Báo cáo y học: "START lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors" potx

... lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors<p>A survey of proteins containing lipid/sterol-binding StAR-related ... lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors Kathrin Schri...

Ngày tải lên: 09/08/2014, 20:20

... erosive disease, including large joint involvement, and were refractory to com- bination therapy with DMARDs and, in four patients, with tumour necrosis factor (TNF)-blocking agents. Heparinized whole ... treatment and compared with the avidity of TT antibodies following repeated immunizations. Synovial biopsies were obtained by arthroscopy before HDC plus HSCT, and analyzed by...

Ngày tải lên: 09/08/2014, 10:21

... complementarity-determin- ing region (CDR3)- typing of T cells infiltrating the joints has been used, aiming to identify clones that are specifically enriched in the inflamed synovia. Some CDR3- ... cells) are shown. (Panel a) Treg cells are 1.33% and 2.9% in the total lymphocyte population and within the CD4 + subset, respectively. (Panel b) Treg cells are efficiently rem...

Ngày tải lên: 09/08/2014, 13:22

... recording information on critical care resources, including the timing of introduction of METs. In addition, ANZICS maintains an Adult Patient Data- base (ANZICS-APD), which currently contains information ... undertaken using the information contained within the database. Assessment on timing of introduction of MET service We obtained information from a database maintained by the ANZICS ARC...

Ngày tải lên: 25/10/2012, 10:35

... Sp3. Receptor tyrosine kinases (RTKs) are cell surface receptors that contain intrinsic protein tyrosine kinase activity in their cytoplasmic regions. They are responsible for transmitting signals from ... activity in TM4 cells. Within this region, four protein-binding sites were detected by DNase I footprinting and gel shift assays. Three of them contained Sp1 cis-acting motifs, wh...

Ngày tải lên: 08/03/2014, 23:20

... abundantly in lactating mammary glands and is secreted in association with fat globules. This protein consists of two-repeated EGF-l ike domains, a mucin-like domain and two-repeated discoidin- like domains ... detected in various other tissues, including brain, lung, heart, kidney and spleen in some mammals such as mouse, human and bovine [7–9]. The mouse and bovine MF...

Ngày tải lên: 24/03/2014, 03:21

... not necessarily result in similar changes at the protein level and indicate that UCP3 density in SS and IMF mitochondria can be differently affected by metabolic changes. Keywords: fasting; intermyofibrillar ... Kuhne, Pierre Flandin, Jean-Paul Giacobino and Patrick Muzzin Department of Medical Biochemistry, Faculty of Medicine, University of Geneva, Switzerland Uncoupling protein-3 (U...

Ngày tải lên: 24/03/2014, 04:21

... leaving TNFα- induced NF-κB activation intact. ER-retained oligomers may independently activate novel signalling pathways leading to inflammation, may modify ER stress-induced responses, or may ... studied. Conversely, the effect of TNFR1 mutations outside immune cells also needs to be examined. Understanding the signalling pathways connecting protein misfolding and inflammation will be int...

Ngày tải lên: 09/08/2014, 10:20

... 'sympathetically maintained pain' [5]. Naturally occurring sympathetic neurotransmitters are cate- cholamines known as norepinephrine, epinephrine, and dopamine. All three substances act within the ... Diatchenko and colleagues [10] also demonstrated that COMT inhibition in rats results in a dramatic increase in sensitivity to pain. Low COMT activity may increase pain se...

Ngày tải lên: 09/08/2014, 10:21

... concentrations, respectively, are modulated by hormones and neuronal pathways coordinated by a subordinate neuroendocrine centre in the hypothalamus, which follows a strict 24-hour daily cycle. The closest similarity with ... diseases [16]. Insights into neurohormonal effects of melatonin in autoimmunity MLT is an important neurohormone mainly synthesized by the pineal gland with...

Ngày tải lên: 09/08/2014, 13:22