Báo cáo y học: "Anti-C1q antibodies antedate patent active glomerulonephritis in patients with systemic lupus erythematosus" pot

... between the Systemic Lupus Erythematosus Disease Activ- ity Index and anti-C1q and anti-dsDNA titers. Patients included those with active systemic lupus erythematosus (SLE) with (n = 15) and with- out ... eight (62%) nephritis patients in our series, 30% in the study by Moroni and colleagues [32], and 47% in the study by Fang and col- leagues [29]). In our study, t...

Ngày tải lên: 09/08/2014, 14:21

... events in this population (27). In a re- cent study C-reactive protein and low albumin has been shown to be the predictor of morbidity and mor- tality in CKD 3-5 patients in Spain (31). Our study ... malnutrion and inflammation in ESRD patients (25, 26). Hypoalbuminemia, a marker of malnutrition and underlying inflammation has come up as a powerful predictor of mortality i...

Ngày tải lên: 03/11/2012, 11:52

... phagocyte activity may be involved in the mechanism of action of anti-TNF-α therapy [9]. BSA = bovine serum albumin; C3Zy = C3-coated zymosan; FMLP = N-formyl-methionyl-leucyl-phenylalanine; mAb ... observed in patients during adalimu- mab therapy does not explain the decreased influx of neu- trophils into synovial joints previously observed in RA patients during anti-TNF-α therapy...

Ngày tải lên: 09/08/2014, 06:22

... likely not reflect the true ratio between acute and delayed reactions involving the skin, since acute reactions with skin involvement occur in 4% of the infusions and are usually treated by the ... nature of clinically important dermatological conditions during TNF-α- blocking therapy in patients with rheumatoid arthritis (RA). RA patients starting on TNF-α-blocking therapy were p...

Ngày tải lên: 09/08/2014, 06:22

... laboratory and clinical parame-ters in patients with systemic lupus erythematosusEffect of Rituximab therapy on different laboratory and clinical parame- ters in patients with systemic lupus erythematosus. ... Rituximab (anti-CD20) therapy in patients with lupus nephritis. In an open clinical trial, 22 patients with active systemic lupus erythematosis a...

Ngày tải lên: 09/08/2014, 08:22

... (hnRNP)-A2 in systemic lupus erythematosus (SLE) patients and healthy controls. Proliferation was measured by [ 3 H]thymidine incorporation in PBMCs of 35 SLE patients and 21 controls in the presence ... University Medicine Berlin, Department of Rheumatology and Clinical Immunology, Humboldt University and Free University, Berlin, Germany 4 Institute of Pathophysiology, Medical...

Ngày tải lên: 09/08/2014, 08:22

... neutrophil and lymphocyte apoptosis in patients with very early inflammatory arthritisSynovial fluid neutrophil and lymphocyte apoptosis in patients with very early inflammatory arthritis. (a) Synovial ... clinical presentation in patients with very early inflammatory arthritis divided according to outcome. (b) Synovial fluid lymphocyte apoptosis at clinical pres- entation...

Ngày tải lên: 09/08/2014, 08:22

... TNF-a inhibition may restore this cou- pling of destruction with formation. Early changes in bone markers were previously observed in a study conducted in 68 RA patients who were treated with inf- liximab ... infliximab on BMD in RA patients and to compare the findings with those in a control group. The major finding of our study is that bone loss was prevented in RA pa...

Ngày tải lên: 09/08/2014, 10:20

... reduced in SLE patients and functionality is partly impaired. We suggest these findings reflect increased susceptibility to apoptosis of CPCs from SLE patients. Introduction Systemic lupus erythematosus ... L, D'Agostino RB, Kuller LH: Age-specific incidence rates of myocardial infarction and angina in women with sys- temic lupus erythematosus: comparison with the Frami...

Ngày tải lên: 09/08/2014, 10:20

... in vivo and was safely administered to patients with SLE. These findings supported the initiation of phase II studies investigating the safety and clinical activity of belimumab in patients with ... (11) ANA, antinuclear antibody; SLE, systemic lupus erythematosus; SELENA, Safety of Estrogens in Lupus Erythematosus National Assessment; SLEDAI, Systemic Lupus Erythemat...

Ngày tải lên: 09/08/2014, 13:21