Báo cáo y học: "Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis" docx
Báo cáo y học: "Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis" docx
... drafted
the manuscript and participated in data acquisition. VP partic-
ipated in data acquisition, provided technical assistance and
assisted in analysis and interpretation of data. TT, HJ and IA
participated ... Kubo M, Kiyohara Y, Kato I, Iwamoto H, Nakayama K, Hirakata H,
Fujishima M: Effect of hyperinsulinemia on renal function in a
general Japanese population: the Hisay...
Báo cáo y học: "Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren''''s syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate" pptx
... K, Tagawa Y, Iwakura Y, Kayagaki
N, Kurimoto M, Okamura H, Hada T, Yagita H, Akira S, Nakanishi
K, Higashino K: IL-18 up-regulates perforin-mediated NK activ-
ity without increasing perforin messenger ... expression of IL-18 by CD68
+
macrophages was
observed only within periductal inflammatory foci and in
periacinar macrophages adjacent to focal infiltrates, and
not in isolated macr...
Báo cáo Y học: Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge pptx
... 90) is probably the translational start site
because it is followed by a typical signal peptide motif with
a basic residue (lysine) and a hydrophobic region (rich in
valine and alanine) and matches ... acids) consists of three domains: a
signal peptide (24 amino acids), prodomain (40 amino acids)
andamaturepeptide(21aminoacids).Thegenehastwo
introns and three exons. A TATA...
Báo cáo Y học: Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin a-sarcin potx
... of RNase T1 [23,26,27] and His50 of a- sarcin [20] are
involved in catalysis rather than in substrate binding. The
role of Arg77 has not yet been established as all attempts to
isolate any RNase ... quantitative analysis of the ribonuclease
activity of a- sarcin has been developed by using the
dinucleotide ApA as substrate [18]. Both mutant variants
hydrolysed ApA. They displa...
Báo cáo y học: "The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis" doc
... activity.
Proof -of- concept clinical trial in patients with RA
A proof -of- concept study to explore safety and tolerability,
pharmacokinetics and pharmacodynamics was conducted in
patients with established ... evaluate the safety and tolerability of ACZ885 adminis-
tered as an intravenous infusion. Secondary objectives
included assessment of the preliminary biologic activi...
Báo cáo y học: "SAPHO syndrome: Is a range of pathogen-associated rheumatic diseases extended" ppsx
... Massara A, Cavazzini PL, Trotta F: In SAPHO syndrome anti-
TNF-alpha therapy may induce persistent amelioration of
osteoarticular complaints, but may exacerbate cutaneous
manifestations. Rheumatology ... This is a significant addition to a long
range of publications showing an association of SAPHO with
P. acnes in 42% of patients (Table 1). The activity of SAPHO,
by a...
Báo cáo y học: "The past is a foreign country" docx
... own lab.
• ey have almost certainly never seen anyone blow
glass. In fact, many of them may not know that test
tubes were ever made of anything but plastic.
• ey have always had ... In theirlifetime,noonehaseverpipettedanythingby
mouth.
• DNAsequencing,peptidesynthesis,chemicalanalysis,
and gene synthesis have always been farmed out to
specialty compan...
Báo cáo y học: "Aboriginal status is a prognostic factor for mortality among antiretroviral naïve HIV-positive individuals first initiating HAART" ppt
... were diag-
nosed with AIDS during the HAART era, declines in deaths
were smaller among racial minorities (black, Hispanic,
Asian/Pacific Islanders, American Indian/Alaskan Native)
compared with ... health care disparities exist by
determining what other aspects of being Aboriginal
increase their risk of mortality after initiating HAART can
provide potential targets for intervention...
Tài liệu Báo cáo Y học: Dinucleoside polyphosphates stimulate the primer independent synthesis of poly(A) catalyzed by yeast poly(A) polymerase ppt
... poly (A)
catalyzed by yeast poly (A) polymerase. The relative
activity of diadenosine polyphosphates as effectors of
the poly (A) synthesis was assayed as in Fig. 4, using
0.05 m
M
[a-
32
P]ATP as substrate, ... strain containing a clone of the yeast poly (A)
polymerase gene [6]. In principle, it can be assumed that this
preparation corresponds to pure poly (A) polymerase wit...
Báo cáo y học: "DAS28: a useful instrument to monitor infliximab treatment in patients with rheumatoid arthritis" pps
... opinion-based, approach, with expert
rating (n = 35) of a sample of clinical profiles that were
categorised into remission, low disease activity, moderate
disease activity and high disease activity [7]. Interestingly, ... external criteria for high and low disease activity
to study the validity of the Disease Activity Score and the
DAS28. In a study performed in Italy in the...