International Textbook of Obesity - part 5 pptx
International Textbook of Obesity - part 5 pptx
... dehydrogenase A-Ring Reductases 5 - and 5 -reductases catalyse the reduction of the 4 ,5 double bond in the A-ring (Figure 18.2) to gener- ate 5 -or5-dihydrocortisol. These dihydro-meta- bolites are ... excess (134,1 35) . More- over, analysis of urinary metabolites of cortisol re- veals an elevated ratio of the metabolites of cortisol versus those of cortisone, and the ha...
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International Textbook of Obesity - part 3 pptx
... the antiobesity action of the obese gene product. Nature 19 95; 377 :53 0 53 2. 21. Cusin I, Rohner-Jeanrenaud F, Stricker-Krongrad A, Jean- renaud B. The weight-reducing effect of an intracereb- roventricular ... (54 ,55 ). Typically, 104 INTERNATIONAL TEXTBOOK OF OBESITY showed significant improvements in quality of life scores which may increase the likelihood of greater com...
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International Textbook of Obesity - part 1 pdf
... 25 29 30–34 35 39 40–44 45 49 50 54 55 59 Age (years) MEN WOMEN % 0 10 20 Figure 1.3 Obesity prevalence across the lifespan in the Neth- erlands. There is a consistent rise in the prevalence of ... adulthood has the form of a J-shape. The nadir of this curve usually is in the age range of 5 to 7 years of age. It has been 27THE EPIDEMIOLOGY OF OBESITY Table 1.6 Prevalence...
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International Textbook of Obesity - part 2 pdf
... a high-risk strategy really seems worthwhile. 78 INTERNATIONAL TEXTBOOK OF OBESITY In the light of these facts, three potentially inter- esting areas of screening for obesity will be high- lighted, ... ranges for Asians? % fat BMI 20—39 years 40 59 years 60—79 years Females Normal P18 .5: 25 P 25: 35 P 25: 35 P 25: 36 Obese P30 P40 P41 P41 Males Normal P18 .5: 25 P13:23 P13:...
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International Textbook of Obesity - part 4 ppt
... molecules and even some kinds of small cells (29). Although the 170 INTERNATIONAL TEXTBOOK OF OBESITY 14 Causes of Obesity and Consequences of Obesity Prevention in Non-human Primates and Other Animal Models Barbara ... (104). Glucose-lowering and Insulin-sensitizing Agents GLP-1 and exendin-4. GLP-1 (glucagon-like polypeptide-1) has been studied in non-human pri- mates (101...
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International Textbook of Obesity - part 6 pdf
... acid, on hepatic 3alpha- and 3 - hydroxysteroid dehydrogenases and 5alpha- and 5 -reduc- tase pathways of metabolism of aldosterone in male rats. Steroids 1990; 55 :52 58 . 153 . Mala S, Mahendroo ... K-W, Luo H, Albrecht ED. Cloning of the 11beta-hydroxysteroid dehydrogenase (11beta-HSD )-2 gene in the baboon: Effects of estradiol on promoter activity of 11beta-HSD-1 and -...
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International Textbook of Obesity - part 7 docx
... control- led trial ofsustained-release bupropion,a nicotine patch, or both for smoking cessation. N Engl J Med 1999; 340(9): 6 85 691. 336 INTERNATIONAL TEXTBOOK OF OBESITY The relationship of each of ... optimize 328 INTERNATIONAL TEXTBOOK OF OBESITY Figure 23.1 Summary of path analyses. DEX, blunted dexa- methasone (0 .5 mg ;1) suppression of cortisol secretion (nmo...
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International Textbook of Obesity - part 8 doc
... incidence of diabetes mel- litus. 13 .5 years of follow-up of the participants in the study of men born in 1913. Diabetes 19 85; 35: 1 055 —1 058 . 22. Haffner SM, Stern MP, Mitchell BD, Hazuda HP, Patter- son ... Physical activity and risk of prostate and testicular cancer; a cohort study of 53 000 Norwegian men. Cancer Causes Control 1994; 5: 54 9 55 6. 382 INTERNATIONAL T...
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International Textbook of Obesity - part 9 ppt
... discontinuation (55 ). A report of a 24-week dose-ranging study, recent- 456 INTERNATIONAL TEXTBOOK OF OBESITY LONG-TERM RESULTS OF DIETING Weight loss after dieting generally is 6—12 kg, most of which ... reduc- tion of the -adrenoceptor subset (56 ). Data re- garding the effects of sibutramine on food behav- iour via a variety of - and -adrenergic receptors seems...
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International Textbook of Obesity - part 10 doc
... observed, name- ly, subjects with more favourable long-term weight 50 2 INTERNATIONAL TEXTBOOK OF OBESITY Table 35. 1 BMI and risk factors in 50 -year-old men and women from SOS and in 50 -year-old randomly ... (SRM) QL SE MACL HAD-D HAD-A GHRI-CH SIP-SI SIP-RP SIP-HM SIP-A OP TFEQ-HU TFEQ-DI TFEQ-RE Surgical cas e s, we ig ht los s > 25% Surgical cas e s, we ig ht los s < 2...
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