Báo cáo y học: " Membrane traffic in the post-genomic era " potx

... accumulating evi dence for regulation in the converse direction - of the membrane machinery by signaling - at multiple stages of both the membrane- biosynthetic and endocytic pathways [7,8]. Analysis ... endocytic pathways in mammalian cells e main new advance introduced in the study of Collinet et al. is automated phenotyping of the endocytic pathway, using quantitat...

Ngày tải lên: 09/08/2014, 20:21

... Angiotensin Converting Enzyme CYP = Cytochrome P450 + Not all agents are appropriate for monotherapy. Inclusion in this table does not necessarily imply efficacy. * Currently FDA approved for use in ... primarily in patients with seizure disorders. Carbamazepine-induced increase in total cholesterol is primarily due to an increase in HDL [34]. This occurs during the initial weeks...

Ngày tải lên: 25/10/2012, 10:51

... continuously being identified, and these polymorphisms may play a pivotal role in sporadic carcinogenesis. A growing body of literature, including observations of inter-individual differences in ... examined an interaction between the T19007C polymorphism and cigarette smoking. When stratified by smoking status, the interaction between smoking and the polymorphism was not sta-...

Ngày tải lên: 31/10/2012, 14:59

... proposed to be the start of the protein coding domain. Sequence analysis of the 3¢ end cDNA revealed that there is a polyadenylation signal upstream of the poly(A). Analysis of the primary structure ... secondary pathways can occur: adenylate cyclase catalyses the formation of cAMP, whereas phospholipase C hydrolyses membrane phospha- tidylinositol, liberating inositol 1,4,5-tri...

Ngày tải lên: 17/03/2014, 23:20

... attention is paid in the general medical literature. In the most recently pub- lished highly regarded geriatric text, rhinitis is not included in the index whereas rhinophyma is [1]. The number of ... mucous-secreting glands; the effectiveness of the mucociliary system is reduced, resulting in symptoms of nasal stuffiness. In addition, a decrease in nasal blood flow le...

Ngày tải lên: 08/08/2014, 21:20

... patients using the RPAS and the AIMS, the second using the PANSS and the EPSE and the third using the BARS. Information from the patient's his- tory, concerning social-demographic and clinical ... general psychopathol- ogy symptoms, estimated by both the PANSS and the BPRS. We did not find any studies exploring the the relationship between physical anhedonia and mot...

Ngày tải lên: 08/08/2014, 21:20

... [12]. Joint tissue engineering: clinical applications The first entry for the key word ‘tissue engineering’, also termed ‘regenerative medicine’, in the National Center for Biotechnology Information ... proinflam- matory stimuli [10,73]. For the in vitro analysis of cartilage destruction in RA, interactions between (a) chondrocytes as a single cell type entirely conducting the...

Ngày tải lên: 09/08/2014, 01:22

... differences in labelling using the average values of seven housekeeping genes: β 2 - microglobulin, β -actin, cyclophilin A, glyceraldehyde-3- phosphate dehydrogenase, HLA-A 0201 heavy chain, human hypoxanthine ... are another cell type expressing CXCR5 in the synovium. There have been several reports of endothelial cells in the RA synovium expressing chemokine receptors, includ...

Ngày tải lên: 09/08/2014, 06:22

... early bacterial infection in the joint. Somatic mutations in mitochondrial peptides displayed by MHCs may be recognized as non-self, furthering the destructive immune infiltration of the RA joint. ... may also play a causative role in RA. Competing interests The author(s) declare that they have no competing interests. Authors' contributions TD participated in the design...

Ngày tải lên: 09/08/2014, 06:23

... in other domains [22]. The role of leisure in maintaining or restoring psychological well- being in the presence of arthritis pain warrants further study. Psychosocial approaches to managing arthritis ... typically a series of six weekly group sessions led by trained lay leaders, which specifically targets self efficacy skills in the manage- ment of arthritis symptoms, including...

Ngày tải lên: 09/08/2014, 08:23