Báo cáo y học: "Reduced rates of primary joint replacement for osteoarthritis in Italian and Greek migrants to Australia: the Melbourne Collaborative Cohort Study" doc
... separately. Moreover, the reduced rate was observed for joint replacements performed Table 2 Risk factors for primary joint (hip and knee) replacement for osteoarthritis Primary joint replacement Primary ... participated in the design of the study and the acquisition of data and reviewed the manuscript. SG participated in the design of the...
Ngày tải lên: 09/08/2014, 14:21
... by The Arthritis Centre of Excellence of the University of Toronto and is the recipient of The Arthritis Society/CIHR Investigator Award. Dr Fortin is funded by an Investigator Award from The ... coordinated the acquisition of laboratory samples, clinical data acquisition, and entry of clinical and laboratory variables into the database. TJH, CMTG, and GSC p...
Ngày tải lên: 09/08/2014, 13:21
... silencing display greater phenotypic noise. Results In the experiments described here the colonies were maintained by backcrossing to the inbred congenic strain, in some cases C57BL/6 and in other ... Reduction of genetic variability, by using inbred strains, and reduction of environmental variability, by standardized husbandry, did not significantly reduce the range...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: "Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic nois" pdf
... husbandry, did not significantly reduce the range of random pheno- typic variability. Simil arly, moving the animal s into the wild to increase environmental variability did not increase random ... heterozygotes to define the linked interval. Estimating the prob ability of ENU-induced coding mutations was performed using for- mulas accessible on the ‘enuMutRat on zeon’ w...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt
... 2002 20 lL of the enzyme/inhibitor mixture to 180 lLof substrate (4NPGlc), incubating for 30 min at 37 °C, and measuring the rel ease of 4NP. Protein assays and protein sequencing Total protein in crude ... able to hydrolyse glycosides to release the (bioactive) aglycone in the small intestine. The purpose of this study was to determine whether the human cy...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Functional epitope of common c chain for interleukin-4 binding ppt
... methods applied. Therefore, further studies will be required to determine w hether Y1 03 and other residues i dentified in the present study are also involved in binding of other c c -dependent cytokines. The ... system and possibly providing a paradigm for other c c -dependent cytokine receptor systems, but also for delineating the molecular pathology of XSCID. So far...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Bromoperoxidase activity of vanadate-substituted acid phosphatases from Shigella flexneri and Salmonella enterica ser. typhimurium doc
... likely that phosphate binds at the active site of the enzyme and prevents binding of the vanadate. Therefore phosphate should be absent in the assay. To induce the brominating activity of PhoN-Sf, ... m M Br – and 2 m M H 2 O 2 on a Cary 50 [23]. The kinetic parameters were determined using the ENZYMEKINETICS program from Trinity Software. Assay of PhoN-Se bromin...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Heterologous expression of a Rauvolfia cDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids pot
... results in the same end product cathenamine and involves the same intermediate 4,21-dehydrocorynantheine aldehyde. The formation of the 3-isocorreantine A after hydrolysis of dolichantoside is an indication ... gives rise to the end product cathenamine and involves 4,21-dehydrocory- nantheine aldehyde as an intermediate. The enzymatic hydrolysis of dolichantoside (Nb...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "Ocular Manifestations of Rickettsiosis: 1. Mediterranean Spotted Fever: laboratory analysis and case reports" potx
... it may also be acquired through the skin or eye when the ticks are crushed. The disease is endemic during the spring and summer in most of the regions bordering on the Mediterranean and Black ... Black seas, in Kenya and other parts of central Africa, South Africa, and certain parts of India. MSF varies in severity but is seldom fatal. The incubation peri...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo y học: "Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage" docx
... San Leandro, CA, USA), and the inten- sity of the L-PGDS bands was normalized by dividing them by the intensity of the β-actin band of the corresponding sample. 11β-PGF 2 α and PGD 2 assays The ... in many pathologies. The enhanced expression of L-PGDS in the superficial and middle zones of cartilage could potentially be due to the increased level of...
Ngày tải lên: 09/08/2014, 01:22