Life Long Learning in Neurology - part 8 pdf

... engaging in alerting activities prior to sleep. Idiopathic insomnia is a long- standing, often lifelong, form of insomnia without associated etiologic factors or stressors. 9. A 45-year-old ... carbamazepine metabolism by CYP3A4, resulting in increasing plasma carbamazepine levels and risk of toxicity. Other drugs producing this effect include antivirals (delavirdine, indinavir, ritona...

Ngày tải lên: 09/08/2014, 16:21

... approaches. Ann Neurol 1 983 ;14:54 3-5 53. Questions 32 and 33 refer to the following case vignette: A 2 8- year-old man has been experiencing prominent abdominal pain with waxing and waning diarrhea that ... 2-2 . 30. Aside from lipid-lowering effects, 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors (statins) have anti-inflammatory actions that reduce atheroscle...

Ngày tải lên: 09/08/2014, 16:21

... encoding which of the following proteins? A. Proteolipid protein B. Myelin basic protein C. Spastin D. Paraplegin E. Spartin Correct Answer: The correct answer is C. The history and findings ... interleukin-6 and 1 4-3 -3 proteins Correct Answer: The correct answer is E. Increased levels of interleukin-6 or 1 4-3 -3 proteins in CSF may predict the severity of long- term disab...

Ngày tải lên: 09/08/2014, 16:21

... myocardial infarction (hazard ratio = 0. 48, 95% confidence interval 0.3 6-0 .63) and stroke (hazard ratio = 0.47, 95% confidence interval = 0.2 7-0 .71), but a 7.7-fold (95% confidence interval = 3.3 - 18) ... heparin or low molecular weight heparin until warfarin becomes therapeutic. Aspirin may be started within 48 hours of stroke onset and discontinued when the INR reaches tar...

Ngày tải lên: 09/08/2014, 16:21

... pleocytosis, this occurs in the setting of polyradiculopathy in immunosuppressed patients infected with HIV type 1. 33. A 67-year-old Native American from rural Arizona with non-insulin-dependent diabetes ... regulatory element binding protein (SREBP) cleavage activating protein (SCAP) D. Increase in circulating LDL E. De-activation of sterol regulatory element binding proteins (SRE...

Ngày tải lên: 09/08/2014, 16:21

... be avoided. 35. A 57-year-old man is evaluated for a 3-month history of episodic spinning sensation triggered by turning in bed, arising from bed in the morning, or extending his neck to look ... horizontal-rotatory nystagmus. Vertical nystagmus after horizontal head shaking (cross-coupling) indicates a central lesion. 20. A 2 8- year-old man has had a feeling of mild disequilibrium...

Ngày tải lên: 09/08/2014, 16:21

... serotonin-norepinephrine reuptake inhibitor with selegiline appears to be rare, combination of these agents with selegiline should be avoided. Rasagiline, a new monoamine oxidase type B-inhibitor ... following is the most appropriate management option for this patient's inappropriate laughing and crying? A. Discontinue interferon beta-1b B. Begin desipramine C. Begin gabapentin D....

Ngày tải lên: 09/08/2014, 16:21

... Rasagiline is a relatively selective inhibitor of monoamine oxidase-B (MAO-B). Monamine oxidase-A (MAO-A) in the gut metabolizes ingested tyramine. The dose at which rasagiline loses its MAO-B ... tolcapone use. Serotonin syndrome can occur in patients taking serotonin selective reuptake inhibitors together with selegiline or other inhibitors of monoamine oxidase. 10. A 6 8- year-old...

Ngày tải lên: 09/08/2014, 16:21

... of Neurology. Neurology 2007; 68: 97 7-9 84 . 4. In attempting to define incidence of MS in a particular population, epidemiologists often have to rely on the time of disease diagnosis as the point ... region. Symptoms of vertiginous seizures include dizziness, disequilibrium, unsteadiness, spinning, or room tilting as in this patient. 35. A 9-year-old boy with partial-onset e...

Ngày tải lên: 09/08/2014, 16:21

... cobalamin and renders methylcobalamin inactive, producing clinical manifestations of cobalamin deficiency, especially in patients with preexisting subclinical cobalamin deficiency. 10. A 54-year-old ... Hart RG, Kagan-Hallet K, Joerns SE. Mechanisms of intracranial hemorrhage in infective endocarditis. Stroke 1 987 ; 18( 6):104 8- 1 056. 11. A 67-year-old man is admitted to the medi...

Ngày tải lên: 09/08/2014, 16:21