Báo cáo khoa hoc:" Power for mapping quantitative trait loci in crosses between outbred lines in pigs" pps

... genotype j inherited in family i ( j = 1 to 3; homozygous for either allele Original article Power for mapping quantitative trait loci in crosses between outbred lines in pigs Luis ... the gain in power in situations where disequilibrium parameter has intermediate values. Power for QTL detection in experiments involving crosse...

Ngày tải lên: 09/08/2014, 18:21

... (arrowhead) of intestine (×400). (T) ED 17.5 intestine (×100). peroxide in methanol for 15 min, and then sections were washed 4 times in PBS, for 5 min each time. Nonspecific binding was blocked ... higher in the spinal cord and spinal ganglia than in the brain during organogenesis. SOD1 immunoreactivity was ubiquitously present in developing organs and was particularly str...

Ngày tải lên: 07/08/2014, 20:23

... genotypes for ATM and BRCA1 were tested in various comparisons. Results: Haploinsufficiency of either ATM or BRCA1 resulted in an increase in the incidence of radiation-induced transformation ... Transformation Assay Radiation-induced transformation of MEF was exam ined as a surrogate for carcinogenesis in vivo. A total of 19 embryos from five litters were used and included the fo...

Ngày tải lên: 09/08/2014, 08:22

... through the DNA-binding domain. Stable binding requires simultaneous binding of all DNA-binding domains in a trimer to three adjacent nGAAn repeats. Therefore, a functional HSE contains at least ... application, e.g. screening or determin- ing binding affinities for transcription factor–DNA binding. The results of measurements of HSF1 DNA-binding activity from HeLa cells and MEFs are in...

Ngày tải lên: 18/02/2014, 14:20

... minor conformer 1 were observed, indicating that peptide linkages of Leu3–Pro4 in minor conformer 2 and Gly8–Pro9 in minor conformer 1 exhi- bit a cis configuration. Peptide SD thus exists in three isoforms ... peptides to determine the conformation and an epi- tope for mAb 4-B8(8) ⁄ E9 in order to obtain structural information showing that the peptides are bound to the antigen-bindi...

Ngày tải lên: 16/03/2014, 23:20

... 2 (pivoting) and 6 (KB). The former can be too restrictive and the latter can lead to excessive noise contamination when taking shallow syntac- tic information features into account. Instead, ... role of car- rying syntactic information and smoothing. From eqn. (3) it can be deduced that, if for a phrase s, the amount of its outgoing weights is close to the amount of its incoming weights, ....

Ngày tải lên: 17/03/2014, 22:20

... European Bioinformatics Institute’s server (http://www.ebi.ac.uk/) for clu- stalw2 [53] as Phylip-tree type and neighbour-joining clustering [26] using the alignment of complete sequences, including ... cDNA involved in cystine, dibasic, and neutral amino acid transport. J Clin Invest 91, 1959–1963. 26 Saitou N & Nei M (1987) The neighbor-joining method: a new method for reconstruct...

Ngày tải lên: 18/02/2014, 13:20

... points and stained for F-actin (red). The GFP intensity (represent- ing virus production) increased significantly over time, as seen pictorially in Fig. 3A–E and in graphical form in Fig. 3F. Infection ... target cells, includ- ing RPE cells, our study provides new starting points for understanding viral pathogenesis in the retina and advancing novel therapies to control retinal in...

Ngày tải lên: 18/02/2014, 14:20

... tetra- thiolate sites, the choice for the third incoming metal ion would be to form a bridging interaction in the a domain or to form another independent tetrathiolate site in the b domain. It is probable that ... metal-binding mech- anisms are possible in which the complete multiple metal-binding site forms in preference to partially filled binding sites. Metallothionein (MT) is a m...

Ngày tải lên: 19/02/2014, 00:20

... p38 mitogen-activated protein kinase inhibitor seems to be involved in the mechanism of salicylates in suppressing the flavivirus infection. Recently, in fact, the inhibition of virus rep- lication ... also for the correct interaction with the substrate. The binding site of the NS2B cofac- tor could be examined for a view to inhibitor develop- ment, and competitive inhibitors of the...

Ngày tải lên: 19/02/2014, 00:20