Báo cáo khoa hoc:" Prediction of identity by descent probabilities from marker-haplotypes" ppt
Báo cáo khoa hoc:" Prediction of identity by descent probabilities from marker-haplotypes" ppt
... of the predictions of IBD probabilities seems reasonable, withdeviations from the simulated probabilities ranging from −0.028 to 0.023(Tab. IV). Some trend can be observed namely that IBD probabilities ... veryinformative markers).2.4. Testing the prediction of IBD probabilities at locus AThe prediction of IBD probabilities given the information from markers wastested by the genedropping method [11]. ... Sciences, 2001Original article Prediction of identity by descent probabilities from marker-haplotypesTheo H.E. MEUWISSENa, ∗, Mike E. GODDARDbaResearch Institute of Animal Science and Health,Box...
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Báo cáo khoa học: Characterization of membrane-bound prolyl endopeptidase from brain ppt
... blot, 70 lg of TM, 96 lg of LM, 89 lg of MM, and 93 lgofHM; for the calnexin blot, 70 lg of TM, 96 lg of LM, 89 lg of MM, and 93 lg of HM; and for the ER-60 blot, 8 lgofMMand 5 lg of HM.Table ... activityPeptides produced by trypsin digestion of purifiedmembrane PE were analyzed by liquid chromatogra-phy–MS ⁄ MS on Qstar (HPLC ⁄ Q ⁄ TOF) or MALDI-TOF ⁄ TOF MS, which revealed that these ... attempt to clarify the identity of mPOP, weundertook the task of purifying and characterizingparticulate POP from pig brain. We have confirmedthat a significant amount of PE activity can be mea-sured...
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Báo cáo khoa học: " Prediction of clinical toxicity in localized cervical carcinoma by radio-induced apoptosis study in peripheral blood lymphocytes (PBLs)" pot
... could be explained by theTable 3: Data of apoptosis and radio-induced apoptosis (RIA) of PBLs treated with 0, 1, 2 and 8 Gy of radiation at 24, 48 and 72 hours. Cells isolated from 94 cervical ... with different levels of toxicity to a given RT schedule [3]. The treatment of cervi-cal carcinoma includes surgery and/or irradiation. The prediction of the toxicity induced by RT could help toselect ... CentralOpen AccessPage 1 of 7(page number not for citation purposes)Radiation OncologyResearch Prediction of clinical toxicity in localized cervical carcinoma by radio-induced apoptosis...
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Báo cáo khoa học: " Prediction of clinical toxicity in locally advanced head and neck cancer patients by radio-induced apoptosis in peripheral blood lymphocytes (PBLs)" ppt
... received two daily fractions of 1.2 Gyseparated by at least 6 hours to a total mean dose of 78.6 Gy (range 70.0-81.6). PBLs were isolated during fol-low-up from 10 ml of blood by density gradient centri-fugation ... patients cured from a carcinoma of thehead and neck by radiotherapy: the importance of the target volume.Int J Radiat Oncol Biol Phys 1999, 45:47-52.18. Munter MW, Karger CP, Hoffner SG, Hof H, Thilmann ... defined by two constants: a and b. a, as the origin of the curve in the Y axis deter-mining the percentage of spontaneous cell death, and b, as the slope of the curve determining the percentage of cell...
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Tài liệu Báo cáo khoa học: Degradation of tropoelastin by matrix metalloproteinases – cleavage site specificities and release of matrikines pptx
... analysis, allsamples were stored at )30 °C.MALDI-TOF⁄TOF MS analysisAnalysis of the digests was conducted by of ine nano-HPLC ⁄ MALDI-TOF ⁄ TOF MS, using a nanoHPLC sys-tem (Ultimate 3000; ... 2010 FEBS 1947(2 of 157 possible x-Ala bonds) but are cleaved to asmall extent by MMP-9 (12 of 157) and even more by MMP-12 (24 of 157).The determined cleavage site preference of MMP-7was based ... automated de novo sequencing of the nano-ESI–qTOF and MALDI-TOF ⁄ TOF MS data followed by database matching (peaks protein id and spider) [86] wasTropoelastin degradation by elastinolytic MMPs A....
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Tài liệu Báo cáo khoa học: Perturbation of membranes by the amyloid b-peptide – a molecular dynamics study pptx
... 25 ns of simulation. Pep-tide conformations are from the final frame of each simulation,which is representative of the final 50 ns of simulation time. Forperspective, the embedded region of the ... such, we attri-bute some of the disorder experienced by the nearbylipids to the motion and tilting of this embeddedsegment.Thinning of the bilayer in the presence of Ab40Because Ab40 is known ... theperturbation of lipids, which is a result of both hydro-phobic mismatch of the C-terminal region of Abwithin the lipid bilayer and the favorable interaction of the N-terminal segment of Ab with...
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Tài liệu Báo cáo khoa học: Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis doc
... expression of DR5 after PItreatment might be caused by a cumulative effect of transcriptional induction and decreased degradation of DR5 protein, thus providing an explanation for thehigh efficiency of ... activa-tion of DR5 after MG132 treatment was not affected by the knockdown (Fig. 5A). Furthermore, theknockdown of CHOP did not result in a significantattenuation of apoptosis induced by TRAIL ... triggered by PIs.RT-PCR analysis revealed a potent upregulation of c-Jun at the transcriptional level, suggesting upstreamactivation of JNKs, phosphorylation of c-Jun andenhanced c-Jun expression by...
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Báo cáo khoa học: Prediction of missing enzyme genes in a bacterial metabolic network Reconstruction of the lysine-degradation pathway ofPseudomonas aeruginosa doc
... Extraction of correlated gene clusters from multi-ple genomic data by generalized kernel canonical corre-lation analysis. Bioinformatics (in ISMB2003) 19,i323–i330.Y. Yamanishi et al. Prediction of ... were con-structed from a set of ortholog gene clusters (OGCs)obtained from comprehensive cluster analysis for all thegenes of fully sequenced organisms in KEGG GENES. Agroup of genes identified ... method was confirmed by aY. Yamanishi et al. Prediction of missing enzyme genesFEBS Journal 274 (2007) 2262–2273 ª 2007 The Authors Journal compilation ª 2007 FEBS 2263 Prediction of missing enzyme...
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Báo cáo khoa học: "Prediction of Learning Curves in Machine Translation" ppt
... provisionalbudgetting. This prediction, or more generally the prediction of the learning curve of an SMT systemas a function of available in-domain parallel data, isthe objective of this paper.We consider ... withinthe range of the set of initial points. However, it does give ameasure of the closeness of the curve fit using only the initialpoints with the gold fit using all the points; the value of this goldfit ... error of the extrapolatedcurves at the three anchor sizesThe root mean squared errors obtained by extrap-olating the learning curve are much lower than thoseobtained by prediction of translation...
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Báo cáo khoa học: Regulation of secretases by all-trans-retinoic acid pot
... 42levels is mainly achieved by modulation of secretases, namely by the induction of a-secretase activity, by inhibition of b-secretasesand ⁄ or c-secretases, or by a combination of both.This study ... of total protein was incu-bated with 1 lg of PKCa or PKCbII (both from SantaCruz) antibody in 500 lL of lysis buffer for 90 min at 4 °C.Protein complexes were precipitated by adding 40 lLofa50% ... 2009)doi:10.1111/j.1742-4658.2009.06992.xOne of the emerging approaches for the treatment of Alzheimer’s diseaseaims at reducing toxic levels of Ab-species through the modulation of secretases, namely by inducing a-secretase...
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