Báo cáo y học: "Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4" pot
Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... from anion-exchange (AE) HPLC of water-soluble matrix (WSM) and EDTA-soluble matrix (EDTA-SM). Cysteine, hydroxylysine, hydroxy- proline, phosphoserine, proline and tryptophan were not determined. Amino acid AE-WSM ... Hydroxyproline, hydroxy- lysine and phosphoserine were not detected in WSM, WIM, EDTA-SM and EDTA-IM. The comparison of the amino acid composition of the main p...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo y học: "Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection" docx
... increasing the running speed and time as follows: day 1, 10 minutes at 10 m/min; day 2, 15 minutes at 12 m/min; day 3, 20 minutes at 15 m/min; day 4, 30 minutes at 18 m/min; and day 5, 35 minutes ... cause of joint pain and loss of mobility in older people. Osteoarthritis is influenced by genetic and environmental factors, including mechanical stress. To overcome difficulties i...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo y học: "Capturing real-life patient care in psoriatic arthritis and its risks: the challenge of analysing registry data" docx
... adjudication of the reason for withdrawal. In summary, the study by Saad and colleagues gives us important insights into daily-life use of TNF inhibitors in PsA, a disease that too often is secondary to ... reason of ineffectiveness and terminated for the reason of toxicity. This was done by censoring patients with treatment terminations other than the reason of interest in...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer" pps
... chondrogenesis of primary MSCs and to investigate whether levels and extent of hyper- trophy in vitro is influenced by the choice of transgene. Materials and methods Construction and preparation of recombinant ... analyzed histologically, immunohistochemically, biochemically and by RT-PCR for chondrogenesis and hypertrophy. Results Levels of BMP-2 and BMP-4 in the...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity" potx
... salivary glands, gastric mucosa, and lactating mammary glands [1]. NIS mediates the active transport of iodide into the folli- cular thyroid cells and, in turn, concentrates iodide in the thyroid ... pre- viously [13]. Briefly, uracil -containing single-stranded DNA (ssDNA) was prepared by transforming pBKS-NIS- 5’ into E. coli CJ236 strain. Uracil-containing ss DNA was annealed with...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "IGF-1 regulates cAMP levels in astrocytes through a β2-adrenergic receptor-dependant mechanism" pot
... results in intrinsic tyrosine kinase receptor activity and the transduction of intracellular signaling pathways, including MAPK and PI3K pathways [2]. It is becoming evident that signaling pathways ... activation of adenylyl cyclase [5,6]. Multiple sclerosis (MS) is an inflammatory de- myelinating disease of the CNS characterized by infil- tration of macrophages and T-cells...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo y học: "Assessing post-traumatic stress disorder in South African adolescents: using the child and adolescent trauma survey (CATS) as a screening tool" docx
... difficulty concentrating, avoidance of physical reminders of the event, and nightmares), suggesting that these symptoms may be more sensitive indicators of PTSD. General Implications of Findings The ... Academy of Child and Adolescent Psychiatry: Practice parameters for the psychiatric assessment of children and adolescents. Journal of the American Academy of Child and...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis" ppsx
... has not been systemat- ically examined. In the present study, we first examined paired samples of synoviocytes isolated from the erosive front of synovium and from regions not directly adherent ... of cDNA subclones with mutations was higher in the FLS than in matched synovium. This is most probably because the cells bearing mutations in the intact tissue (synoviocytes in th...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Circulating tumour necrosis factor-α bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical respone" pot
... been observed when trying to explain loss of infliximab response by the induction of anti-mouse antibodies [11]. Once again, only the demonstration of inhibitory activity in vivo would allow such ... bioactivity and its possible link to response. The bioassay is based on the induction of IL-6 and osteoprotegerin (OPG) production by synoviocytes in response to TNF-α. RA synovio...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Interleukin-18: a therapeutic target in rheumatoid arthritis" potx
... concept’ of interacting activities contributing in synergy across distinct tissue events. In particular, cytokine mediated pathology may be distinct in cartilage and bone as opposed to synovial tissue ... complex milieu of regulatory pathways described for IL-18. High affinity binding by IL-18 binding protein a and c isoforms renders these obvious neutralising agents, and earl...
Ngày tải lên: 09/08/2014, 06:22