Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae pdf

... Access 2004Fayet al.Volume 5, Issue 4, Article R26 Research Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae Justin C Fay *§ , Heather ... expression is associated with phenotypic variation in Saccharomyces cerevisiaeThe relationship between genetic variation in gene express...

Ngày tải lên: 09/08/2014, 20:20

... silencing of viral genes, including the oncoprotein Tax, is associated with tumor onset. Conclusion: Our findings suggest that silencing is critical for tumor progression and identify two distinct mechanisms -genetic ... these findings suggest that besides genetic changes, epigenetic mechanisms such as DNA methylation and chromatin modifications might be involved in tumor -associ...

Ngày tải lên: 13/08/2014, 05:22

... expression expression is associated with is associated with is associated with is associated with good good good good prognosis in prognosis in prognosis in prognosis in gastric cancer gastric ... performed in triplicate. Immunohistochemical staining Immunohistochemical stainingImmunohistochemical staining Immunohistochemical staining A...

Ngày tải lên: 10/08/2014, 10:21

... α-sma Figure 1 Haematoxylin and eosin staining on healthy and arthritic synovial tissueHaematoxylin and eosin staining on healthy and arthritic synovial tissue. Haematoxylin and eosin staining was performed ... both the lining and the sublining adjacent to the lining. This same stain- ing pattern is found for collagen type IV. This observation implies that, in RA patients, cells from the...

Ngày tải lên: 09/08/2014, 08:23

... OA, and genetic variations in the ER-α gene may be involved in OA. Keywords: estrogen receptor, haplotype, knee osteoarthritis, polymorphism Introduction Osteoarthritis (OA) is a common disorder ... BtgI polymorphism (codon 594) in the ER-α gene and ER-α haplotypes of three polymorphisms (PvuII in intron 1, XbaI in intron 1, and BtgI in exon 8) with primary knee OA in...

Ngày tải lên: 09/08/2014, 01:23

... 1–4, weak staining; 5–8, moderate staining; and 9–12, strong staining. For the purpose of statistical analysis, the cohort was grouped into tumors with negli- gible or weak staining (N = 34) ... and cisplatin. Of the 221 patients, 88 were referred for treatment from a single institution following initial diagnosis of NPC. For logistic reasons, only patients from this hospital were included...

Ngày tải lên: 09/08/2014, 10:20

... vitronec- tin, fibronectin, osteopontin, sialoprotein, thrombospondin, fibrinogen, von Willebrand factor, tenascin, agrin, matrix metal- loproteinases, and prothrombin) [6]. The integrins are involved in ... reproduction in any medium, provided the original work is properly cited. Abstract The integrin αvβ3, whose αv subunit is encoded by the ITGAV gene, plays a key role in angioge...

Ngày tải lên: 09/08/2014, 10:20

... must arise during spermiogenesis since this is when the NPYq-encoded genes are expressed in nor- mal mice [3,5,28]. In keeping with the two step model for the generation of DNA damage in epididymal ... compac- tion. In addition to demonstrating the involvement of NPYq-encoded genes in regulating chromatin remodel- ing during spermiogenesis, the study also provides important insi...

Ngày tải lên: 09/08/2014, 20:22

... Bayesian sta- tistics that allows the integration of data from heterogeneous sources. Integration is important because with expression data alone it is difficult to distinguish direct from indirect ... We have also integrated information about binding motifs at promoters. Doubtless, the dominant feature in our classi- fication is gene expression. This is, however, rather spe-...

Ngày tải lên: 09/08/2014, 20:22

... nuclear staining of STAT3, and 24 cases (32.4%) with strong nuclear staining of P-STAT3. Representative staining outcomes were shown in Figure 1. There existed a consistence between the STAT3 expression and ... angiogenesis [11]. Hypermethylation silencing of SOCS (the Suppressor of Cytokine Signal- ing) genes leads to reactivation of STAT pathway, resulting in the resistance to ABT-8...

Ngày tải lên: 10/08/2014, 21:23