Báo cáo y học: "The developmental expression dynamics of Drosophila melanogaster transcription factors" pptx
Báo cáo y học: "The developmental expression dynamics of Drosophila melanogaster transcription factors" pptx
... of both types of expression dataset is the granularity of both the sampling and the annota- tion. This implies that many of the co -expression clusters at the level of tissues may not actually ... article as: Adryan and Teichmann, The developmental expression dynamics of Drosophila melanogaster transcription factors Genome Biology 2010, 11:R40 Adryan and Teichmann...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challeng" ppt
... analysis of homologous genes of interest. However, neither the early phase events are easy to study in RA patients nor the microarray gene expression profiling of rats with AA has previously ... this important and timely study of the gene expression analysis in AA. In this study, we examined the gene expression profiles of the draining lymph node cells (LNC) of Mtb-immu...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: " The reticulons: a family of proteins with diverse function" pptx
... with the eukaryotic endomembrane system. Across phyla, the second hydrophobic region of the RHD is the most highly conserved, followed by the first hydrophobic region, with the carboxyl terminus ... proteins syntaxin 1, syntaxin 7, syntaxin 13 and VAMP2 [39]. Overexpression of a fragment of RTN1C increases the rate of exocytosis in PC12 cells. RTN1, RTN2, and RTN4 were all identified...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo Y học: The cold-active lipase of Pseudomonas fragi Heterologous expression, biochemical characterization and molecular modeling pdf
... peptide-independent pathway and calls for further investigation on this subject. Enzyme activity and specificity In the standard tricaprylin hydrolysis assay, rPFL displayed highest activity at 29 °C and ... wild type enzyme [30]. Interestingly, the enzyme lost most of its activity at 50 °C but retained about 60% of its specific activity at 10 °C (Table 1). Under the same conditions, the ac...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: " The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells" potx
... example, coronary artery is relaxed but pulmonary artery is con- tracted under hypoxic condition. Pulmonary vasocon- striction and PASMC proliferation may contribute to hypoxic pulmonary hypertension. ... Province (YJSCX2009- 223HLJ). Author details 1 Department of Pathophysiology, Qiqihar Medical University, Qiqihar 161006, PR China. 2 Department of Pathophysiology, Harbin Medical Univer...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns" ppsx
... Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands and 3 Department of Infectious Diseases and Immunology, Division of Virology, Faculty of Veterinary Medicine, ... and primary hepatocytes are difficult to main- tain in culture. Furthermore, primary hepatocytes rapidly lose detoxifying P450 isoenzymes. In addition, and because of the heter...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo Y học: The reductive hotspot hypothesis of mammalian aging Membrane metabolism magnifies mutant mitochondrial mischief pptx
... cells do not rely solely on glycolysis but also maintain an active TCA cycle, which entails a far greater rate of reduction (and hence reoxidation) of NAD. This may be possible only by reversing ... stress of superoxide to oxidative stress from hydroxyl and alkoxyl radicals. LDL oxidation may play a key role in atherosclerosis [41]; more generally, however, slightly oxidized LDL is read...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains pptx
... J.W. (1990) Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol. 185, 60–89. 20. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage ... membrane insertion of colicin A. Biochemistry 31, 7294–7300. 28. Kasahara, K., Watanabe, Y. , Yamamoto, T. & Sanai, Y. (1997) Association of Src family tyrosin...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking pdf
... hyperinsulinaemic hypoglycaemia of infancy is an hereditary disease char- acterized by inappropriately high levels of insulin release and hypoglycaemia in children at birth. It is hypothesized that deletion of the ... Potentially, this has clinical ramifications as a number of mutations in persistent hyperinsulinaemic hypoglycaemia of infancy [12] cluster in this domain of the prot...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: The C-terminal region of ammodytoxins is important but not sufficient for neurotoxicity pot
... Pungerc ˇ ar 2 1 Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia; 2 Department of Biochemistry and Molecular Biology and 3 Mass ... presynaptic membrane [6], after which they are presumably endocytosed. In the nerve cell, they may inhibit the recycling of synaptic vesicles by binding to certain targ...
Ngày tải lên: 31/03/2014, 08:20