International Textbook of Obesity - part 4 ppt

... rats (1 04) . Glucose-lowering and Insulin-sensitizing Agents GLP-1 and exendin -4 . GLP-1 (glucagon-like polypeptide-1) has been studied in non-human pri- mates (101), but its short half-life has ... Ltd. International Textbook of Obesity. Edited by Per Bjorntorp. Copyright © 2001 John Wiley & Sons Ltd Print ISBNs: 0 -4 7 1-9 88707 (Hardback); 0 -4 7 0-8 46 739 (Electronic)...

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... JD, Takemori AE et al. 4- Dimethyl- 4- ( 3-hydroxy- phenyl)piperidines: opioid antagonists with potent anorec- tant activity. J Med Chem 1993; 36: 2 842 —2850. 68. Shaw WN. Long-term treatment of obese Zucker ... quotient (RQ) is the volume of car- bon dioxide formed divided by the volume of oxy- 146 INTERNATIONAL TEXTBOOK OF OBESITY the central administration of opioid ago...

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... dehydrogenase A-Ring Reductases 5 - and 5-reductases catalyse the reduction of the 4, 5 double bond in the A-ring (Figure 18.2) to gener- ate 5-or5-dihydrocortisol. These dihydro-meta- bolites are ... excess (1 34, 135). More- over, analysis of urinary metabolites of cortisol re- veals an elevated ratio of the metabolites of cortisol versus those of cortisone, and the half-...

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... (55). A report of a 2 4- week dose-ranging study, recent- 45 6 INTERNATIONAL TEXTBOOK OF OBESITY LONG-TERM RESULTS OF DIETING Weight loss after dieting generally is 6—12 kg, most of which occurs ... development of DPP-IV resistant ana- logues of GLP-1 (123), DPP-IV inhibitors (1 24) and GLP-1 receptor agonists such as exendin -4 (125). The Leptin System Since the discovery...

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... specializing in obesity care. Chapter 075. Evaluation and Management of Obesity (Part 4) Lifestyle Management Obesity care involves attention to three essential elements of lifestyle: ... released by the Institute of Medicine recommends 45 –65% of calories from Another dietary approach to consider is the concept of energy density, which refers to the number of...

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... ISBNs: 0 -4 7 1-9 88707 (Hardback); 0 -4 7 0-8 46 739 (Electronic) Table 1.9 Prevalence of overweight? in 6- to 8-year-old children USA China Russia South Africa Brazil (1988—1991) (1993) (19 94 1995) (19 94) ... 28 Slum (poor) 1 4 Source: Gopalan ( 14) . 20– 24 25–29 30– 34 35–39 40 44 45 49 50– 54 55–59 Age (years) MEN WOMEN % 0 10 20 Figure 1.3 Obesity prevalence acros...

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... Sons, Ltd. International Textbook of Obesity. Edited by Per Bjorntorp. Copyright © 2001 John Wiley & Sons Ltd Print ISBNs: 0 -4 7 1-9 88707 (Hardback); 0 -4 7 0-8 46 739 (Electronic) Figure 4. 4 Measuring ... a high-risk strategy really seems worthwhile. 78 INTERNATIONAL TEXTBOOK OF OBESITY In the light of these facts, three potentially inter- esting areas of sc...

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... 0 -4 7 1-9 88707 (Hardback); 0 -4 7 0-8 46 739 (Electronic) likely that the poorest members of society will be at greatest risk of maternal obesity. PREVENTION AND TREATMENT OF MATERNAL OBESITY It is often ... 1999; 84: 3 745 —3 749 . 138. Edwards CRW, Benediktsson R, Lindsay RS, Seckl JR. Dysfunction of placental glucocorticoid barrier: link be- 2 64 INTERNATIONAL TEX...

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... © 2001 John Wiley & Sons Ltd Print ISBNs: 0 -4 7 1-9 88707 (Hardback); 0 -4 7 0-8 46 739 (Electronic) Table 23.2 Stages of the hypothalamic-pituitary-adrenal axis status and feedback regulation with ... control- led trial ofsustained-release bupropion,a nicotine patch, or both for smoking cessation. N Engl J Med 1999; 340 (9): 685—691. 336 INTERNATIONAL TEXTBOOK OF OBESITY...

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... 1995; 122: 48 1 48 6. 47 . Harris MI. Impaired glucose tolerance in the US popula- tion. Diabetes Care 1989; 12: 46 4 47 4. 48 . DiPietro L, Mossberg H-O, Stunkard A. A 40 -year history of overweight ... Ltd. International Textbook of Obesity. Edited by Per Bjorntorp. Copyright © 2001 John Wiley & Sons Ltd Print ISBNs: 0 -4 7 1-9 88707 (Hardback); 0 -4 7 0-8 46 739 (E...

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