Báo cáo y học: "Sinus aspergilloma in rheumatoid arthritis before or during tumor necrosis factor-alpha antagonist therapy" ppsx

... found in 3.7% of patients under- going surgery for chronic inflammatory sinusitis [12]. Sinus aspergilloma is often asymptomatic and may therefore be overlooked during the workup performed before ... carried out in the PubMed data- base, using the following keywords: (rheumatoid arthritis OR ankylosing spondylitis OR spondylarthritis) AND (aspergilloma OR fungus ball OR...

Ngày tải lên: 09/08/2014, 14:22

... Concomitant Therapy Study Group: Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti -tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy Study Group. N ... Tak PP: Tumor necrosis fac- tor alpha blockade reduces the synovial cell infiltrate early after initiation of treatment, but apparently not by induction of apoptosis in...

Ngày tải lên: 09/08/2014, 01:23

... highly dif- ferentiated state [11–16]. These inflammatory chemokine receptors are prominently expressed on effector T lymphocytes (Th1 cells) that mediate a type 1 inflammation such as RA. Interestingly, ... underneath the synovial lining layer and organize into lymphocyte aggregates with germinal centres (GCs) [19–21]. These ectopic lymphoid struc- tures share many features with secondary ly...

Ngày tải lên: 09/08/2014, 03:24

... DRB1 In the initial, retrospective study, the frequency of B cells was determined as a percentage of CD19 + lymphocytes from total T lymphocytes and B lymphocytes combined (CD3 + + CD19 + lymphocytes). ... subsequent binding to Fc receptors in rodent erosive polyarthritis models resembling RA [13]. RF production in RA is thought to occur in the synovial infiltrate in affected joints...

Ngày tải lên: 09/08/2014, 03:24

... RA-induced and RA therapy-induced hyperhomocysteinemia to CHF risk in RA has yet to be completely elucidated. Inflammatory cytokines In patients with overt CHF, levels of inflammatory cytokines (TNF-α, ... is tempting to speculate that chronic production of cytokines, including TNF-α, may affect the myocardium in RA in either an endocrine (originating in the synovium) or paracrine...

Ngày tải lên: 09/08/2014, 07:20

... 3 Probability plot: change/year in total radiographic scoreProbability plot: change/year in total radiographic score. Figure 4 Probability plot: change/year in erosion scoreProbability plot: change/year ... Linden S: Reading radiographs in chronological order, in pairs or as single films has important implications for the discriminative power of rheumatoid arthritis clinical t...

Ngày tải lên: 09/08/2014, 08:22

... regions. Methyl CpG-binding proteins use transcriptional corepressors for transcriptional silencing or may modify the surrounding chromatin of methylated regions [27]. In oncogenesis, hypermethylation ... modifications regulating inflammatory processes The transcription factor NF-κB plays a central role in the induction of genes involved in immunity and inflammation, including cytokin...

Ngày tải lên: 09/08/2014, 13:21

... plasma cells, in the inflamed synovium; and experimental studies showing, for instance, the effects of immune complexes containing rheumatoid factor on tumor necrosis factor production by macrophages. ... B cell populations in RA patients that usually lasts for 6 to 9 months. Repopulation occurs mainly by naïve B cells, whereas memory B cells can stay depleted for more than 2 years...

Ngày tải lên: 09/08/2014, 14:22

... limitation may be rectified using Magnetic Resonance Imaging to delineate the soft tissue structures. Finally, for pragmatic analysis we categorised the forefoot nominally into either medial or lateral ... foot-shoe interface pressures is increasingly used in clinical practice to determine clinical interventions, such as foot orthoses, for patients with RA, yet there is very little e...

Ngày tải lên: 10/08/2014, 21:24

... USA: Theodore Pincus, Vanderbilt University, Nashville, TN; Yusuf Yazici, NYU Hospital for Joint Diseases, New York, NY; Martin Bergman, Taylor Hospital, Ridley Park, PA; Christopher Swearingen, ... Theodore Pincus, New York University Hospital for Joint Diseases, New York, NY, USA. Acknowledgements Abbott Laboratories (Abbott Park, IL, USA) provided financial support for this study. The ......

Ngày tải lên: 09/08/2014, 01:22