Báo cáo y học: " NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitid" pot

... eight publicly available Neisseria genome sequences and stored all these data in a publicly accessible online database. The potential of NeMeSys for narrowing the gap between sequence and function ... sequenced and assembled strain 8013's genome. DV, AL and CM contributed and managed bioinfor- matics resources. DV and VP performed manual annotation and...

Ngày tải lên: 09/08/2014, 20:20

... of a catheter in the radial artery and either a central venous catheter and/ or a pulmonary artery catheter (n = 14). The latter allowed to measure the PAOP after proper wedging, the cardiac output ... peri- cardial (regional) tamponade after primary cardiac surgery. Theaimofthecurrentstudywasthereforetoevalu- ate, retrospectively, the clinical, haemodynamic and echocar...

Ngày tải lên: 10/08/2014, 09:21

... differences in data models, data access methods and file formats. This leads to the incompat- ibility of data formats for the analysis of pathway data. To avoid this, data standards are adopted by many ... retrieval from a wide variety of path- way resources, a broad effort in the biological pathways community called BioPAX was initiated. Since many less-detailed data type...

Ngày tải lên: 09/08/2014, 20:21

... injury has anti- inflammatory effects [5]. In the current paper by Schwartz and colleagues, TWEAK was assessed as a biomarker for LN in both cross-sectional and longitudinal studies. In the former, ... array of cytokines, chemokines and cell adhesion molecules. TWEAK plays a role in tissue inflammation, repair and regeneration in many diseases, including SLE [5]....

Ngày tải lên: 09/08/2014, 14:22

... endogenous human Argonautes and their miRNA partners in RNA silencing. Proc Natl Acad Sci USA 2008, 105:7964-7969. 33. Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap ... apparent false negative rate of approxi- mately 5% and a false discovery rate of approximately 19%. To systematically compare the miRTRAP and miRDeep methods, we tested the...

Ngày tải lên: 09/08/2014, 20:21

... When a user performs an analysis using Galaxy, it automatically generates metadata for each analysis step. Galaxy’s metadata includes every piece of informa- tion necessary to track provenance and ... framework for perform- ing computational analyses, systematically repeating ana- lyses, capturing all details of performed analyses, and annotating analyses. Using Galaxy Pages, resear...

Ngày tải lên: 09/08/2014, 20:22

... a PE read, ge ne annotation sets, expression values, and so on. Software and data availability FusionSeq is available for download at [34]. Data sets used in this study are available via dbGaP ... two ‘expected’ values: one is calculated analytically and the other empirically. The first quantity is DASPER (the dif- ference between the observed and analytically calculate...

Ngày tải lên: 09/08/2014, 22:23

... tropism–HIV infects CD4+ T c ells and macrophages in the periphery, and primarily infects macrophages and microglia (and rarely, astrocytes) in the brain [3]; (ii) viral adaptation in response ... Therapy 2010, 7:43 http://www.aidsrestherapy.com/content/7/1/43 Page 6 of 12 available in the public domain, the data did not exist in a well-annotated and accessible fo...

Ngày tải lên: 10/08/2014, 05:21

... capture, or on paper that is later transcribed electronically by data-entry staff. While analytical data can also be entered manually, many parameters may be outputted electronically by labora ... and analysis. The system also communicates bi- directionally with a clinical research information system (CRIS) that manages the analytic data. 2 Construction and Content To provide a ra...

Ngày tải lên: 10/08/2014, 09:22

... The hypothesis tested was that natural starch and sucrose enzyme inhibitors (amylase and sucrase) would diminish and/ or slow the breakdown of starch and sucrose in the gastrointestinal tract, ... to inhibit amylase and/ or sucrase – bean extract, hibiscus extract, and L-arabinose, as well as a formulation containing these three ingredients to influence starch and...

Ngày tải lên: 08/08/2014, 16:23