Mellor also introduced the idea that many of the epigenetic marks analyzed by researchers are dynamic, as illustrated by data from the MET...

Ngày tải lên: 14/08/2014, 16:21

... conceptually much simpler. The future is likely to see many more mechanistically under- stood models of actual biological systems that rely on computational methods in systems biology for their construction. ... mmooddeellss iinn ssyysstteemmss bbiioollooggyy Laurence Loewe* and Jane Hillston † Addresses: *Centre for Systems Biology at Edinburgh, School of Biological Sciences, The Uni...

Ngày tải lên: 14/08/2014, 21:20

... Factor and Signal Trans- duction Symposium, Ames, USA, 11-14 June 2009. This year’s annual growth factor and signal transduction symposium held at Iowa State University focused on systems- biology ... regulation and systems- level analysis and modeling of the responses of biological systems to perturbations. A few of the highlights of the meeting in these fields are reported he...

Ngày tải lên: 14/08/2014, 21:20

... matrilysin is induced in response to airway injury and is markedly upregulated in CF, and that its catalytic activity is essential for the repair of airway epithelial wounds. 40. López-Boado YS, ... MT2, MT3, and MT5) have trans- membrane and cytosolic domains, whereas MT4-MMP and leukolysin (MT6-MMP) also have C-terminal hydropho- bic extensions that act as a glycosylphosphatidylin...

Ngày tải lên: 12/08/2014, 18:20

... implicated in synaptic plasticity, and play a role in repair of the nervous system following injury [30-32]. Cancer Eph receptor and ephrin ligand signaling is known to play a role in many types of ... preaxial polydactyly was still present. Despite evidence for the involvement of the sonic hedgehog pathway in polydactyly, no evidence was found for a role for this pathway in the...

Ngày tải lên: 08/08/2014, 17:20

... this disease, which includes pathophysiology and joint stability including biomechanics. The balance between anabolic morphogens and growth factors and catabolic cytokines is at the crux of the problem of ... kinases phosphorylate the cytosolic Smads 2 and 3, which are also referred to as R-Smads and receptor- activated Smads. Phosphorylation of Smads 2 and 3 results in a conforma...

Ngày tải lên: 09/08/2014, 07:20