Báo cáo y học: "The Frizzled family: receptors for multiple signal transduction pathways" docx

... Biology 2004, 5:234 Genome Biology 2004, 5:234 comment reviews reports deposited research interactions information refereed research Protein family review The Frizzled family: receptors for multiple ... R: Pathway specificity by the bifunctional receptor Frizzled is determined by affinity for Wingless. Molecular Cell 2000, 6:117-126. An important paper showing that ligand affini...

Ngày tải lên: 09/08/2014, 20:20

... DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 10, 345–355. 21. Turner, J. & Crossley, M. (2001) The CtBP family: enigmatic and enzymatic transcriptional ... corepressors Jose ´ Perdomo and Merlin Crossley Department of Biochemistry, G08, University of Sydney, NSW, Australia Eos is a zinc finger transcription factor of the Ikaros family....

Ngày tải lên: 21/02/2014, 01:21

... Baron D, Pennec Y, Botton E, Mary JY, Le Goff P, Youinou P: Ability of the American College of Rheumatology 1987 criteria to predict rheumatoid arthritis in patients with early arthritis and ... BJ, Symmons DP, Barrett EM, Silman AJ: The perform- ance of the 1987 ARA classification criteria for rheumatoid arthritis in a population based cohort of patients with early inflammatory polyarthri...

Ngày tải lên: 09/08/2014, 14:22

... primary cause for the observed reduction in IQ. Conclusions In summary, with modern protocols and avoidance of XRT for very young children, the neuropsychological outcomes for XRT and chemotherapy-only ... previously treated for acute lymphocytic leukemia receiving chemotherapy as CNS prophylaxis. J Pediatr Psychol 1998, 23(5):333-340. 37. Moleski M: Neuropsychological, neuroanatomica...

Ngày tải lên: 10/08/2014, 21:23

... enteropathy into two types: an acute ischemic enteritis type and a protein-losing enteropathy type [7]. "Lupus enteritis" usually means the former, which is char- acterized by acute onset ... lupus anticoagulant, anti-beta2-glycoprotein I antibody, proteinase-3-antineu- trophil cytoplasmic antibody, myeloperoxidase-antineu- trophil cytoplasmic antibody tests were all negative. Her e...

Ngày tải lên: 11/08/2014, 12:20

... ove the cyclic sieving phenomenon, introduced by Reiner-Stanton- White, for faces of an even-dimensional cyclic polytope, under a group action that cyclically translates the vertices. For odd-dimensional ... 1. For n = d + 1, the cyclic polytope CP(d + 1, d) is combinatorially equivalent to a regular simplex, whose (k − 1)-face number is given by f k−1 (CP(d + 1, d)) =  d + 1 k  , fo...

Ngày tải lên: 08/08/2014, 12:22

... curated signaling pathway resources Pathway resource Query option for pathway molecules Genes transcriptionally regulated by pathway included? Pathways reviewed by experts? File formats available for download Textual description of ... Japan. 11 Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and Immunology, Yokohama, Kanagawa 230-0045, Japan. 12 Laboratories of D...

Ngày tải lên: 09/08/2014, 20:21

... of the IL-1 receptor accessory protein (IL-1RAcP), which is necessary for signal transduction. IL-1Ra negatively regulates IL-1 activity by competing with IL- 1 for binding to IL-1RI. Binding ... have involved dysfunction of antigen-presenting cells; B cells and autoantibody production; T cell reactivity; and, recently, cytokines (for review, see [17]). Indeed, it is widely recognize...

Ngày tải lên: 09/08/2014, 08:22

... dena- turation cycle of 94°C for 10 minutes followed by 37 cycles of denaturation at 94°C for 40 seconds, with an annealing tem- perature at 67°C for 30 seconds followed by an elongation step at 72°C for ... anomalies [7,8]. Angiogenesis also plays a key role in RA when the synovial membrane becomes hyperplasic and destroys the cartilage. We can observe an excess of blood cells (macro...

Ngày tải lên: 09/08/2014, 10:20

... rhIL-15 plus rhIL-21 for 7 days. On day 7, NK cells were subjected to the cytotoxicity assay. To test cytotoxicity, a standard 51 Cr- release assay was performed. K562 cells were incubated for 1 hour ... rhIL-21 for 5 and 7 days. On days 5 and 7, cells were stained with several conjugated antibodies (see 'Cell staining for flow cytometry', above) and six-colour analysis by...

Ngày tải lên: 09/08/2014, 10:22