Báo cáo y học: "Biomarkers as tools for improved diagnostic and therapeutic monitoring in systemic lupus erythematosis" potx

... with lupus disease activity indices or other clinical features was determined. High IFN scores were positively associated with increased disease activity as indicated by the SLEDAI and the Systemic ... resident mono- cytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus. Arthritis Rheum 2008, 58:1136-1145. 28....

Ngày tải lên: 09/08/2014, 14:22

... activation during blood clotting in patients and control individuals, and examined whether TGF-β 1 activation was associated with clinical phenotype, in particular inflammatory disease activity, cumulative ... full clinical assessment, including meas- urement of disease activity using the SLE Disease Activity Index (SLEDAI) [12]. Therapy was recorded, including current dose of stero...

Ngày tải lên: 09/08/2014, 08:22

... were prepared as described above. Cells were washed and incubated in PBS containing 4% heat-inactivated rat serum, and stained with anti-CD134- biotin/streptavidin-allophycocyanin and anti-CD4-FITC. ... Netherlands). Liposomes used for investigating in vitro binding and internalization contained 0.1 mol% Texas red-phosphatidylethanolamine (Molecular Probes Europe). Liposomes u...

Ngày tải lên: 09/08/2014, 06:22

... are inevitably exposed to dry month and hunger. In Japan, pre- operative fluid and electrolyte management is usually performed by intravenous therapy, and the fasting time prior to surgery seems ... fluid and electrolyte management is usually performed by intravenous therapy. We investigated the safety and effectiveness of oral rehydration therapy (ORT) for preoperative flu...

Ngày tải lên: 25/10/2012, 10:51

... multiple independent validations). The existence of Berkson’s bias has been statistically assessed [23]. Acknowledgements The Research in this study was financed partly by the Ministry of Education ... normality of CA 19.9 in patients with chronic cardiac insufficiency was dem- onstrated. In other publications, CA 19.9 has not shown as much diagnostic capacity for SCRC when...

Ngày tải lên: 03/11/2012, 11:34

... rumi- nation task which involves focusing on current feelings and personal characteristics, such as 'your feelings right now and why you are feeling this way'. The generally con- sistent finding ... illumination. Light therapy was originally used to treat seasonal affective disorder (SAD), by advancing the phase delay in circadian rhythms caused by exposure to less sunlight...

Ngày tải lên: 08/08/2014, 23:21

... in using them. In our analysis, after calling putative binding sites and removing binding sites likely to be due to non-specific mapping, 4,035 binding sites were called from the IHH015M dataset ... modules: Linker filtering, PET mapping, PET classification, Binding site calling, Chromatin interaction calling, and ChIA-PET visualization (Figure 2). First, in the Linker filtering mod...

Ngày tải lên: 09/08/2014, 20:21

... X-ray analysis and measurement of BMD. As reported previously, the femoral BMD was markedly reduced in ArKO mice and the loss of mineralized cancellous bone was evident in the distal metaphysis ... (D) were fixed and stained with hematoxylin & eosin for histological analysis. Decreases in the thickness of the endometrial and myometrial cell layers in ArKO mice were prev...

Ngày tải lên: 24/03/2014, 03:21

... other. Interestingly, by focusing on MMP-3, there may be indirect suppression of the ability of MMP-1 to destroy the extracellular matrix in RA. Competing interests The authors declare that they have ... combinations of factors for this differential regulation, emphasizing the complex interactions of the potpourri of factors present in RA tissues and their ability to differentially in...

Ngày tải lên: 09/08/2014, 14:22

... annotated in pathways by defining a FI as an interaction in which two proteins are involved in the same reaction as input, catalyst, activator and/ or inhibitor, or as components in a complex. To train the ... not necessarily indicate a biologically functional relationship; for example, two proteins may physically interact in a yeast two-hybrid experiment without this signi...

Ngày tải lên: 09/08/2014, 20:22