Báo cáo y học: "Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation" pot
Báo cáo y học: "Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation" pot
... days in high-density pellet and hyaluronan-based scaffold cultures. Aiming on a comprehen- sive molecular analysis of the differentiation process of OA chondrocytes, expanded chondrocytes and chondrocytes ... differentiation potential of human OA chondrocytes using microarray technology in order to deter- mine whether OA chondrocytes might possibly be used in se...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "The factor structure of the Strengths and Difficulties Questionnaire (SDQ) in Greek adolescents" potx
... problems scale and had secondary loadings of -0.25 on emotional symptoms scale. The item 'I think before I do things' had loading equal to 0.25 on hyperactivity/inattention scale and a secondary ... divided into two subdimensions (that is, hyperactivity and inattention). This finding may reflect the inability to assess the multidimensional atten- tion deficit hyperactivity d...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: " An exploratory survey of money boys and HIV transmission risk in Jilin Province, PR China" potx
... relatively few had availed themselves of these services. These preliminary findings will be used as a baseline and springboard for continuing study in the Jilin Province money boy community. Even ... "geographic and social elements." These preliminary data suggest that migrants may not necessarily be at the heart of money boy activity in Jilin Province. This finding is...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "A comparative analysis of antibody repertoire against Staphylococcus aureus antigens in Patients with Deep-Seated versus Superficial staphylococcal Infections"
... 64% for assay of Abs against teichoic acid to 72% for assays of antibody to peptidoglycan and α-toxin. The specificity of assays for antibody to cell wall antigens (peptidoglycan and teichoic ... Mollby R. Antibody responses in patients with staphylococcal septicemia against two Staphylococcus aureus fibrinogen binding proteins: clumping factor and an extracellular fibrino...
Ngày tải lên: 02/11/2012, 11:08
Báo cáo Y học: Proteasome-driven turnover of tryptophan hydroxylase is triggered by phosphorylation in RBL2H3 cells, a serotonin producing mast cell line pptx
... ubiquitinylation of TPH protein was involved in the process, presumably by providing the targeting tag. In search for any connection between protein phosphorylation and TPH turnover, we examined ... cell-free proteasome system by protein kinase inhibitors We examined the involvement of TPH phosphorylation in proteasome-driven degradation of the enzyme in vitro.Our system conta...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: The a1b1 contact of human hemoglobin plays a key role in stabilizing the bound dioxygen Further evidence from the iron valency hybrids potx
... stereochemistry of the iron-dioxygen bond in human HbO 2 by single-crystal X-ray analysis. In the a chain, the distance between N e of His (E7) and the terminal oxygen atom (O-2) is found to be 2.7 A Ê , and ... geometry favors a similar hydrogen bond as in oxymyoglobin [29]. In the b chain, however, N e of His (E7) is located further away from both O-2 and O-1 (3.4 and...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "α Does protein kinase R mediate TNF-α- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism" pps
... inhibition of protein synthesis and increased apoptosis, which may also affect cartilage integrity. Increased expression and activation of MMPs, in the absence of a corresponding increase in their inhibitors, ... metalloproteinase (MMP) expression and activation in the medium were analysed by gelatin zymography, proteoglycan release by the dimethylmethylene blue assay, an...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "β Treatment with recombinant interferon-β reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis" ppt
... per injection per mouse), limited hyperplasia of the intimal lining layer and cell infiltration of the synovial sublining were detected and a decrease in bone erosions was observed. (b) Infiltration of ... given daily injections of recombinant mouse IFN-β or saline for 7 days. Disease progression was monitored by visual clinical scoring and measurement of paw swelling. Infla...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis" pptx
... CXCL12 in positioning CXCR4 + T and B cells to distinct synovial microdomains as well as in retaining these cells within the inflamed synovial tis- sue [9]. CXCL12 induces migration of monocytes into ... entry into CD4 + human lymphocytes [4]. Like other members of the chemokine family, CXCL12 may play a role in inflammatory dis- eases. Specifically, there is increasing evidence...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network" pps
... assignment, and the lat- ter lacks physiological system specificity). As seen in Figure 7, the fraction of pairs placed in the categories defined by Goh et al. increases rapidly with increasing score ... class, and are connected in our network. Potentially of more inter- est is the observation that among the 97 potentially associated disease pairs identified by high mutual predi...
Ngày tải lên: 09/08/2014, 20:20