Báo cáo y học: "Searching for SNPs with cloud computing" ppt

... agrees substantially with the true calls, with greater than 99% precision and sensitivity overall for chromosome 22. Performance for HapMap SNPs is noticeably better than for novel SNPs, owing to ... SOAPsnp's ability to adjust SNP-calling priors according to known allele frequencies. Performance is similar for homozygous and het- erozygous SNPs overall, but novel hetero...

Ngày tải lên: 09/08/2014, 20:21

... been analyzed for purity and conformation by the same methods as the underivatized ones. N-Methylation. The derivatization was performed w ith formaldehyde in the presence of NaBH 3 CN, e ssentially ... 0.1 M acetic acid. N-Acetylation with acetic anhydride. The derivatization was performed essentially as described previously [40] at 0 °C. Because acetic anhydride quickly hydrolyzes to ac...

Ngày tải lên: 21/02/2014, 15:20

... Obesity and Asthma 57 45. Jarvis D, Chinn S, Potts J, et al. Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey. Clin ... Mary Cheang, M. Math We investigated the association between airway hyperresponsiveness (AHR) and obesity in adults referred for confirmation of asthma diagnosis. Data were analyzed for ob...

Ngày tải lên: 08/08/2014, 21:20

... with atypical antipsychotic drugs. Although understanding of the pathophysiology of akathisia remains limited, it seems that a complex interplay of several neurotransmitter systems might play ... freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit Furuse and Hashimoto Annals of General Psychiatry 2010, 9:11 http://www.annals-general-psychiatry.com/c...

Ngày tải lên: 08/08/2014, 23:21

... be performed to clarify the role of sigma-1 receptors in the efficacy of fluvoxamine for akathisia. Furuse and Hashimoto Annals of General Psychiatry 2010, 9:17 http://www.annals-general-psychiatry.com/content/9/1/17 Open ... precise mechanisms underlying antipsychotic drug-induced akathisia are cur- rently unclear. A number of neurotransmitter systems play a role in the complex pathophysio...

Ngày tải lên: 08/08/2014, 23:21

... split by trypsin treatment (0.05% trypsin, 0.02% EDTA; Biochrom) at 75% confluence. Flow cytometry analysis of cells Either isolated cells from OC were directly used for flow cytometric analysis ... lysed in 600 µl lysis buffer with 6 µl mercaptoethanol, by using the RNeasy ® system and reverse transcription was done with Omniscript™ RT Kit (all Qiagen, Hilden, Germany), in accordance...

Ngày tải lên: 09/08/2014, 01:23

... discrimination assay (Applied Biosystems). The genetic association analyses for each SNP and haplotype were performed using the Transmission Disequilibrium Test and the genotype relative risk. CI: ... the 4q27 gene region. In that study the rs6822844-T allele was reported to be a perfect proxy for a haplotype that is highly associated with autoimmune diseases with frequencies of 0.13...

Ngày tải lên: 09/08/2014, 14:20

... technique for diagnosis of nerve root avulsion compared with CT myelography with axial view. Methods: CT myelography was performed with penetration of the cervical subarachnoid space by the contrast ... contributions HY designed the study, reviewed the images, performed myelography, helped perform surgeries, and drafted the manuscript. KD conceived the study and performed sur- geries....

Ngày tải lên: 10/08/2014, 10:20

... subject, cross-sectional study. Group 1(NEW), persons with Type 2 DM diagnosed for less than 2 years (n = 80); Group 2 (EST) persons with Type 2 DM diagnosed for more than 2 years (n = 91), and Group ... 80 persons with Type 2 DM diagnosed for less than two years (NEW), and a group of 91 persons with established Type 2 DM of more than 2 years since diagno- sis (EST). Both groups...

Ngày tải lên: 10/08/2014, 21:23

... RevVaccines 2008:151-3. 14. Schoenly KA, Weiner DB: Human immunodeficiency virus type 1 vaccine development:recent advances in the cytotoxic T- Iymphocyte platform "spotty business". J Virol ... Stein Judy A, Roederer Mario, Nabel Gary J, Graham Barney S, the Vaccine Research Center 001 Study Team: Safety and Immu- nogenicity of a Gag-Pol Candidate HIV-1 DNA Vaccine Administered by...

Ngày tải lên: 11/08/2014, 08:21