Báo cáo y học: "Genome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays" docx

... following hypothesis what had happen to the influenza when it went to France. The first theory that was offered was that this “Spanish flu” was actually a different disease. Decades later phylogenic ... Introduction The death toll of the First World War failed to inflict the human casualty rate that the 1918-1919 Influenza Pandemic did. Little progress has yet b...

Ngày tải lên: 02/11/2012, 11:12

... research The abilities of improved schizophrenia patients to work and live independently in the community: a 10-year long-term outcome study from Mumbai, India Amresh Kumar Srivastava* 1,5 , Larry ... Meghana Thakar 1 , Nilesh Shah 3 and Gurusamy Chinnasamy 4 Address: 1 Mental Health Foundation of India (PRERANA Charitable Trust) and Silver Mi...

Ngày tải lên: 08/08/2014, 23:21

... from animals cannot always be extrapolated to humans. Bjelle [36] has analysed the mechanical response of human knees and found an increase in glycosaminoglycan production in load- bearing areas. ... aggrecan and type II collagen in OF and OA cartilageAnalysis of aggrecan and type II collagen in OF and OA cartilage. Ratio of aggrecan to type II collagen in the cartilage...

Ngày tải lên: 09/08/2014, 08:22

... citation purposes) Vol 9 No 5 Research article Quantitative gait analysis as a method to assess mechanical hyperalgesia modulated by disease-modifying antirheumatoid drugs in the adjuvant-induced ... Chicago, IL, USA) was used to analyze the data. Through- out the study, the mean ± standard error of means was used to describe the data in the f...

Ngày tải lên: 09/08/2014, 10:21

... Suarez A, Junker P, Laustrup H, Gonza- lez-Escribano MF, Martin J, Abderrahim H, Alarcon-Riquelme ME: Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. ... independently validated loci that, together with additional targets generated by larger GWAS, can be used to piece together the key pathways involved in lupus pathogenesis, with each...

Ngày tải lên: 09/08/2014, 14:22

... prioritizing candidate disease genes and quantifying the disease- disease associationsFigure 1 Construction of an integrated functional linkage network (FLN) with applications in prioritizing candidate disease ... experiments, and functional associations mapped from yeast, worm, and fly (organisms distant to human in the evolutionary tree). Predictions from th...

Ngày tải lên: 09/08/2014, 20:20

... 1.0 (a) (b) Log R ratio -1.0 -0.5 0.0 0.5 1.0 0.0 0.2 0.4 0.6 0.8 1.0 B Allele frequency MDA_175 MDA_468 AA AB AAB AABB ABB BB ABBB AABBB AAABB AAAB AA A AB BB B AAAB AABB ABBB BBB AAA AAB ABB ... GeneChip SNP 6.0 array. BLC_B1_T45 tumor sample measured on two SNP- array platforms, analyzed by using GAP, and superimposed by color code: (a) GAP for Affymetrix; and (b) GAP for...

Ngày tải lên: 09/08/2014, 20:20

... and u se information stored in genome databases, is an essential part of genomic and bioinformatic analysis [1-4]. While now primarily a basic research tool, analysis of genome annotation information ... Database: A tool for annotation and analysis of control regions of genes regulated by Nuclear Factor I transcription factors. Journal of...

Ngày tải lên: 10/08/2014, 09:22

... TNFα, IL-8 release could be detected in the S. pneumoniae induced JNK-dependent IL-8 and IL-6 release by human lung epithelial cellsFigure 2 S. pneumoniae induced JNK-dependent IL-8 and IL-6 release ... citation purposes) Respiratory Research Open Access Research Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8...

Ngày tải lên: 12/08/2014, 16:20

... patients was waived by the local research/ethics commit- tee as this was an observational study looking at plasma DNA, a new variable measured from blood samples that were taken as part of standard ... for early risk stratification and prediction of inhospital and overall morbidity and mortality in a range of conditions including stroke [6], myocardial infarction [11]...

Ngày tải lên: 12/08/2014, 23:23

... exercise capacity Commentary Weakness in the ICU: a call to action Robert D Stevens 1 , Nicholas Hart 2 , Bernard de Jonghe 3 and Tarek Sharshar 4 1 Departments of Anesthesiology and Critical Care ... indicate a paradigm shift to a proactive approach in managing neuromuscular complications in the ICU. In a recent issue of Critical Care, Gerovasili and colleagues [1...

Ngày tải lên: 13/08/2014, 19:20

... question, there are substantial barriers to conducting such studies. â 2010 BioMed Central Ltd Figuring out what works: a need for more and better studies on the relationship between ICU organization ... assessed the association of outcomes with intensivists’ base speciality. However, very little is known about the relationships between ICU organi...

Ngày tải lên: 13/08/2014, 20:21

... in the ligand binding pocket, similar to the placement of the cyclo- propyl group of CPX in 1RTL . The cyclopropyl group is buried in the surface cavity and faces towards the aromatic ring of F43. ... displacement of the side chain of this residue, thereby changing the shape of the cavity. Thus, the V36 mutants affect only the shape of the cyc...

Ngày tải lên: 14/08/2014, 08:20

... N-terminal pro-brain natriuretic peptide in differentiating acute heart failure from chronic obstructive pulmonary disease and asthma as cause of acute dyspnea in prehospital emergency setting. Critical ... Combination of quantitative capnometry, N-terminal pro-brain natriuretic peptide, and clinical assessment in differentiating...

Ngày tải lên: 14/08/2014, 08:21

... peptidase, trypsin-like serine and cysteine proteases (12 genes), as well as proteins with putative α 2 -macroglobulin domains (three genes), which may be involved in protease inhibition. These genes ... GO:0009613 233 31278345 111112 113 632 1122 122359 1333 Molting cycle/ pup Hemocyanin, N- terminal/C-terminal I Alpha-2- macrog lobu li n I Trypsin-like serine & cysteine protease I...

Ngày tải lên: 14/08/2014, 15:20