Báo cáo y học: "Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor" potx

... in < /b> increased numbers in < /b> patients with RA [19]. As a result, post-switch memory < /b> B cells accumulate not only in < /b> the synovium but also in < /b> the blood < /b> of patients with long-standing RA. The human memory < /b> ... article Alterations in < /b> peripheral < /b> blood < /b> memory < /b> B cells in < /b> patients with active...

Ngày tải lên: 09/08/2014, 14:21

... production by monocytes via CD40-CD40 ligand interaction. Eur J Immunol 1995;25:1125–8. 12. Jirapongsananuruk O, Leung DY. Clinical application of cytokines: new direction in < /b> the therapy of atopic ... involved in < /b> the generation of polarized effector cells. 4 DCs have a major influence on the pattern of Th1/Th2 polarization by releasing cytokines, especially int...

Ngày tải lên: 08/08/2014, 21:20

... when compared with a single cytokine inhibition. Conclusion These findings indicate that interactions between cyto- kines have to be considered, regarding their mode of action and their contribution ... the functional consequences of cytokine treatment on OPG production by RA synoviocytes. The more interesting contribution is the demonstration of synergistic interactions bet...

Ngày tải lên: 09/08/2014, 01:23

... administration of a single cytokine is not representative for skewing of an immune response in < /b> which multiple cytokines are involved. HSPs probably not only increase IL-10 production by T cells, but ... controversial. On one hand, TLR stimulation on DCs can enhance IL-10 production by them, and thereby induction of Tregs (Figure 2a). On the other hand, stimulation of...

Ngày tải lên: 09/08/2014, 14:20

... usually assessed jointly, the elimination of any one of them would not increase the feasibility of calculating the score. In < /b> a cross-sectional analysis of a large number of patients, the CDAI not only ... not be intuitive to eliminate any one of them, especially as, in < /b> contrast to the APRs, they do not correlate with struc- tural damage independently....

Ngày tải lên: 09/08/2014, 06:22

... disease. The clinical course of patients with advanced cirrhosis is often compli- cated by a number of important sequelae that are in-< /b> dependent of the etiology of the underlying liver dis- ease. These ... precapillary connections [24]. No any treatment is clinically useful, thus, at present the only treatment resulting to the resolution of the syndrome...

Ngày tải lên: 08/08/2014, 18:20

... classical pathway, hypoactivation of the complement alternative pathway and overactivation of the terminal pathway. Conclusions: The results obtained provide further evidence on the involvement of the inflammatory ... informed consents to provide 5 ml of venous blood < /b> for the study, and the study was approved by the Ethical CommitteeoftheInstituteof Molecular B...

Ngày tải lên: 08/08/2014, 21:20

... metabolism and are regulated in < /b> bone by pro-inflammatory cytokines. The objective of this study was to investigate the role of HNE in < /b> OA osteoblast metabolism by determining its effect on the production of ... studies suggesting that HNE exerts its inhibitory action at the IKKα level or upstream, thereby affecting subsequent I B phosphorylation/proteoly- sis...

Ngày tải lên: 09/08/2014, 08:22

... Receptor Binding Studies Using [ 3 H] 5-Hydroxytryptamine 5-HT receptor assay was done using [ 3 H] 5-hydroxy- tryptamine binding in < /b> crude synaptic membrane pre- parations of hippocampus by the modified ... After overnight incubation, the brain slices were rinsed with PBST and then incubated with appropriate secondary anti- body of either FITC (No: AB7130F, Chemicon, dilute...

Ngày tải lên: 10/08/2014, 05:21

... levels of retinol, tocopherol, cholecalcifer- ol, Fe and Cu may be lower whereas serum Pb con- centrations may be increased in < /b> patients with CAD. These findings need to be further investigated in < /b> ... have produced con- flicting results; these may in < /b> part be explained by the use of nonspesific measures of body Fe stores, such as serum transferrin (16-19)....

Ngày tải lên: 25/10/2012, 10:51