Báo cáo y học: "Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays" pps
Báo cáo y học: "Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays" pps
... is properly cited.MethodSubstantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arraysLuca Santuari1, Sylvain Pradervand2,3, ... al., Substantial deletion overlap among diver-gent Arabidopsis genomes revealed by intersection of short reads and tiling arrays Genome Biology 2010, 11:R4 ... detection of larger deletions is less straightforward. Here, we analyzed four divergent Arabidopsis accessions and found that intersection of absent short read coverage with weak tiling array hybridization...
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Báo cáo y học: " Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays" ppt
... diver-gent Arabidopsis genomes revealed by intersection of short reads and tiling arrays Genome Biology 2010, 11:R4Santuari et al. Genome Biology 2010, 11:R4http://genomebiology.com/2010/11/1/R4Page ... combination of UHTS with tiling array analysis is a valid and economical approach to reli-ably flag deletions in divergent genomes. Analysis of thefour divergent genomes suggests that deletions ... pre-dicted from intersection of UHTS and tiling arrays.Additional file 7Script for intersection of UHTS and tiling array dataScript for computing the UHTS coverage and signal ratio of array tiles.Additional...
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Báo cáo y học: "Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized" ppsx
... 400, and 800mg hydroxyapatite/cm) provided by the system manufacturer.The tissue mineral density was calculated only for voxelsexceeding the threshold (that is, only for voxels occupied by mineralized ... density, the X-ray attenuation of eachvoxel was converted to mineral density using a calibrationcurve that was generated from a scan of a set of five hydroxya-patite phantoms of known density ... trabecular number,thickness, and spacing, structure model index, connectivitydensity, and degree of anisotropy. We computed the mean and standard deviation for Teach parameter, and the unaffectedbone...
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Báo cáo y học: "Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation" pdf
... isolated from serum by ultracentrifugationat a density of 1.063 g/ml and were kindly provided by VincentA. Rifici and Avedis K. Khachadurian from the Department of Medicine of our medical school ... analysis of chondrocyte extractsSDS-PAGE and subsequent immunoblot analysis of chondrocyte extracts. Primary confluent articular chondrocytes in 60-mm Petri dishes were washed and finally set ... chondrocyte and explant cul-tures [9-13]. These effects include stimulation of proteoglycansynthesis, inhibition of the degradation of proteoglycans, and inhibition of matrix metalloproteinase-3 synthesis...
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Báo cáo y học: " Sarcoid reaction associated with Merkel cell carcinoma revealed by fluorodeoxyglucose positron emission tomography: a case report" ppt
... cell granulomas. The lungs, lymph nodes,liver, spleen, ski n, eyes, small bones of the hands and feet and the salivary glands are most often affected [1]. Adiagnosis of sarc oid reac tion is ma ... A copy of the writ ten consent is availabl efor review by the Editor-in-Chief of this journal.Author details1Department of Dermatology, Kagoshima University Graduate School of Medical and ... antibodies to cytokeratin 20 and thyroid transcription factor 1.J Clin Pathol 2001, 54:727-729.10. Kanekura T, Yonekura K, Yoshii N: Increased glucose uptake by keratoacanthoma detected by positron...
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Báo cáo y học: "P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis" ppsx
... http://www.journal-inflammation.com/content/5/1/22Page 6 of 8(page number not for citation purposes)contributes to the development and maintenance of neu-ropathic pain by inducing the synthesis of inflammatorycytokines and other neuroactive ... inflammation plays anactive role in pathophysiology of osteoarthritis [2]. Proin-flammatory cytokines are secreted from the inflamed syn-ovium and from activated chondrocytes. Cytokines suchas ... study of the TNF antagonist adalimumab in12 patients with erosive OA did not significantly improvethe signs and symptoms of the disease [38] but this studywas uncontrolled, small and of short...
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Báo cáo y học: "Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators"
... responsibility for theintegrity of the data and the accuracy of the data analysis. MK contributed tostudy concept and design, to analysis and interpretation of data and to draft-ing of the manuscript and ... supported by Astellas, Wyeth, Bayer, Pfizer, and Johnson and Johnson (J&J). MK and DN have not received any fees for involvement in thisstudy or manuscript. SM, AQ, and NK are employed by Johnson ... design, analysis of results, interpretation of findings, and drafting of the paper.Independent statistical analysis. The accuracy of the data analysis was inde-pendently verified by William...
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Báo cáo y học: " Serum lipid profiles among patients initiating ritonavir-boosted atazanavir versus efavirenz-based regimens" doc
... Comparisons of causes of death and mortalityrates among HIV-infected persons: analysis of the pre-, early, and late HAART (highly active antiretroviral therapy) eras.J Acquir Immune Defic Syndr 2006, ... Inves-tigators) at New York City/Bronx Consortium (Kathryn Anastos); Brook-lyn, NY (Howard Minkoff); Washington, DC Metropolitan Consortium (Mary Young); The Connie Wofsy Study Consortium of Northern Califor-nia ... study design, dataanalysis, drafting and critical review of the manuscript.AcknowledgementsThis study was reviewed and approved by the Institutional Review Boards of the participating sites and...
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Báo cáo y học: "Electronic patient record use during ward rounds: a qualitative study of interaction between medical staff"
... observation period of 13 months: 1month prior to deployment of the EPR, 4 months after deploy-ment of the EPR, and 1 year after deployment of the EPR.Each time, six separate, randomly selected patient ... months after deployment of the system, and the effects of the introduction of the EPR on group interactionwere discussed. Patient privacy was ensured at all times by avoiding capture of images that ... case loses his ability to guide thefocus of the group and, not surprisingly, the gaze of the medi-cal staff in the outer ring tends to wander.One year after deployment of the EPR, while the...
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Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"
... is mainly metabolized by CYP3A4 and CYP3A5 enzyme isotype. CYP3A5 polymorphisms seem to affect tacrolimus kinetics at a greater degree com-pared to CYP3A4 ones and thereby, these polymor-phisms ... used and bands were detected by a short wavelength UV transilluminator (Figure 1). CYP3A5*1/*1 genotype gives 148-, 125- and 20- bp bands, CYP3A5*3/*3 genotype gives 168- and 125-bp bands and ... the amount of CYP3A5 protein accurately as it can be affected by other factors, genetic (expression of m-RNA, stability of CYP3A5 protein, dual metabolic pathway via CYP3A4 and CYP3A5, linkage...
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