Báo cáo y học: "Flux balance analysis accounting for metabolite dilution" docx

... 2-octapre- nyl-3-methyl-6-methoxy-1,4-benzoquinol; 2omph, 2-octaprenyl-6- methoxyphenol; 2oph, 2-octaprenylphenol; 3ophb, 3-octaprenyl-4- hydroxybenzoate; ahcys, s-adenosyl-l-homocysteine; amet, ... it is used only under some environments). 2ohph, 2-octaprenyl-6-hydroxyphenol; 2ombzl, 2-octaprenyl-6-methoxy-1,4-benzoquinol; 2omhmbl, 2-octaprenyl-3- methyl-5-hydroxy-6-methoxy-1,4-benzoquinol...

Ngày tải lên: 09/08/2014, 20:21

... predictive of efficacy. Unfortunately, they entail the use of one PK-derived value such as AUC or Cmax and may thus lead to biased efficiency information when the variability is large. The aim ... efficiency function intro- duced above, two PK profiles are ascertained as efficiency- equivalent, i.e.PK 1 ⇔ PK 2 in efficiency, if and only if they verify the condition: More precisely, for co...

Ngày tải lên: 13/08/2014, 16:21

... web page, downloadable for further analysis. Rationale Microarray technology is now more accessible than ever before. Thanks to its unrivaled capability to carry out a very large number of parallel ... in situ synthesis creates morphologically uniform array elements, which, to a large degree, obviates the need for spot filtering, an imperative procedure for PCR microarray data analys...

Ngày tải lên: 14/08/2014, 07:21

... computer. Still, for most applications, image cytometry (automated cell image analysis) is strongly preferable to anal- ysis by eye. In fact, in some cases image cytometry is abso- lutely required ... the many steps typically involved in image analysis, many of which are not easily transferable from one project to another (for example, image formatting, combining several image analysis...

Ngày tải lên: 14/08/2014, 17:22

... persistent wheezing beyond infancy and early childhood usually have a family history of asthma and allergies and present with allergic symptoms very early in life [2,3]. Determinants in early life for asthma ... induce BA in a previously complete healthy baby with a complete negative family history for BA or allergy [4]. Therefore, there are few truly justified recommendations for the p...

Ngày tải lên: 08/08/2014, 21:20

... platforms [5]. When perform- ing systems biology analyses, failure to account for this effect will lead to biased results. One simple, but extremely widely used, systems biology technique for ... reproduction in any medium, provided the original work is properly cited. Method Gene ontology analysis for RNA-seq: accounting for selection bias Matthew D Young, Matthew J Wakefield, Go...

Ngày tải lên: 09/08/2014, 20:21

... artery (LAD) by primary PCI were retrospectively enrolled in this study. Inclusion criteria were AMI caused by LAD oc- clusion (type I, ESC) and coronary artery disease af- fecting only 1 or ... echocardiography allowing a three-myocardial layer-specific analysis of deformation pa- rameters. Eur J Echocardiogr 2009; 10(2): 303-308. 9. Becker M, Hoffmann R, Kuhl HP, et al. Analysis of...

Ngày tải lên: 25/10/2012, 11:15

... microarray analysis Data analyses were performed using the GeneChip Expression Analysis Software (version 3.2, Affymetrix). First, single array analysis was performed [11] to calculate for each ... One-Cycle cDNA Synthesis Kit (Affymetrix). Fifteen micrograms of labeled and fragmented cRNA were subsequently hybridized to a Human Genome U133 plus 2.0 microarray (Affymetrix). Af...

Ngày tải lên: 31/10/2012, 15:28

... nor there do any test that was totally specific in this respect. Sensitivities ranged from 64% for assay of Abs against teichoic acid to 72% for assays of antibody to peptidoglycan and α-toxin. ... statistical analysis, David Griffith for photography and Dr. Fu-Shin Yu (Kresge Eye Institute) for his valuable critiques. Conflict of interest None declared. References 1. Lowy F...

Ngày tải lên: 02/11/2012, 11:08

... erythrocyte proteome: analysis by ion trap mass spectrometry. Mollecular und Cellular Proteomics 2004;3:501-509. 9. Tyan YC, Jong SB, Liao JD et al. Proteomic profiling of eryth- rocyte proteins by ... important key for under- standing the machinery of anucleate protein synthesis and its meaning in the pathophysiology of diseases. Acknowledgements This work was supported by the Deut...

Ngày tải lên: 03/11/2012, 10:58