Báo cáo y học: " Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis" pps

Báo cáo y học: " Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis" pps

Báo cáo y học: " Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis" pps

... antibody condition). Neutralizing antibodies to MHC Figure 1 Reduced < /b> percentages of CD5 + B lymphocytes in severe arthritisReduced percentages of CD5 + B lymphocytes in severe arthritis. Type ... Lundy SK: Killer B lymphocytes: the evidence and the potential. Inflamm Res 2009 in press. 23. Lundy SK, Boros DL: Fas < /b> ligand-expressing < /b> B- 1a lymphocytes...
Ngày tải lên : 09/08/2014, 14:22
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Báo cáo y học: "Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis" pps

Báo cáo y học: "Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis" pps

... Urokinase- mediated fibrinolysis in the synovial fluid of rheumatoid arthritis patients may be affected by the inactivation of single chain urokinase type plasminogen activator by thrombin. Ann Rheum ... of lymphocytes, uPA was injected into SCID mice lacking functional T lymphocytes and B lymphocytes. Inactivation of uPA with synthetic inhibitor Synthetic peptide H- D-Pro-Phe-Arg-ch...
Ngày tải lên : 09/08/2014, 01:21
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Báo cáo y học: " Intramuscular electroporation with the pro-opiomelanocortin gene in rat adjuvant arthritis" doc

Báo cáo y học: " Intramuscular electroporation with the pro-opiomelanocortin gene in rat adjuvant arthritis" doc

... induced by injecting 0.3 ml of 5.0 mg/ml CFA (consisting of heat-killed Mycobacterium butyricum in Introduction We are now in an era of molecular medicine in which increasing focus is being placed ... L, Stein C: Interleukin 1 ββ and corticotropin- releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue. Proc Natl Acad Sci USA 1994, 91:4219-4223. 8. Lu...
Ngày tải lên : 09/08/2014, 01:23
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Báo cáo y học: "Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis" ppsx

Báo cáo y học: "Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis" ppsx

... Melino G, Lee SC, Steinert PM: Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural sub- strates trichohyalin and filaggrin. J Biol ... probably also anti-Sa antibodies (for references see [3]). These autoantibodies all recognize epitopes contain- ing citrulline (the naming of the antibody is simply deter- mined by the substrate .....
Ngày tải lên : 09/08/2014, 01:23
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Báo cáo y học: "Regulation of CD154-induced interleukin-12 production in synovial fluid macrophage" pps

Báo cáo y học: "Regulation of CD154-induced interleukin-12 production in synovial fluid macrophage" pps

... were kindly provided by Dr P Lane (Birmingham, UK) and have been previously described [30]. Antihuman CD3 and CD19 microbeads for magnetic cell sorting (MACS) were obtained from Miltenyi Biotec ... or BSA = bovine serum albumin; DC = dendritic cell; ELISA = enzyme-linked immunosorbent assay; GM-CSF = granulocyte/macrophage-colony-stim- ulating factor; IFN = interferon; IL = interleukin; ... w...
Ngày tải lên : 09/08/2014, 06:22
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Báo cáo y học: "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models" pps

Báo cáo y học: "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models" pps

... peripheral blood lympho- cytes enhance the production of IL-6 and IL-8 by fibroblast-like synoviocytes, an effect that was blocked by antibodies against IL-17 [20]. Furthermore, IL-15 produced by synoviocytes ... and induces proteoglycan breakdown (Table 2) [44–47]. Furthermore, studies in vitro showed the induction of metalloproteinases by IL-17 in synoviocytes and chondrocytes [48–50]....
Ngày tải lên : 09/08/2014, 06:22
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Báo cáo y học: "Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ" potx

Báo cáo y học: "Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ" potx

... twice and incubated for 30 min with the indicated PE- or biotin-conjugated antibodies. For the biotin-conju- gated antibodies, a third staining step with streptavidin conjugated with peridinin chlorophyll ... activity was presented by plotting the percentage of inhibition against the number of T reg cells. As shown in Fig. 4a,c, the patterns of inhibition in naive IFN-gR KO and wild-type...
Ngày tải lên : 09/08/2014, 06:22
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Báo cáo y học: " Predictors of infusion reactions during infliximab treatment in patients with arthritis" docx

Báo cáo y học: " Predictors of infusion reactions during infliximab treatment in patients with arthritis" docx

... antibodies were mostly of IgG and not of IgE type, despite clinical symptoms indicating type I allergic reactions. The clinical relevance of measuring these antibodies is currently being investigated. In ... factor-α, has been shown to be effective in treating a variety of inflammatory diseases. In combination with methotrexate, infliximab provides significant and sustained improvement...
Ngày tải lên : 09/08/2014, 08:22
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Báo cáo y học: " High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis" ppsx

Báo cáo y học: " High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis" ppsx

... A α 1 -Antitrypsin PEDF Fibronectin Tetranectin Fibronectin Clustrin H 4 inhibitor α 1 -Antichymotrypsin Pregnancy zone protein Gelsolin α 1 -Acid glycoprotein Fibrinogen S100 Kinninogen Albumin SHAP ... factor binding protein, acid labile subunit 4504781 Inter-alpha (globulin) inhibitor H1 4504783 Inter-alpha (globulin) inhibitor H2 31542984 Inter-alpha (globulin) inhibitor H4 (plasma Kall...
Ngày tải lên : 09/08/2014, 10:20
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Báo cáo y học: "Hand bone loss as an outcome measure in established rheumatoid arthritis: 2-year observational study comparing cortical and total bone loss" pot

Báo cáo y học: "Hand bone loss as an outcome measure in established rheumatoid arthritis: 2-year observational study comparing cortical and total bone loss" pot

... significantly lower in the group with high disease activity in both the DXR-BMD and the DXA-BMD (Table 2). Table 2 Comparison of the baseline and the change in hand bone mineral density Disease ... Rosholm A, Hyldstrup L, Backsgaard L, Grunkin M, Thodberg HH: Estimation of bone mineral density by digital X-ray radiogram- metry: theoretical background and clinical testing. Osteoporos Int...
Ngày tải lên : 09/08/2014, 10:20
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