Báo cáo y học: "proving draft assemblies by iterative mapping and assembly of short reads to eliminate gaps" docx

... markedly influenced by mutations in this region of the enzyme. Moreover, the bsubunit appears to influence the confor- mation and ion sensitivity of the sodium pump. If the b subunit of the sodium pump ... cooperativity of the a subunits described by Repke occurs only in the presence of Na + and K + [17]. The partial reactions of the Na + /K + -ATPas...

Ngày tải lên: 24/03/2014, 00:21

... frequency of the TNFRII 196R/ R genotype in the French Caucasian popu- lation and the suggested association between the TNFRII 196R allele and severity of RA [18], Fischer's exact test and Student's ... = 0.0012). TNFRII 196M/R genotypes, 196R allele frequencies and diagnosis of very early RA A total of 283 VErA patients were genotyped for...

Ngày tải lên: 09/08/2014, 06:23

... an anti-inflammatory type [26]. This relative deviation of the cytokine response, caused either by decreased Th1-type cytokines and/ or by enhanced Th2-type cytokines leading to the regression of an autoimmune ... anti-inflammatory cytokines over pro- inflammatory cytokines in response to Bhsp65 To test and compare the T cell proliferative and cytokine response...

Ngày tải lên: 09/08/2014, 10:20

... article NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating ... involved in osteoclastogenesisEffect of dehydroxymethylepoxyquinomicin on serum factors involved in osteoclastogenesis. Effec...

Ngày tải lên: 09/08/2014, 10:21

... these findings underscore the complexity of the rheumatic diseases and highlight the key role of epidemiological research in understanding these intriguing conditions. Competing interests The authors ... 0.27%). Together, these findings indi- cate that there is constancy in the epidemiologic charac- teristics of ankylosing spondylitis. The incidence and prevalence...

Ngày tải lên: 09/08/2014, 14:20

... staining pattern [2]. Despite the clearance of the AIT test by the South Korea Food and Drug Administration, to the best of our knowledge this test is not widely used as a screening method – neither ... AIT test represents a sensitive and reliable method for the detection of anti-Rib -P antibodies. A systematic study is mandatory to compare the sensitivity a...

Ngày tải lên: 09/08/2014, 14:22

... newly sequenced reads and any existing assembly by mapping, and then improves the assembly by localised assembly of reads at real gaps and regions that were previously unre- solved in the assembly; ... sequence reads against an initial assembly to identify those that can be used for gap-spanning; and local assembly of the selected subset of reads and...

Ngày tải lên: 09/08/2014, 20:21

... can coexist with oncocytoma. Renal oncocytomas are almost invariably benign and no cases of metastasis have been reported. Even when very large, they are generally well encapsulated and are rarely ... Tahmatzopoulos A: A rare case of renal oncocytoma associated with erythrocytosis: case report. BMC Urol 2006, 6:26. 4. Demos TC, Malone AJ Jr: Computed tomography of a...

Ngày tải lên: 11/08/2014, 11:22

... mycosis fungoides and only approximately 20 cases have been reported in the literature. Case presentation: We present a case of rapidly progressive mycosis fungoides in a 68-year-old Caucasian ... in the literature, appr oximately 20 cases of the bullous varia nt have been described. Case presentation A 68-year-old Caucasian man presented for evaluation of tw...

Ngày tải lên: 11/08/2014, 11:23

... indicate that CD39 + Tregs inhibit generation and differentiation of Th17 cells via a latency-associated peptide-dependent mechanism. Keywords: latency-associated peptide, malignant pleural effusion, ... doi:10.4049/jimmunol.0901881 doi:10.1186/1465-9921-12-77 Cite this article as: Ye et al.: CD39 + Regulatory T cells suppress generation and differentiation...

Ngày tải lên: 12/08/2014, 13:22

... potentially accelerate decision-making with regard to extubation; and to assess the safety and feasibility of our approach. Materials and method The intervention was carried out in a 14-bed medical/surgical ICU ... team members were recorded. Data on duration of MV, duration of ICU stay and the rate of reintubation were collected. Safety The MDT agreed that, in orde...

Ngày tải lên: 12/08/2014, 18:21

... immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus tar- gets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin ... prominent and replication appeared to abort. HIV-1 harboring in TERT-2 keratinocytes To study harbored HIV-1, TERT-2 monolayers were incu- bated with H...

Ngày tải lên: 13/08/2014, 05:21

... exist. This was a period when if one wished to learn what was being pub- lished, one had to reach for the weekly/monthly periodi- cals (that often meandered through the postal service sometimes, ... spotlights what IF in part does and does not convey. With that disclaimer, how is Retrovirology doing IF-wise as the journal enters its fourth year? Employing the algorithm that IF derives...

Ngày tải lên: 13/08/2014, 05:22

... 12 No 4 Research Health care costs, long-term survival, and quality of life following intensive care unit admission after cardiac arrest Jürgen Graf 1 , Cecile Mühlhoff 2 , Gordon S Doig 3 , ... increase and a decrease in health sta-tus index 5 years post -intensive care unit of 25% and 50%, respectively (bold solid line)Two-way sensitivity analysis de...

Ngày tải lên: 13/08/2014, 11:22

... 5:9 http://www.conflictandhealth.com/content/5/1/9 Page 5 of 11 RESEARCH Open Access Are there any changes in burden and management of communicable diseases in areas affected by Cyclone Nargis? Nyan Win Myint 1,2 , Jaranit Kaewkungwal 2* , ... one of theleadingcausesofmorbidityinthestudytownships. As shown in Figure 1, dyse ntery cases peaked sharply in...

Ngày tải lên: 13/08/2014, 15:21