Báo cáo y học: " The yin and yang of chromatin spatial organization" ppt
Báo cáo y học: " The yin and yang of chromatin spatial organization" ppt
... of chromatin may extend away from the core of the territory. (d) As G1 phase is established and nucleoli form, loops of NOR-containing chromatin co-associate with the other components of the ... nuclear lamina. These processes, along with others described in this article and many more, are likely be important in dynamically shaping the spatial environment and...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo khoa học: The Yin and Yang of protein folding doc
... identity of the polypeptide sequence [38,50]. The toxicity of different species and their role in the development of disease is currently being explored for different protein systems [39]. The Yin and ... initiate the amyloid cascade. Especially in age-related amyloidosis, this may lead to the accumulation of large quantities of partially folded proteins and the...
Ngày tải lên: 23/03/2014, 11:20
Báo cáo Y học: The processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus pot
... activity of RT specifically hydrolyses the RNA in these heteroduplexes. Finally, the plus-sense DNA strand is synthesized by copying of the minus-sense DNA strand by the DNA-dependent DNA polymerase (DDDP) ... Virology 259, 176–189]. In the p resent study, we have studied in vitro two features of the DNA polymerase activity of BLV RT, t he processivity of DNA synthesis a...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: "The use and abuse of commercial kits used to detect autoantibodies" ppsx
... high level of security, of scrutiny and of standardization, and under good labora- tory practices and quality control. Many of these compa- nies subscribe to and offer postmarketing quality assurance ... achieve the goal of improving the quality of patient care through the use of autoantibody testing and analysis. The matrix of manufacturing and application...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "The identification and characterization of a novel protein, c19orf10, in the synovium" docx
... properly cited. Abstract Joint inflammation and destruction have been linked to the deregulation of the highly synthetic fibroblast-like synoviocytes (FLSs), and much of our current understanding of ... fusion protein and the reac- tivity and specificity of the purified IgY were confirmed using GST-c19orf10 and a panel of unrelated His and GST fusion proteins. T...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "The promise and reality of personal genomics" pot
... likely to be easy to both genotype and sequence. The sensitivity of SNP and indel detection in repetitive or copy-number-variable regions will be lower. Finally, a non-trivial proportion of any ... (Solexa) [4] and Applied Biosystem’s SOLiD [5] systems - but no explicit comparison of the two versions has yet been published. Minireview The promise and reality of pers...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"
... synthesized by chondrocytes and FLS. These cytokines act in various ways in the pathogenesis of OA such as inhibition o f s y nth esi s o f type 2 (articular) cartilage and activation of catabolic ... design of the project and data analysis, and was primarily responsible for writing the manuscript. KVA contributed to the de- sign of the project, patient recruit...
Ngày tải lên: 25/10/2012, 11:40
Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx
... membrane and in addition to de novo synthesis, the plant enzyme is capable of catalysing the exchange of the inositol polar head for another inositol. Our data clearly show that the CDP-diacylglycerol-independent exchange ... capacity of PtdIns synthase, especially if the membranes used as a source of enzyme are rich in PtdIns. Another question is the reason why CMP stim...
Ngày tải lên: 22/02/2014, 04:20
Tài liệu Báo cáo Y học: Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL pptx
... regions adjacent to the beginning and the end of ybdQ and additional 20-nucleotide complementary to the template plasmid pKD13 carrying the kanamycin resistance (kan) gene. The resulted linear 1.4-kb ... of the stationary phase the rate of synthesis of heat-shock proteins increases considerably, but only transiently [2,18]. Similarly, we observed that the steady-st...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: The opgGIH and opgC genes of Rhodobacter sphaeroides form an operon that controls backbone synthesis and succinylation of osmoregulated periplasmic glucans pot
... coli,andwhat properties they confer in this context. The highly anionic character of OPGs synthesized by E. coli is due to the presence of phosphoglycerol and succinyl residues. Two genes mdoB and ... govern the synthesis of OPGs belonging to family I. In this paper, we describe the molecular and functional characterization of these genes, opgGIH, necessary for OPG backb...
Ngày tải lên: 17/03/2014, 17:20