Báo cáo y học: " Unraveling the genomic diversity of small eukaryotes" potx

... ARTICLE Unraveling the catalytic mechanism of lactoperoxidase and myeloperoxidase A reflection on some controversial features Elena Ghibaudi and Enzo Laurenti Dipartimento di Chimica I.F.M., Universita ` di Torino, ... exclude that the radical plays a role in the autocatalytic binding of heme to the apoprotein, a post-translational modification...

Ngày tải lên: 20/02/2014, 02:21

... Arg16 and Glu20. The biological impact of the Aib1 5 and D -Phe12 modifications on the synthetic CRH analogue is illustrated by the peptide binding affinity enhancement towards the CRH receptor and ... towards the design and synthesis of new molecules with higher binding affinity and enhanced stability against biological degradation and possibly biological ac...

Ngày tải lên: 17/03/2014, 10:20

... with 2 lg of the reporter plasmid pCAPCAT, and either 0.5 lg of each of the clones of the overlapping AcMNPV k library or 1.0 lg of each plasmid of the overlapping lef library as described by Passarelli ... focus of this paper was to further elucidate the roles of replication LEFs and the nature of the AcMNPV replication complex by studying their inte...

Ngày tải lên: 23/03/2014, 21:20

.. . antisense oligonucleotides. Eur. J. Pharm. Biopharm. 50, 101–10 9. 1 0. Gamper, H.B., Parekh, H., Rice, M.C., Bruner, M., Youkey, H. & Kmiec, E.B. (2000) The DNA strand of chimeric RNA/ DNA oligonucleotides .. . mutagenesis of the factor IX gene by chimeric RNA/ DNA oligonucleotides. Nat. Med. 4, 285–29 0. 2 8. Kren, B.T., Parashar, B., Bandy...

Ngày tải lên: 31/03/2014, 08:20

... immune-modulatory potential. Five statins are currently available within the UK: pravastatin, simvastatin, fluvastatin, atorvastatin and rosuvastatin; in addition, lovastatin is available in other countries. ... whereas fluvastatin, atorvastatin and rosuvastatin are entirely synthetic [1]. Lovastatin and simvastatin are of the lactone Review Do the pleiotropic effects of...

Ngày tải lên: 09/08/2014, 06:22

... genomic surveying of gene polymorphisms in Chlamydia trachomatis<p>By comparing two fully sequenced genomes of <it> ;Chlamydia trachomatis </it>using competitive hybridization ... not highly ranked in any of the other strains, the results indicated that the trp operon was present in the remainder of the strains. The CT868 gene region of strain L1/...

Ngày tải lên: 09/08/2014, 20:20

... p300, to primary response genes to maintain an active chromatin acetylation signature. Inducible transcription factors then recruit different acetylases that modify a different set of lysines on the ... respec- tively, were acetylated in the unstimulated cells, only 3% (two genes) of the promoters of primary response genes became transiently acetylated at 0.5 h followi...

Ngày tải lên: 09/08/2014, 20:20

... complementary to the projects in UNICORN, showing how the systematic comparative analysis of core and accessory genes of chytrids can shed light on the origin of complex eukaryotic features such as the ... parasite of members of the family Resedaceae. The sequences of metagenomes - the total DNA of microbial populations of environmental samples - allows acc...

Ngày tải lên: 09/08/2014, 20:21

... of 3 Kyle Brown, public policy fellow at the American Society for Biochemistry and Molecular Biology, has put together some initial data that illustrate this looming crisis. Using the total ... billion is exactly the sum that BP has been forced to pay by the US government as a penalty for the Gulf of Mexico oil spill. I don’t know whether to laugh at that coincidence or just...

Ngày tải lên: 09/08/2014, 20:22

... the early expression of PAX6 in humans (similar to their previous results with rhesus monkey embryonic stem cells), may have been a step in the evolution of the highly evolved forebrain of ... dataset they gener- ated to compare the gene-expression profile of human embryos with that of human embryonic stem cells (hESCs) maintained in culture. ey found that ap...

Ngày tải lên: 09/08/2014, 20:22

... purposes) Implementation Science Open Access Research article Investigating the complementary value of discrete choice experiments for the evaluation of barriers and facilitators in implementation research: a ... complemen- tary value for the evaluation of barriers and facilitators, the choice of implementation strategy will be base...

Ngày tải lên: 11/08/2014, 05:21

... Access Research article Can the collective intentions of individual professionals within healthcare teams predict the team's performance: developing methods and theory Martin P Eccles* 1 , ... measures of the behaviour of healthcare professionals. The aim of this study was to explore the relationship between the theory of planned behaviour...

Ngày tải lên: 11/08/2014, 05:21

... determine the direction of an effect. This applies to hypotheses C and D. Because (A) the number of applied changes is hypothesised to be influenced by the presence of the right conditions and (B) an ... organisa- tion, and external change agent support (for information Study model: hypothesised relations between conditions, applied changes and outcomesFigu...

Ngày tải lên: 11/08/2014, 05:21

... M, Pittet J-F: Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion. Crit Care 2009, 13 :R174. 2. Peltz ED, ... clearly demonstrating a role for HMGB1 in contributing to mortality in severe infection [6 ,11 ]. While initial studies postulated that the benefit from blocking HM...

Ngày tải lên: 13/08/2014, 19:20

... is, they have the property of self- renewal. Second, when introduced into a host blastocyst they contribute to all tissues and even the germ cells of the result- ing chimeric animal: they have the ... further functional analysis. Ivanova et al. [2] then assessed the effects of the loss of each of these proteins on the ES cells’ capacity for self-renewal. To do this they devis...

Ngày tải lên: 14/08/2014, 17:22