Báo cáo y học: "Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1β-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice" ppt

... inhibitory peptide on interleukin-1β-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice Maung-Maung Thwin 1 , Eleni ... AA, Gopalakrishnakone P: Secretory phospholipase A2 activity in the normal and kainate injected rat brain, and inhibition by a peptide derived from py...

Ngày tải lên: 09/08/2014, 14:22

... partheno- lide's inhibitory effect on inflammatory mediators includ- ing activity and expression of cyclooxygenase (COX) [4,5], generation of prostaglandins [6,7], and leukotrienes (LT) [4] and expression of ... Inhibition of the expression of inducible cyclooxygenase and proinflam- matory cytokines by sesquiterpene lactones in macrophages correlates with the...

Ngày tải lên: 11/08/2014, 08:21

... dairy, including recording their weekly training units in running, showing duration (minutes) and distance (kilometres), from inscription to the study until the start of the race. In addition, ... recovery [40]. In runners, especially, the combined ingestion of carbohydrate and protein after each training session over 6 days reduced the post exercise increase in serum creatine...

Ngày tải lên: 11/08/2014, 23:21

... prednisolone, azothioprine and cyclosporin. Seven of the patients were on antihypertensive medica- tion, consisting of a beta-blocker in five cases and nitrates in two. None of them had a history of ... by anaesthetic agents and by the continuous infusion of dopamine given during the transplant surgery [30]. Thirdly, ischaemic reperfusion injury may have affected the res...

Ngày tải lên: 12/08/2014, 18:20

... possibly because none of these samples induced any significant increase in neutrophil influx compared to the control. In addition to inducing inflammation, as indicated by cel- lular changes with in ... most pro- inflammatory metal in their study followed by manganese and nickel, while vanadium, iron and zinc induced simi- lar levels of inflammation. This study analysed the me...

Ngày tải lên: 12/08/2014, 18:21

... function. LysoPC inhibition of group IA sPLA2 activityFigure 3 LysoPC inhibition of group IA sPLA2 activity. (A.) Relationship between substrate concentration and velocity in reac- tions of group ... albumin binding does not effect the binding to PC con- taining particles and subsequently the ability of the lys- oPC to inhibit enzyme activity, or that 2), in some situation...

Ngày tải lên: 11/08/2014, 08:22

... reducing LV dyssynchrony and thereby liber- ating a further segment of the RR interval for diastole (24). Considering that direct evaluation of LV dyssynchrony is still complex and time-consuming, ... test, interventricular dyssynchrony Introduction The introduction of cardiac resynchronization therapy has recently renewed the clinical interest in the analysis of specific...

Ngày tải lên: 05/11/2012, 11:32

... enzymatic reaction steps of aldosterone synthesis from DOC, s uggesting only minor functional relevance of lysine 152 in human C YP11B2. In contrast to the insertion of glutamic acid in position 147, ... CYP11B2 reaction steps. The combination of functional data and computer modelling of CYP11B2 suggests an indirect involvement of r esidue 147 in the regulation of CYP1...

Ngày tải lên: 24/03/2014, 03:21

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Ngày tải lên: 07/08/2014, 20:23

... Swindle R, Yu X, Risser R, Baker RW, Tohen M: Effects of olanzapine alone and olanzapine/fluoxetine combination on health- related quality of life in patients with bipolar depression: secondary analyses ... data are only posi- tive concerning valproate, carbamazepine and lamotri- gine, and only against specific phases of the illness. From a clinical point of view, depression...

Ngày tải lên: 09/08/2014, 01:21