New Concepts in Diabetes and Its Treatment - part 4 ppsx

... Regular and intermediate-acting insulin before breakfast, regular insu- lin before lunch and supper, and intermediate-acting insulin at bedtime (4 daily insulin doses). (d) Regular insulin before ... insulins) Pattern of insulin treatment (episodic therapy and CSII may increase insulin immunogenicity) Genetic factors (HLA-A2-B 44 and HLA-B 4 4- DR7 predispose to immune complicat...

Ngày tải lên: 09/08/2014, 15:20

... (lean and/ or trained sub- jects) and elevated (?15 U/ml) in insulin-resistant subjects. It should be pointed out that an apparent normal insulin level in insulin-resistant diabetic subjects indicates ... changed in type 2 patients, suggesting preserved -cell sensitivity in these patients. Insulin Secretion in Type 2 Diabetes Both impaired insulin action (insulin resistance)...

Ngày tải lên: 09/08/2014, 15:20

... MAP-K>mitogen-activated protein kinase; PC-1>an ecto-protein kinase probably interfering with insulin receptor tyrosine kinase; PI3-K>phosphatidyl- inositol-3 kinase; PIP 2 >phosphatidylinositol -4 , 5-P; PKA>protein ... threonine (the serine/threonine-spe- cific protein kinases). The receptor -subunit can be phosphorylated on serine, threonine and tyrosine residues and pos...

Ngày tải lên: 09/08/2014, 15:20

... (a) the rapid-acting, (b) the intermediate-acting and (c) the long-acting insulin. (a) The rapid-acting insulin preparations include the regular insulin as well as the semilente insulin which is ... to insulin and adjusting the pH. (c) The long-acting insulin prepara- tions include the ultralente insulin, obtained by modifying, during the prepara- tion, the pH of a mixture of zinc and i...

Ngày tải lên: 09/08/2014, 15:20

... simultaneous determinations every 4 6 h of glycemia, insulinemia and C-peptide during fasting periods of 24, 48 and 72 h. In insulinoma, glycemia falls while C-peptide and insulinemia remain near-unmodified. ... receptors metabolism in children Sepsis Intake of leucine in leucine-sensitive Insulin or insulin-releasing drugs children (sulfonylureas, pentamidine, quinine) Newborn h...

Ngày tải lên: 09/08/2014, 15:20

... diabeticretinopathyrequiringphoto- coagulation treatment and intraretinal microvascular abnormalities not requiring treatment New vessels requiring photocoagulation Intraretinal microvascular abnormalities not treatment ... caused by disturbances in the diabetic metabolism in pregnancy. Since the risk for developing diabetic retino- pathy during pregnancy increases with increasi...

Ngày tải lên: 09/08/2014, 15:20

... morbidity, and mortality in non-insulin-dependent diabetes mellitus. Lipopro- teins and coronary heart disease in non-insulin-dependent diabetes mellitus. J Diabetes Complica- tions 1997;11:137– 141 . Lopes-Virella ... lipoproteins in non-insulin-dependent diabetes mellitus. Diabet Med 1997; 14( suppl 3):67– 74. De Man FH, Cabezas MC, Van Barlingen HH, Erkelens DW, de Brui...

Ngày tải lên: 09/08/2014, 15:20

... these studies. The Scandinavian Simvastatin Survival Study (4S) included 4, 444 patients with a recent myocardial infarction or angina pectoris and an increased fasting serum-cholesterol level in the range ... overview. Diabetes 1997 ;46 (suppl 2): 58–61. Dr J. Shaw, Department of Medicine (M7), Manchester Royal In rmary, Manchester M13 9WL (UK) Tel. +44 161 276 44 52, Fax +44 161 2...

Ngày tải lên: 09/08/2014, 15:20

... transducing part, impeller displacement transducing part and signal processing part. In the fluid force transducing part, the strain generated during operation in a copper alloy coupling having ... consumption and solid suspension performance of large - scale impellers in gas - liquid - solid three - phase stirred tank reactors. Chemical Engineering Journal,...

Ngày tải lên: 20/06/2014, 06:20