Báo cáo y học: "Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer" pps
... clearly separated by the proximity of the cells to the joint space and the bone respectively, alignment of the chondrocytes along the arcades of Benninghoff [29] and by the appearance of hypertrophic cells. ... differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene...
Ngày tải lên: 09/08/2014, 14:22
... 2170 25,26 clearly had an effect, decreasing cell proliferation (as measured by [ 3 H]- thymidine incorporation) by 35% and the produc- tion of IgM and IgG by the isolated tonsillar cells by 45 to 75%. This ... lymphocytes from apoptosis. 32,33 A novel factor secreted by FDCs, 8D6, is not involved in rescue from apop- tosis and is not solely responsible for maint...
Ngày tải lên: 08/08/2014, 20:23
... stimulus. Discussion In this study, we have demonstrated expression of CD47/IAP by human articular chondrocytes with predominant expression of the type 2 isoform. The type 2 isoform of CD47/IAP, ... stimulated and unstimulated cells. Tyrosine phosphorylation of a 125-kDa protein is increased after 1 minute of mechanical stimulation but this response is diminished...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo y học: "Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells" pdf
... the osteogenic differentiation of human mesenchymal stem cells (MSCs); and blockade of the activity of the BMP inhibitor increases the rate of osteogenic differentiation of human MSCs in vitro. Methods Human ... modulated extracellularly by several binding proteins, including noggin, gremlin, follistatin and chordin. The latter is a BMP antagoni...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts" pps
... the experimental work and the analysis of the data and participated in the writing of the manuscript. VD per- formed several experiments. MH participated in the analysis of the study and in the ... role in controlling cell numbers by eliminating old cells, unnecessary cells, and unhealthy cells. Deregulation of apoptosis thus can lead to the sur...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"
... acquisi- tion of data. AZ participated in the coordination of the study. AAZ participated in the design of the study, and performed the statistical analysis. RA conceived of the study, participated in the ... count and C-reactive protein level for discrimination of systemic inflammatory response syndrome and infectionEosinophil cell count and C-reactive p...
Ngày tải lên: 25/10/2012, 10:35
Báo cáo y học: "Placenta Percreta-Induced Uterine Rupture Diagnosed By Laparoscopy in the First Trimester"
... evaluated for the differential diagnosis such as appendicitis and hemoperitoneum. The gradual increase in the size of the uterus with advancing pregnancy can cause a delay in the diagnosis and appropriate ... lower uterine segment; however, in cases of uterine rupture during the first trimester, the site commonly affected is the fundus, as noted in our...
Ngày tải lên: 25/10/2012, 10:56
Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"
... one-week training period wherein they were intro- duced to the apparatus and handled by the operator daily. Testing was conducted during the last 4 hours of the day portion of the light cycle in an ... supports the hypothesis that a mechanism thorough which abnormal metabolism may ultimately influence ALS pathogenesis is through mechanisms involving reduced expr...
Ngày tải lên: 03/11/2012, 10:52
Báo cáo khoa học: Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages pdf
... observed, even in the presence of PPARc ligand, confirming the role of the enzymatic activity of visfatin and the possibility that PPARc can modulate Visfatin induction by PPARc in human macrophages ... still controversial, visfatin is thought to have insulin mimetic effects and, similarly to insulin, visfatin enhances glucose uptake by myocytes and adipocytes a...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
... pools of putres- cine, spermidine and spermine by down-regulating the activity of the polyamine biosynthetic enzymes a nd up-regu- lating the activity of the catabolic enzyme spermidine/ spermine ... in the sonicate was deter- mined by measuring the synthesis of [ 14 C]acetylspermidine after incubation with [ 14 C]acetyl coenzyme A and spermi- dine [20]. Flow cyt...
Ngày tải lên: 17/03/2014, 23:20