Báo cáo y học: " Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts" ppt

... et al., Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibro- blasts Genome Biology 2010, 11:R5 Mehta et al. Genome Biology 2010, ... nuclear actin:myosin motor function. Nuclear myosin 1β is required for chromosome territory repositioning in HDFs placed in low serum In an effort...

Ngày tải lên: 09/08/2014, 20:21

... by eliminating variables that are already incorporated into the DAS28 (or are highly related to them such as CRP and 68 tender joint and 66 swol- len joint count) and taking into account only ... evaluating insufficient response to infliximab therapy (especially in daily practice) and that this variable can only slightly be improved by adding sup- plemental variables. DAS was deve...

Ngày tải lên: 09/08/2014, 06:23

... Ganglioneuroblastoma; (IRF3): Interferon regulatory factor 3; (NB): Neuroblastoma; (PKR): Double-stranded RNA-dependent protein kinase; (poly(I:C): Polyinosinic-p olycytidylic acid); (TLR): Toll-like receptor. Acknowledgements This ... TLR3 agonist, polyinosinic-polycytidylic acid (poly(I:C)), on the growth of human NB cells was evaluated by WST-1 cell proliferation assay, flow cytometry...

Ngày tải lên: 10/08/2014, 10:20

... risk factors for acquiring HCV infection were related to injection drug use and tattooing. Mild and moder- ate liver inflammation determined by Knodell score was presented in the majority of patients ... regarding the influence of on-treatment factors during therapy. The purpose of our analysis was to identify clinical, biological, vi- rological and histological predictive factors...

Ngày tải lên: 26/10/2012, 09:39

... used as a tool for (a) increasing the catalytic efficiency of enzymes in the biotechnology industry (by enhancing the coupling of dynamics to the reaction coordinate), and (b) producing more effective ... nss4@le.ac.uk Abbreviations:TST,transitionstatetheory;TTQ,tryptophantrypto- phylquinone; MADH, methylamine dehydrogenase; AADH, aroma- tic amine dehydrogenase; TMADH, trimethylamine dehy...

Ngày tải lên: 31/03/2014, 23:20

... is induced by AGE, can contribute to the inflammatory cycle by the induction of proinflammatory cytokines, via the nuclear factor-κB pathway [21]. No studies have yet examined RAGE expression in ... Nε-(car- boxymethly)lysine (50 mg/ml) inhibited the binding of poly- clonal anti-IgG-AGE antibodies to IgG-AGE by 40% but did not inhibit RF binding to IgG. Lysine at the same con-...

Ngày tải lên: 09/08/2014, 01:21

... a functional point of view, chemokines can be broadly classified into two groups: inflammatory and homeostatic [4]. The inflammatory chemokines are induced by proin- flammatory stimuli and control ... neogenesis by a lymphotoxin-dependent mechanism or recruit T cells to the inflamed tissues by a lymphotoxin-independent mechanism. Taken together, our findings suggest that CCR7 + memor...

Ngày tải lên: 09/08/2014, 06:22

... 3 Inflammatory cytokines were induced by human IL-32β in miceInflammatory cytokines were induced by human IL-32β in mice. (a) Raw 267.4 was cultured with the supernatant of human IL-32β (h IL-32β) ... generally dependent on the TNFα-inducing effect in these mouse models of inflammatory diseases. Discussion TNFα is a potent proinflammatory cytokine related to the pathogenesis...

Ngày tải lên: 09/08/2014, 08:23

... N 1 ,N 11 - diethylnorspermine (DENSPM) which induces a rapid depletion o f all polyamines by downregulating the activity of the biosynthetic e nzymes and upregulating the activity of the catabolic enzyme ... the induction of SSAT results in the acetylation of spermine and spermidine, which are subsequently oxidized by polyamine oxidase to form spermidine and putrescine, respect...

Ngày tải lên: 17/03/2014, 23:20