Báo cáo sinh học: "On the relevance of three genetic models for the description of genetic variance in small populations undergoing selection" docx
Báo cáo sinh học: "On the relevance of three genetic models for the description of genetic variance in small populations undergoing selection" docx
... the higher the decrease in genetic variance. This comparison of the Original articleOn the relevance of three genetic models for the description of genetic variance in ... intrinsically takes account of the reduction in selection intensity as compared with the theory, of the relationships betweenmates and inbreeding induced in the offspring ... the hypothesis of infinitenumber of alleles per locus. Results of FFM presented later, where the effect of the number of loci decreases when increasing the number of...
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Báo cáo sinh học: "An ’average information’ restricted maximum likelihood algorithm for estimating reduced rank genetic covariance matrices or covariance functions for animal models with equal design matrices" pot
... 0j , ie, the average information is equal to the datapart of the observed information.REML estimates of e can then be obtained by substituting the average infor-mation ... corresponding transformation of the data to new, uncorrelatedtraits. The rank of the estimated genetic covariance is determined by the number of non-zero eigenvalues of the ... that for several correlated traits, most information availableis contained in a subset of the traits or linear combinations thereof. This subsetis the smaller the higher...
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Báo cáo sinh học: "On a multivariate implementation of the Gibbs sampler" pps
... of ten using the block sampling strategy in the case of the fixed effects and breedingvalues, and a twofold reduction in the case of the variance components. In the above ... the parameters of the model. In theory, drawing from the joint posterior density takesplace only in the limit, as the number of drawings becomes infinite. The study of convergence ... the reduction of the Monte-Carlo variance using either the scalar or block sampling strategies was compared on the basis of the simpleestimator of the mean of marginal...
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Báo cáo sinh học: "On the optimality of the neighbor-joining algorithm" ppsx
... from the definition of the balanced minimum evolution tree:Lemma 3.1 The vertices of the BME polytope are the BME vectors of binarytrees. The BME vector of the star phylogeny lies in the interior of ... mean the pointed portion of the cone, i.e. modulo the lineality space.Theorem 4.1 The cones in do not form a fan. In particular, they are not the normal fan of any polytope for n ≥ 5. The theorem ... the BME cones with the NJcones. Such a comparison involves intersecting the coneswith the ( - 1)-sphere (in the first orthant) and thenstudying the volumes of their intersection by computingthe...
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Báo cáo sinh học: "Research downsizing, mergers and increased outsourcing have reduced the depth of in-house translational medicine expertise and institutional memory at many pharmaceutical and biotech co" pdf
... announcedclosure of their Sandwich Laboratories in the U.K. Thesefour sites were involved in the demise of many drugprojects due to very high rates of attrition but they werealso involved in the discovery ... Impact of the Crisis in Clinical Research on New DrugDevelopment, in Special Report: The Crisis in Clinical Research”Proceedings of a Conference Sponsored by the AFMR April 14, 2009 in Washington, ... type of knowledge but much of this type of information is not in the public domain. Here we propose the creation of a translational medicine knowledgerepository where companies can submit their...
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Báo cáo sinh học: " On the interchannel interference in digital communication systems, its impulsive nature, and its mitigation" doc
... modulating pulses), while others originate at the ‘smoothest’, most linear parts of the modulating signal. The next section clarifies the origins of this impulsivenature of the out -of- band interference.2excessively ... include the first two time derivatives of the modulatingsignal. It can be seen in the figure that (i) the onsets of the power pulses originate at the discontinuities in the second derivative of ... reduces the power of the noise outside of the channel. Also, since the time constant is small, the noiseremains impulsive (7 dBc), as can be seen in the upper panels on the left showing the in- phase/quadrature(I/Q)...
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báo cáo hóa học: " TLR3 signaling is either protective or pathogenic for the development of Theiler''''s virus-induced demyelinating disease depending on the time of viral infection" docx
... important role in controlling viral load in the CNS and in preventing the development of TMEV-induced demyelinating disease following infection with a less virulent BeAn strain in mice of the susceptible ... [16, 24]. Therefore, the relative role of TLR3-mediated signaling in the development of TMEV-induced demyelinating disease remains to be determined. In particular, the induction of strong ... GFAP staining showed markedly increased number of activated astrocytes in the white matter of the spinal cords of these mice (Fig. 3Af). Next, we examined the spinal cords of TMEV-infected...
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Báo cáo sinh học: " Research Article One-Dimensional Compressible Viscous Micropolar Fluid Model: Stabilization of the Solution for the Cauchy Problem" pot
... R×0,T for each T>0. Supposingthat the initial functions are small perturbations of the constants we derive a priori estimates for the solution independent of T, which we use in proving of the ... well.Assuming that the initial functions are small perturbations of the constants, we firstderive a priori estimates for the solution independent of T. In the second part of the work weanalyze the ... getall above estimates.4. Proof of Theorem 2.1 In the following we use the results of Section 3. The conclusions of Theorem 2.1 are immediateconsequences of the following lemmas.Lemma 4.1. It...
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Báo cáo hoa học: " Research Article Necessary and Sufficient Conditions for the Existence of Positive Solution for Singular Boundary Value Problems on Time Scales" pot
... University, Beijing 100192, China2Department of Mathematics and Physics, North China E lectric Power University, Beijing 102206, China3Department of Applied Mathematics, Beijing Institute of Technology, ... 24.Now,thisstudyis still a new area of fairly theoretical exploration in mathematics. However, it has led toseveral important applications, for example, in the study of insect population models, neuralnetworks, ... ld-continuous provided that it is continuous atall left-dense points of T and its right-sided limit exists finite at right-dense points of T.Welet CldT denote the set of ld-continuous...
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Tài liệu Báo cáo khoa học: "An Information-Theory-Based Feature Type Analysis for the Modelling of Statistical Parsing" docx
... In Proceedings of the 34th Annual Meeting of the ACL.Michael John Collins. 1997. Three generativelexicalised models for statistical parsing. In Proceedings of the 35th Annual Meeting of the ACL.J.Eisner. ... headword of the node. In the following, the units of PIQ are bits. ConclusionAmong the feature types in the same structuralposition of the parsing tree, the predictiveinformation quantity of lexical ... Analysis of Dependency-Based Feature Types for WordPrediction Models. Proceedings of EMNLP'99,University of Maryland, USA4.3 The smoothing method used in the experiment In the information-theory-based...
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