... Takayama T, Kato J, Yamauchi N, Ko-gawa K, Sakamaki S, Hirayama Y, Kohda K, Niitsu Y. Involve-ment of transforming growth factor-beta and thrombopoietin in the pathogenesis of myelodysplastic ... myelodysplastic syndrome with myelofi-brosis. Leukemia 2005;19:1558-66 21. Hirayama Y, Sakamaki S, Matsunaga T, Kuga T, Kuroda H, Ku-sakabe T, Sasaki K, Fujikawa K, Kato J, Kogawa K, Koyama R, Niitsu Y. ... of the here measured cytokines with levels of anagrelide is understandable, since the varia-tion in maintenance dose was small (mean daily dose at 6 months 2.3±0.2 mg) and the number of patients...