Báo cáo y học: " Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia" docx

... R113 Research Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia Xiaobo Xia and Andrew L Kung Address: Department of Pediatric Oncology, Dana-Farber ... minority of Myc binding exclusion and that Myc binding has a stronger dependence on H3K4 me3 [30]. It is likely that preferential binding to...

Ngày tải lên: 09/08/2014, 20:20

... used flow cytometry to determine cell cycle progres- sion by quantifying DNA. Effects of inhibition of c-Myc tran- scriptional activity and inhibition of ERK1/2 activity in the presence of 5 ng/mL ... inhibitory effect of TGF1 [29-32]. The aim of the present study was therefore to reveal the role of c-Myc in mitogenic response to TGF1 in nucleus pulposus cells. The stu...

Ngày tải lên: 09/08/2014, 01:22

... the binding to chromatin. Suppression of the binding of LBR to chromatin by phosphorylation with a kinase(s) in a mitotic phase egg cytosol The affinity of NK-bead s and chromatin was decreased by preincubation ... vivo. Stimulation of the binding of LBR to chromatin by phosphorylation by a kinase(s) in a synthetic phase egg cytosol Chromatin binding of beads bearing...

Ngày tải lên: 22/02/2014, 04:20

... variability of synovial membrane his- tology, immunohistology, and cytokine mRNA expression in patients with rheumatoid arthritis. J Rheumatol 1999, 26:777- 784. 19. Hub E, Rot A: Methods for study of ... CXCL8 binding to macrophages in a lymphocyte-rich infiltrate in rheumatoid synovium. (d) CCL3 (macrophage inflammatory protein-1α) binding to macrophages in the inflamed intimal...

Ngày tải lên: 09/08/2014, 03:24

... Project of the Japanese Ministry of Public Welfare and Labor. Author details 1 Dept. of Surgery I, Tokyo Medical University, Tokyo, Japan. 2 Diagnostic Pathology, Division, Tokyo Medical University, ... Ostmark B, Benson NA: Heterogeneity of aldehyde dehydrogenase expression in lung cancer cell lines is revealed by Aldefluor flow cytometry-based assay. Cytometry B Clin Cytom 2007, 72:...

Ngày tải lên: 10/08/2014, 09:22

... Thierry Moreau 1 and Francis Gauthier 1 1 Laboratory of Enzymology and Protein Chemistry, INSERM EMI-U 00-10, University FrancË ois Rabelais, Faculty of Medicine, Tours, France; 2 Departamento de ... donors, dialysed against 3 ´ 2L25m M Tris/HCl Correspondence to F. Gauthier, Laboratory of Enzymology and Protein Chemistry, INSERM EMI-U 00-10, University FrancË ois Rabelais, Faculty o...

Ngày tải lên: 24/03/2014, 00:21

... thylakoid membranes with n-dodecyl-a, D-maltoside. Implications for the structural organization of the photosystem II, photosystem I ATP synthase and cytochrome b 6 /f complexes. Photosynth. Res. 64, 155–166. 19. ... analysis of crystalline arrays of paired membranes was focussed on the superposition of both layers, it became clear that the interaction of the rows of PSII complexe...

Ngày tải lên: 24/03/2014, 04:21

... Fujimoto, J. & Yamamoto, T. (1999) Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory com- plex capable of binding cyclin-dependent ... Banfi, S., Quarto, M., Bulfone, A. & Tirone, F. (2000) Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the ol...

Ngày tải lên: 31/03/2014, 21:21

... Bolstad 1 1 Department of Oral Sciences-Periodontology, Faculty of Dentistry, University of Bergen, Årstadveien, N-5009 Bergen, Norway 2 Broegelmann Research Laboratory, The Gade Institute, University of Bergen, ... level of 0.05. For each assay, one reaction without Multiscribe RT enzyme was included, to ensure RNA specificity of the assays. Results Influence of NOD Idd5 and...

Ngày tải lên: 09/08/2014, 10:21