Báo cáo y học: "Tandem repeats modify the structure of human genes hosted in segmental duplications" docx

... manually analyzed all these 40 modifications in order to verify the effect of the repeats on the resulting pro- teins. In the majority of cases, the reading frame of the origi- nal protein is ... retention of repeats that can significantly diversify the sequence of the encoded proteins. Fifty percent of variable ITRs modify protein sequences In agreemen...

Ngày tải lên: 09/08/2014, 20:21

... might in turn result in the uncertainty of the strategy for its treatment. While further delineati n g the clinicopathological and radiological features, and summarizing the surgical therapy strategy ... experience with the management of disseminated disease is very limited in the literature 6 , therefore, attention to the therapy strategy of this neoplasm in...

Ngày tải lên: 25/10/2012, 11:40

... priori hypothesis was that the birth order effect may interact with the genetic predisposition of the off- spring in influencing future atopic manifestations. In order to test this hypothesis, ... Each of these SNPs had a minor allele frequency ≥ 19%. Using the Haploview program [26], three of the five single nucleotide polymorphisms (SNPs) of the interleu- kin 13 gene...

Ngày tải lên: 08/08/2014, 21:20

... 4). Effect of handling on BDNF immunoreactivity in the CA4 region of the hippocampusFigure 3 Effect of handling on BDNF immunoreactivity in the CA4 region of the hippocampus. Handling resulted in increased ... evidence indicates that among the serotonin recep- tors, the type 1A are involved in the etiopathogenesis of certain types of depression [23,24] and i...

Ngày tải lên: 08/08/2014, 21:20

... differentiation of emotions. Psychosomatic Medicine 1992, 54(4):422-435. 7. Hetherington MM: The physiological-psychological dichotomy in the study of food intake. Proceedings of the Nutrition Society 2002, ... effect of listen- ing to chewing sounds on the pleasure of eating. The pleasure of eating is influenced by many parameters. In addition to satiation of one&...

Ngày tải lên: 08/08/2014, 21:20

... participated in analysing the data and writing the paper. AL participated in the genetic and statistical analysis. HSA participated in designing the study, analysing the data and writing the paper. ... participated in designing the study, analysing the data and writing the paper. All authors read and approved the final manuscript. Competing interests The authors...

Ngày tải lên: 08/08/2014, 23:21

... proteinase genes are regulated by TNF-induced MEK/ERK signalling We further analysed the lists of genes that were induced by TNF using specific gene ontologies. Analysis of the list of TNF-induced, ... TNF-activated NFB-DNA binding activity. The regulation of NFB-DNA binding in primary cells can therefore be explained by the non- specific effect of DMSO on NFB...

Ngày tải lên: 09/08/2014, 01:22

... example of a system for monitoring changes in gene expression that may be applied clinically. By measuring the expression levels of 11 different genes associated with immune system pathways in peripheral ... approaches to analyzing the properties of a substance at the cellular level and to deriving a more complete picture of the impact of a treatment on the human b...

Ngày tải lên: 09/08/2014, 08:22

... review. Interventions The interventions included (a) hydrotherapy, which was prima- rily of low intensity and involved walking, leg swinging, and mobility exercises; (b) land-based swinging, mobility, and stretching ... pain included the VAS; the pain subscale of the Harris Hip Score; and/or the pain subscale of the Health Related Quality of Life Table 1 Level of evidenc...

Ngày tải lên: 09/08/2014, 14:22