Báo cáo y học: " PRDM9 points the zinc finger at meiotic recombination hotspots" potx
Báo cáo y học: " PRDM9 points the zinc finger at meiotic recombination hotspots" potx
... meiotic recombination by the same evolutionarily conserved process: DNA double- strand break (DSB) formation catalyzed by the topo- isomerase-like protein Spo11 (reviewed in [1]). us, all meiotic ... (the only known H3K4 methyltransferase activity in yeast) causes dramatic changes in the pattern of hotspot usage across the yeast genome [5], suggesting that H3K4me3 is an ev...
Ngày tải lên: 09/08/2014, 20:21
Tài liệu Báo cáo Y học: Systematic search for zinc-binding proteins in Escherichia coli potx
... i.e. catalytic and structural. The catalytic role specifies that zinc participates directly in enzyme catalysis, while structural zinc atoms are required for stabilization of proteins by supporting ... 1,6-bisphosphatase aldolase 4 GlyA Serine hydroxymethyltransferase 5 LpdA* (AtpA) Lipoamide dehydrogenase (F1 ATP synthase a subunit) 6 Ppa* (AhpC) Inorganic pyrophosphatase (alkyl hydrope...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo y học: "Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus" pps
... of hypersensitivity [5]. The major metabolic pathway for sulpham- ethoxazole is catalyzed by N-acetylation by N-acetyltrans- ferase 2 (NAT2). In the pathogenesis of hypersensitivity, the formation ... haplo- types exhibit the slow acetylator phenotype, whereas those who carry at least one wild-type haplotype exhibit the fast acetylator phenotype. In the present study we examined...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Use of the measure your medical outcome profile (MYMOP2) and W-BQ12 (Well-Being) outcomes measures to evaluate chiropractic treatment: an observational study"
... negative correlation with the GWB, a moderate negative correlation with the PWB and Energy scales and a positive moderate correlation with the Negative wellbeing scale. The Activity scale of the ... utilised for the study. Patients were invited to participate in the study if they were: over the age of 18 years; had no treatment from any health professional for their complaint...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"
... locations, as some clinics were dramatically affected and others were scarcely affected. They further noted that the quantitative data did not adequately capture the bravery of the AMPATH patients ... them to go on the roads and try to get [to clinic]. The risks to personal safety were seen to vary based on the fam- ilies' tribal affiliation, their location, and whether they...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"
... the main reason for treatment failure. When the idiopathic cyclic edema is not previously treating, the failure and early relapse rates of treat- ment for cellulite is more than 80%. Once the ... patients treated for Grade II and III cellulite were evaluated for idiopathic cyclic edema in a retrospective, quantitative and cross-sectional study. The study was carried out at th...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"
... showed the product at m/e 5958.9 calc. 5958.1, the trication at m/e 1986.5 and the tetracation at 1489. The dan- syl-tetrazine could be seen at m/e 875.7. 11. Ligation of the Pentamer II with the ... employed the Fmoc-strategy [21] in a fully automated peptide syn- thesizer A433 (Perkin Elmer). The synthesis was car- ried out on a 0.05 mmol Tenta Gel R Ram (Rapp P...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: " Efficacy of the Valsalva Maneuver on Needle Projection Pain and Hemodynamic Responses During Spinal Puncture"
... to the third minutes after that were statistically different between the study groups (P= 0.016). Post Hoc Tukey test showed there was statistical difference in HR between the ball and the ... ringer lac- tate solution. Spinal anesthesia was performed in lat- eral position by 25-guage Quincke needle without introducer. The puncture pain was assessed by the patients, immediat...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"
... thin layer chromatography. The reaction prod- uct was inspissated by the rotary evaporator and consecu- tively und covered with ether. The product 16 precipitates voluminously, depending on the ... constantly. In the process the reaction solutions colour changes to yellowish. The reaction batch was stirred continuously over night and concentrated by the rotary evaporator....
Ngày tải lên: 26/10/2012, 08:57
Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"
... of the cytoch- rome P450 (CYP) enzymatic system, is responsible for the metabolism of tacrolimus [10]. Specifically; tacro- limus is mainly metabolized by CYP3A4 and CYP3A5 enzyme isotype. CYP3A5 ... predict the amount of CYP3A5 protein accurately as it can be affected by other factors, genetic (expression of m-RNA, stability of CYP3A5 protein, dual metabolic pathway via CYP3A4 and...
Ngày tải lên: 26/10/2012, 09:32