Báo cáo y học: "Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response" potx
... peripheral blood and bone marrow. Rituximab preferentially depletes B cells in peripheral blood (PB) and reduces < /b> activated < /b> B cells in the PB and the bone marrow (BM) of rheumatoid arthritis (RA) patients. ... patients. Favorable response to rituximab therapy < /b> preceded by a decrease in CD19 + CD27 + memory B cells in...
Ngày tải lên: 09/08/2014, 14:22
... pre-germinal center subsets of B cells in PB combined with a reduction in switched memory B cells both in PB and in BM. We showed that the reduction of switched memory B cells (CD27 + IgD - ) ... as compared with rituximab-naïve. The absolute numbers of B cells in the rituximab-treated and rituximab-naïve patients are shown in Table 6....
Ngày tải lên: 09/08/2014, 14:22
... and no response to a course of broad-spectrum antibiotics, and decision by a physician to treat with a full course of antitu- berculosis chemotherapy. EPTB refers to TB of organs other than the ... clinical stages, oral thrush, diar- rhoea, body mass index (BMI), anaemia and total lymphocyte count (TLC) in predicting mortality in both the pre-HAART and the HAART...
Ngày tải lên: 10/08/2014, 05:20
Báo cáo y học: " Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study" potx
... smoking of any intensity has been implicated in muscle wasting [10] by impairing the process of muscle protein synthesis [46]. In con- trast, in the present study, only very heavy smoking appeared to ... is, involuntary loss of fat-free mass [FFM] with a proportional increase of body fat [BF]) in the presence of stable body weight [3,4]. Body composition changes, par...
Ngày tải lên: 09/08/2014, 10:23
báo cáo hóa học: " Methods to recognize work-related cancer in workplaces, the general population, and by experts in the clinic, a Norwegian experience" pptx
... eakness by p oin ting to the lack of defining what doubling of the risk is based on, i.e. what is the reference for doubling. When no level of risk is defined to serve as basis for doubling, the ... synergetic inter- actions, e.g. enabling attribution of the interaction effects of smoking and asbestos in the development of lung can- cers. Also, whenever the contr...
Ngày tải lên: 20/06/2014, 00:20
Báo cáo y học: "Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats"
... using bovine serum albumin as the standard [24]. Levels of lipid peroxidation were measured by the thiobarbituric acid (TBA) reaction according to the method of Ohkawa where the reaction of ... reductase [27]. The oxidation of NADPH had been observed spectrophotometrically at 340 nm, at 37ºC for 5 min. The GSH-Px activity was the slope of the line obtained by pl...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
... receiving combination therapy.< /b> Hepatology 2004;40:1450-8. 15. Crippin JS, McCashland T, Terrault N, Sheiner P, Charlton MR. A pilot study of the tolerability and efficacy of antiviral therapy < /b> in ... costly and has not been studied rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy < /b> although they are no...
Ngày tải lên: 31/10/2012, 17:11
Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... studies have indicated that exogenous DNA becomes concentrated within the posterior part of the nuclear area of the head, the inference being that binding of DNA by the sperm is followed by internalisation ... germline gene therapy < /b> will remain insufficiently safe, excessively inefficient and of inadequate clinical value to permit its use. The widespread avail...
Ngày tải lên: 03/11/2012, 10:01
Báo cáo Y học: Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe pot
... purified by affinity chroma- tography. Activated < /b> Sty1p was detected by inmunoblotting with anti(phospho p38) antibodies. Total Sty1p was determined by inmu- noblotting with anti-Ha antibody as loading ... 360 min, and Sty1p-Ha6H protein was purified by affinity chromatogra- phy employing Ni 2 -nitrilotriacetic acid agarose beads. The activation status of Sty1p was analysed by West...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Double-stranded RNA-activated protein kinase interacts with apoptosis signal-regulating kinase 1 Implications for apoptosis signaling pathways docx
... respectively. For double staining of PKR-KR (c) and ASK1 (d), cells were incubated with both antibodies, followed by RITC-labeled and FITC-labeled secondary antibodies. Cells were observed under ... by Bradford reagent (Bio-Rad Laboratory). RESULTS PKR interacts with ASK1 To investigate whether PKR and ASK1 interact with each other, the localization of PKR and ASK1 w...
Ngày tải lên: 08/03/2014, 09:20