Báo cáo y học: "Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection" ppsx
Báo cáo y học: "Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection" ppsx
... carrying deletions in genes that are crucial for the yeast growth in the given conditions will loose the competition, scored by a progressively lower intensity of their barcodes on the array over ... haploinsufficiency, in the presence of RIS and IBA, of the gene YJL167W, which encodes the yeast farnesyl pyro- phosphate synthetase Erg20p, the only known molecu...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: "Persistence with anti-tumour necrosis factor therapies in patients with psoriatic arthritis: observational study from the British Society of Rheumatology Biologics Register" pps
... another anti-TNF therapy, the date at the end of follow-up or the date the patient died, whichever came first. As patients may often stop treatment during an infection or elective surgery, any gaps in the ... assessed their efficacy and safety in PsA [2-7]. A recent meta -analysis of these trials reported substantial improvements (versus placebo) in the signs and sympto...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Oesophageal Perforation: A diagnostic and therapeutic challenge in a resource limited setting. A report of three cases." ppsx
... caused by; attempted foreign body removal either by a poorly trained endoscopist, or by one who tries to push the foreign body a head of the endoscope in to the stomach too vigorously[2] or by using ... gastrointestinal fiberoptic endoscopy has led t o an increase in the actual number of perforations [2]. The most common area of perfora- tion is in the region of the...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "Acute myopathy secondary to oral steroid therapy in a 49-year-old man: a case report" docx
... symptoms of myopathy. However, increasing the maintenance dose resulted in the appearance of symptoms of corticosteroid myopathy within 30 days in four of five patients. The group con- cluded that the ... development of myopathy in patients receiving corticosteroid therapy is not related to the age of the patient, the magnitude of the dose given or the du...
Ngày tải lên: 11/08/2014, 00:22
Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"
... history, and certain laboratory data may guide the choice of which endoscopic in - vestigation to perform first in patients with IDA, the- reby, potentially reducing the frequency of negative Int. ... respective- ly). The prevalence of gastrointestinal malignancy was 6-23% in these group patients [24, 28-29, 3] but only two men patients (2 of the 14 patients) had g...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Identification of Cellular Membrane Proteins Interacting with Hepatitis B Surface Antigen using Yeast Split-Ubiquitin System"
... Construction of cDNA Library in S. cerevisiae DSY-2 Strain The cDNA library was prepared by transforming the yeast S. cerevisiae DSY-2 strain, in which the cDNA mixture was combined with pDL2-XN ... determine the identity of the interacting proteins. 3. Results and Discussion 3.1 Principle of Split-Ubiquitin Screening System Studies have shown that the use of ye...
Ngày tải lên: 02/11/2012, 11:08
Báo cáo Y học: Identification and characterization of thioredoxin and thioredoxin reductase fromAeropyrum pernixK1 pdf
... Thioredoxin system of Aeropyrum pernix (Eur. J. Biochem. 269) 5427 Thermophilicity and thermostability of Ap TR The thermophilicity of ApTR was investigated by measur- ing the NBS 2 reductase activity ... insulin [4]. Reduction of insulin disulfide bonds can be measured by the increase in turbidity due to precipitation of the free insulin B-chain [23]. The reduction of...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo y học: "Communication between secondary and primary care following self-harm: are National Institute of Clinical Excellence (NICE) guidelines being met" ppsx
... National Institute for Clinical Excellence: Self-harm: the short-term phys- ical and psychological management and secondary prevention of self-harm in primary and secondary care. Clinical guideline ... manuscript. Acknowledgements The authors thank Ben Heyworth and Suzanne Robins for their help in designing the proforma and Dr Alan Grayson for his assistance with data collec...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers" docx
... staining. The distribution of OC cells in forward/side scatter exhib- ited no difference between isotype and antibody staining. A maximum of 2% positive cells by staining with isotype anti- body ... scatter. In these experiments, the mean frequency of every triple positive staining of cultured OC cells increased markedly compared with native OC cells (Fig. 2). The to...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies" ppsx
... study, peptides syn- thesized on pins were subjected to analysis without using the modified form of arginine. In our study, we found reac- tivity within this region only when natural arginine ... for in vitro assays [21]. Fewer than 20 proteins have been identified during the past 40 years as containing dimethylated arginines [34]. The two major catalyzing enzymes of this reac...
Ngày tải lên: 09/08/2014, 06:22