Báo cáo sinh học: "ECM approaches to heteroskedastic mixed models with constant variance ratios" docx

... of squares (¿ y 2) in each suclass. Original article ECM approaches to heteroskedastic mixed models with constant variance ratios JL Foulley Station de génétique quantitative ... easily generalized to several independent random factors if conditional maximization is performed factor by factor. The system [AI8] applies to each factor k with...

Ngày tải lên: 09/08/2014, 18:22

... cycles for heteroskedastic T e -models with < 7J estimated by EM-R.EML ((i) stage), and 15-40 cycles for fully heteroskedastic T -models or heteroskedastic T e -models with random effects. ... due to poor accuracy of within herd or herd-year variances (Brotherstone and Hill, 1986). It then suffices to use a hierarchical (linear) mixe...

Ngày tải lên: 14/08/2014, 20:20

... binding was detected with the mouse innate immunity protein DC-SIGN-R2. This synthetic protein probe also selectively bound to the nuclei of a neuron subpopulation, with no binding to the nuclei of ... common to organic synthesis but not yet amenable to protein modification. As new methodologies emerge, the study of other PTMs and that of regulatory PTMs will hope- fully provide a...

Ngày tải lên: 18/02/2014, 17:20

... long day), we want to be able both to understand what makes proteins ÔtickÕ andtoengineer proteins with native-like properties. In this review we discuss combinatorial approaches toward understanding ... genes must be pieced together with PCR-based methods. Using mixed phosphoramidites to create Ôdegen- erateÕ codons, it is not possible to specify every mix of amino acids, due...

Ngày tải lên: 19/02/2014, 12:20

... and increasing use of computational tools in the field of nicotinic receptors has led to the publication of several models of ligand–receptor interactions. These models are all based on the crystal ... on the interaction of a-conotoxins with neuronal nicotinic receptors in light of our new understanding of the receptor structure. Computational tools are expected to reveal the molecul...

Ngày tải lên: 19/02/2014, 12:20

... manually selected) 209 SYNTACTIC APPROACHES TO AUTOMATIC BOOK INDEXING Gerard Salton Department of Computer Science Cornell University Ithaca, NY 14853 ABSTRACT Automatic book indexing systems ... automatic indexing systems using sophisticated term weighting systems to assess the importance of the indexing units. [Salton 1975a, 1975b] By joining the available linguistic proc...

Ngày tải lên: 08/03/2014, 18:20

... comple- tion with LSA is to compute the total similarity of a potential answer a with the rest of the words in the sentence S, and to choose the most related option. We define the total similarity as: totsim(a, ... novels, and is identical in format to the SAT questions. Due to the source of this data, we refer to it as the Holmes data. To train models, we have experimented w...

Ngày tải lên: 16/03/2014, 19:20

... accumulation during late spermatogenesis appears to be detrimental to the germ cells and, hence, antizyme 3 apparently functions to limit any ODC expression to the early spermatogenesis. The trans- gene-derived ... forms a ternary complex with the transcription factor Smad1 and protea- somal subunit HsN3 that is translocated into nucleus in response to bone morphogenetic protein r...

Ngày tải lên: 30/03/2014, 13:20

... the theory to be put into practice, there remain two important questions to be answered :- • I-low to produce surface strings from a set of sentences to be conjoined? • tlow to produce ... enough to describe ,~ll of the l)henomenon in coordi:tation, hut also constrained enough to reject all u.'l- gr;unmatical examples without undue complications. It is difficult...

Ngày tải lên: 31/03/2014, 17:20

... appointments with MD/MOs, social workers and other treatment support staff) or scheduled to return to the CD4 nurse for periodic monitoring until deemed HAART-eligible based on clinical and/or laboratory parameters. The ... limiting non- HAART eligible patient visits to MD/MOs. To calculate this indicator, we selected all adult patients who had ini- tial visits with an MD/MO withi...

Ngày tải lên: 18/06/2014, 17:20