Báo cáo y học: "Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia" pot
Báo cáo y học: "Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia" pot
... article Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia Thierry Lequerré 1 *, Carine Bansard 2 *, Olivier Vittecoq 1 , Céline ... functions, and 1 pathway, whereas the 66 genes in cluster 2 clearly involved 6 biological processes, 7 main molecular functions, and 2 pathways (Table 1)....
Ngày tải lên: 09/08/2014, 14:22
Báo cáo Y học: Early growth response-1 gene (Egr-1 ) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro pot
... caused by blood current [7], tissue injury and physical stress in icted by ionizing radiation. Publication of the latter ®nding [8] initiated investigations on how the Egr-1 promoter may be employed ... can be induced by a single dose of 4 Gy. The data presented indicate that radiation induction of the Egr-1 promoter is at least in part mediated by protein factors secreted by U...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Expression and distribution of penaeidin antimicrobial peptides are regulated by haemocyte reactions in microbial challenged shrimp pptx
... circulating haemocyte populations, the percentage of circulating haemocytes expressing and storing penaeidin was further analysed by ISH and ICC, respectively. Circulating haemocytes from five individual ... and analysed by in situ hybridization using antisense pen-3a riboprobes labelled with DIG-UTP and by immunocytochemistry using an anti-penaeidin Ig detected by secondary...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo y học: "Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading" ppt
... possi- bility of studying the early stages of disease progression and the regional pattern of matrix degradation by compar- ing diseased and healthy joints in the same individual. The results presented in ... time). Analysis of tenascinC and the chitinase-like molecules YKL39 and YKL40 was included in the present study because they have been related to human OA [21-23]. Since...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Expression and functional properties of antibodies to tissue inhibitors of metalloproteinases (TIMPs) in rheumatoid arthritis" docx
... certain inflammatory cytokines (IL-6, IL-1β) and by certain growth factors. Extracellularly, TIMPs inhibit MMP activity by forming high- affinity noncovalent complexes with MMPs. The amino-termi- nal ... (32 ng/ml) and activated with 1 mM p-aminophenylmercuric acid. The residual activity of MMP9 was assessed by Biotrak activity assay (Amersham) and registered colorimetrically by...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis" pps
... demonstrated in several other inflam- matory disorders, including systemic lupus erythematosus [48] and chronic active hepatitis [67], and that regulatory pathways in such diseases may also be informative ... phenotypic analy- sis of such membrane DC subsets is now necessary, and will offer insight into the migratory pathway and functional activi- ties of distinct DC subsets in...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Immune complexes from rheumatoid arthritis synovial fluid induce FcγRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-α by peripheral blood mononuclear cells" potx
... therapeutic interventions such as anti-TNF-α and inter- leukin-1 inhibition show the importance of cytokines in RA [16]. Induction of proinflammatory cytokines via cross-linking of FcγR by ICs may be ... point to be optimal for cytokine induction by ICs. Cytokine enzyme-linked immunosorbent assays TNF-α levels were measured using two ELISA systems, namely whole antibodies in matched...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Early and late morbidity and mortality and life expectancy following thoracoscopic talc insufflation for control of malignant pleural effusions: a review of 400 cases" potx
... con- secutive days. Morbidity included all complications occurring during hospitalization only. In- hospital mortality included both those patients who died within first 30 days and those who died ... but during the same hospitalization. Three-month mortality included those patients who died within 90 days after surgery. Follow up was obtained by periodical clinical examination combined...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "Early and mid term mortality after coronary artery bypass grafting in women depends on the surgical protocol: retrospective analysis of 3441 on- and off-pump coronary artery bypass grafting procedures" doc
... 1.7%. Mortality in men was 2.1% after 30 days and 3.7% after one year c) gender specific mortality: 30 days mortality in women was 1.7% using OPCAB and 5.2% using ECC (p = 0.002), one year mortality in ... Lamm Abstract Background: Since 2002 MI and stroke, not cancer, are leading causes of death in women. We studied 30-days and 1 year mortality of 3441 patients undergoing cor...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature" ppsx
... activates the kynurenine pathway, thus chan- neling the available tryptophan to form kynurenine (Kyn), 3-hydroxykynurenine (3HK), and quinolinic acid (QUIN), rather than the serotonin (5-HT). This ... 5 Inflammation activates the kynurenine pathway Some evidence su ggests that proinflammatory cytokines, including TNF-a, induce glial indoleamine 2,3-dioxygenase (IDO). This activates the kynu...
Ngày tải lên: 11/08/2014, 00:23