... of RA.IntroductionSynovial tissue from healthy individuals consists of a singlelayer of synovial cells without infiltration of inflammatory cells. In rheumatoid synovial tissue, lymphocytes ... Arthritis Res Ther 2004, 6:R120-R128.19. Min SY, Hwang SY, Jung YO, Jeong J, Park SH, Cho CS, Kim HY,Kim WU: Increase of cyclooxygenase-2 expression by inter-leukin 15 in rheumatoid synoviocytes. ... significantly impaired the SF-mediated proliferationefficacy of FLSs (Figure 4b). These results suggest that the GM-CSF in SF has a key role in the hyperproliferation of RAFLSs, further supporting the...