Báo cáo y học: " Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis" pps
Báo cáo y học: " Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis" pps
... antibody condition). Neutralizing antibodies to MHC
Figure 1
Reduced < /b> percentages of CD5
+
B lymphocytes in severe arthritisReduced percentages of CD5
+
B lymphocytes in severe arthritis. Type ... Lundy SK: Killer B lymphocytes: the evidence and the potential.
Inflamm Res 2009 in press.
23. Lundy SK, Boros DL: Fas < /b> ligand-expressing < /b> B- 1a lymphocytes...
Báo cáo y học: "Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis" pps
... Urokinase-
mediated fibrinolysis in the synovial fluid of rheumatoid
arthritis patients may be affected by the inactivation of single
chain urokinase type plasminogen activator by thrombin. Ann
Rheum ... of lymphocytes, uPA was injected
into SCID mice lacking functional T lymphocytes and B
lymphocytes.
Inactivation of uPA with synthetic inhibitor
Synthetic peptide H-
D-Pro-Phe-Arg-ch...
Báo cáo y học: " Intramuscular electroporation with the pro-opiomelanocortin gene in rat adjuvant arthritis" doc
... induced by injecting 0.3 ml of 5.0 mg/ml CFA
(consisting of heat-killed Mycobacterium butyricum in
Introduction
We are now in an era of molecular medicine in which
increasing focus is being placed ... L, Stein C: Interleukin 1
ββ
and corticotropin-
releasing factor inhibit pain by releasing opioids from
immune cells in inflamed tissue. Proc Natl Acad Sci USA
1994, 91:4219-4223.
8. Lu...
Báo cáo y học: "Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis" ppsx
... Melino G, Lee SC, Steinert PM:
Protein unfolding by peptidylarginine deiminase. Substrate
specificity and structural relationships of the natural sub-
strates trichohyalin and filaggrin. J Biol ... probably also anti-Sa antibodies (for references see
[3]). These autoantibodies all recognize epitopes contain-
ing citrulline (the naming of the antibody is simply deter-
mined by the substrate .....
Báo cáo y học: "Regulation of CD154-induced interleukin-12 production in synovial fluid macrophage" pps
... were kindly
provided by Dr P Lane (Birmingham, UK) and have been
previously described [30]. Antihuman CD3 and CD19
microbeads for magnetic cell sorting (MACS) were
obtained from Miltenyi Biotec ... or
BSA = bovine serum albumin; DC = dendritic cell; ELISA = enzyme-linked immunosorbent assay; GM-CSF = granulocyte/macrophage-colony-stim-
ulating factor; IFN = interferon; IL = interleukin; ... w...
Báo cáo y học: "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models" pps
... peripheral blood lympho-
cytes enhance the production of IL-6 and IL-8 by
fibroblast-like synoviocytes, an effect that was blocked by
antibodies against IL-17 [20]. Furthermore, IL-15 produced
by synoviocytes ... and induces proteoglycan breakdown
(Table 2) [44–47]. Furthermore, studies in vitro showed
the induction of metalloproteinases by IL-17 in
synoviocytes and chondrocytes [48–50]....
Báo cáo y học: "Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ" potx
... twice and incubated for 30 min with the indicated
PE- or biotin-conjugated antibodies. For the biotin-conju-
gated antibodies, a third staining step with streptavidin
conjugated with peridinin chlorophyll ... activity was
presented by plotting the percentage of inhibition against
the number of T
reg
cells. As shown in Fig. 4a,c, the patterns
of inhibition in naive IFN-gR KO and wild-type...
Báo cáo y học: " Predictors of infusion reactions during infliximab treatment in patients with arthritis" docx
... antibodies were mostly of IgG
and not of IgE type, despite clinical symptoms indicating type
I allergic reactions. The clinical relevance of measuring these
antibodies is currently being investigated.
In ... factor-α, has been shown to
be effective in treating a variety of inflammatory diseases. In
combination with methotrexate, infliximab provides significant
and sustained improvement...
Báo cáo y học: " High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis" ppsx
... A
α
1
-Antitrypsin PEDF Fibronectin Tetranectin Fibronectin Clustrin H
4
inhibitor
α
1
-Antichymotrypsin Pregnancy zone
protein
Gelsolin α
1
-Acid glycoprotein Fibrinogen S100
Kinninogen Albumin SHAP ... factor binding protein, acid labile subunit
4504781 Inter-alpha (globulin) inhibitor H1
4504783 Inter-alpha (globulin) inhibitor H2
31542984 Inter-alpha (globulin) inhibitor H4 (plasma Kall...
Báo cáo y học: "Hand bone loss as an outcome measure in established rheumatoid arthritis: 2-year observational study comparing cortical and total bone loss" pot
... significantly lower in the group with high
disease activity in both the DXR-BMD and the DXA-BMD
(Table 2).
Table 2
Comparison of the baseline and the change in hand bone mineral density
Disease ... Rosholm A, Hyldstrup L, Backsgaard L, Grunkin M, Thodberg HH:
Estimation of bone mineral density by digital X-ray radiogram-
metry: theoretical background and clinical testing. Osteoporos
Int...
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