Life Long Learning in Neurology - part 5 pps

... should be avoided. 35. A 57 -year-old man is evaluated for a 3-month history of episodic spinning sensation triggered by turning in bed, arising from bed in the morning, or extending his neck to ... gradual increase in difficulty climbing stairs and arising from a chair. On physical examination, she is cushingoid in appearance. Hip flexion in 3 /5 bilaterally. Which of the fo...

Ngày tải lên: 09/08/2014, 16:21

... Rasagiline is a relatively selective inhibitor of monoamine oxidase-B (MAO-B). Monamine oxidase-A (MAO-A) in the gut metabolizes ingested tyramine. The dose at which rasagiline loses its MAO-B ... of analgesia in migraine. One mechanism may be regulation of CGRP secretions via 5- hydroxytryptamine ( 5- HT [serotonin]) 1B and 5- HT 1D receptors. CGRP appears to be elevated in the...

Ngày tải lên: 09/08/2014, 16:21

... Ann Neurol 1983;14 :54 3 -5 53 . Questions 32 and 33 refer to the following case vignette: A 28-year-old man has been experiencing prominent abdominal pain with waxing and waning diarrhea that has ... 0.9 % normal saline with insulin C. 10% calcium gluconate D. Intravenous potassium chloride (KCl) E. 3% saline 34. A 55 -year-old man with hypertension and non-insulin-dependent diabete...

Ngày tải lên: 09/08/2014, 16:21

... encoding which of the following proteins? A. Proteolipid protein B. Myelin basic protein C. Spastin D. Paraplegin E. Spartin Correct Answer: The correct answer is C. The history and findings ... interleukin-6 and 1 4-3 -3 proteins Correct Answer: The correct answer is E. Increased levels of interleukin-6 or 1 4-3 -3 proteins in CSF may predict the severity of long- term disab...

Ngày tải lên: 09/08/2014, 16:21

... Scollo-Lavizzari G, Bassetti C. Prognostic value of EEG in post-anoxic coma after cardiac arrest. Eur Neurol 1987;26:16 1-1 70. 52 A. 10 minutes B. 25 minutes C. 50 minutes D. 75 minutes ... myocardial infarction (hazard ratio = 0.48, 95% confidence interval 0.3 6-0 .63) and stroke (hazard ratio = 0.47, 95% confidence interval = 0.2 7-0 .71), but a 7.7-fold ( 95% confide...

Ngày tải lên: 09/08/2014, 16:21

... after cardiac arrest. Neurology 1997;48: 35 2-3 57 . 40. Which of the following is the primary end point in determining pentobarbital dosing for treatment of status epilepticus by induction of pharmacological ... regulatory element binding protein (SREBP) cleavage activating protein (SCAP) D. Increase in circulating LDL E. De-activation of sterol regulatory element binding prote...

Ngày tải lên: 09/08/2014, 16:21

... serotonin-norepinephrine reuptake inhibitor with selegiline appears to be rare, combination of these agents with selegiline should be avoided. Rasagiline, a new monoamine oxidase type B-inhibitor ... dopamine-blocking properties. Typical antipsychotic agents may cause a functional decline in brain-injured patients, who may already have diminished dopamine circuits from frontal lobe injur...

Ngày tải lên: 09/08/2014, 16:21

... engaging in alerting activities prior to sleep. Idiopathic insomnia is a long- standing, often lifelong, form of insomnia without associated etiologic factors or stressors. 9. A 4 5- year-old ... carbamazepine metabolism by CYP3A4, resulting in increasing plasma carbamazepine levels and risk of toxicity. Other drugs producing this effect include antivirals (delavirdine, indinavir, rito...

Ngày tải lên: 09/08/2014, 16:21

... Defining interferon beta response status in multiple sclerosis patients. Ann Neurol 2004 ;56 (4) :54 8 -5 55 . Correct Answer: Tomassini V, Paolillo A, Russo P, et al. Predictors of long- term clinical ... patient with MS has a 3% to 5% risk of developing MS over his or her lifetime. 25. A 55 -year-old man with a greater-than-20-year history of MS is seen in follow-up. He is whe...

Ngày tải lên: 09/08/2014, 16:21

... cobalamin and renders methylcobalamin inactive, producing clinical manifestations of cobalamin deficiency, especially in patients with preexisting subclinical cobalamin deficiency. 10. A 54 -year-old ... bradycardia during upright tilt B. Elevated plasma norepinephrine levels in the upright posture C. Hypotension in response to adrenoceptor agonists D. Increase in blood pressur...

Ngày tải lên: 09/08/2014, 16:21