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Báo cáo y học: "AIT test has no problem in the detection of anti-ribosomal P" ppsx

Báo cáo y học:

Báo cáo y học: "AIT test has no problem in the detection of anti-ribosomal P" ppsx

... qualitycontrol program run by the Korean Society of LaboratoryMedicine [3]. In 1999 and 2007, reports of antinuclearantibody test using the IT-1 cell line on 208 and 588systemic lupus erythematosus (SLE) ... criteria of SLE have been recently suggested, like Mahler andLetterAIT test has no problem in the detection of anti-ribosomal PLa-He Jearn and Think-You KimDepartment of Early Arthritis/Laboratory ... respectively,showed a 100% positive rate that proved an exceptionalimprovement in the test performance [4,5]. Furthermore, the AIT test can indirectly help in the diagnosis of SLE using the microtubule...
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Báo cáo y học:

Báo cáo y học: " AIT test has no problem in the detection of anti-ribosomal P – authors’ response" docx

... antibodies.A systematic study is mandatory to compare the sensitivityand specificity of the AIT test for the detection of anti-Rib-Pantibodies and other antibody specificities using a variety of contemporary ... and/ornucleolar staining pattern [2]. Despite the clearance of the AIT test by the South Korea Food and Drug Administration, to the best of our knowledge this test is not widely used as ascreening method ... to the anti-Rib-P system, Bonfa andcolleagues clearly demonstrated that immunodiffusion has very low sensitivity for the detection of anti-Rib-P antibodies[3]. In their study, only 14% of anti-Rib-P-positive...
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Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx

... & Therapy Vol 6 No 3 Haringman and TakRecently, there has been an enormous upsurge in investigations on the potential of chemokine blockade as anovel therapeutic strategy to inhibit inflammation ... selectively [20]. In that study a highly specific neutralizing antibody againstIL-8 was administered in several types of acuteinflammatory disease, including lipopolysaccharide/IL-1induced arthritis. ... the CCR1-positive cells are macrophages, which play a keyrole in synovial inflammation. The rationale for the clinicalstudy was supported by interesting properties of the novelsmall-molecular-weight CCR1...
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Báo cáo y học: "What do biomarkers tell us about the pathogenesis of ankylosing spondylitis" ppsx

... MRIexamination even shows that while inflammatory changes in the spine predict the development of new syndesmophytes,complete resolution of inflammation at a vertebral cornerfollowing the institution ... pathogenesis of ankylosing spondylitis?Walter P MaksymowychDepartment of Medicine, University of Alberta, Edmonton, Alberta T6G 2S2 CanadaCorresponding author: Walter P Maksymowych, walter.maksymowych@ualberta.caSee ... cornerfollowing the institution of anti-TNF therapy does not prevent the development of new syndesmophytes [10]. On the contrary, it appears that new syndesmophytes are even morelikely to develop at those...
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Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt

... processesunderlying RP and PAH contribute to the familiar pattern of skin, renal and gastrointestinal pathology. The emergence of effective and conveniently administered therapy for PAHincreases the importance ... at1 year and 2 years of 96% and 89% compared withViewpointCold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertensionFrances C HallUniversity of ... vasculopathy of SScl mayalso be modifiable. In the characteristic microangiopathy of SScl, luminalnarrowing results from a combination of intimal proliferation,medial hypertrophy and adventitial...
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Báo cáo y học: "MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis" pps

... of RA.IntroductionSynovial tissue from healthy individuals consists of a singlelayer of synovial cells without infiltration of inflammatory cells. In rheumatoid synovial tissue, lymphocytes ... Arthritis Res Ther 2004, 6:R120-R128.19. Min SY, Hwang SY, Jung YO, Jeong J, Park SH, Cho CS, Kim HY,Kim WU: Increase of cyclooxygenase-2 expression by inter-leukin 15 in rheumatoid synoviocytes. ... significantly impaired the SF-mediated proliferationefficacy of FLSs (Figure 4b). These results suggest that the GM-CSF in SF has a key role in the hyperproliferation of RAFLSs, further supporting the...
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Báo cáo y học: "Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity" pdf

... repair capacity. The current study has some important limitations, whichinclude the use of young bovine cartilage and the use of the synchronous cultures. The synchronous induction of cartilagedegradation ... measuring sulphatedglycosaminoglycans (S-GAGs) are available, these assays donot distinguish between synthesis and degradation of the pro-teoglycans [19]. Furthermore, they do not distinguish ... type II synthesis, whereas proteoglycan synthesis wasstrongly attenuated. In contrast, at the time of maximal aggre-canase activity, the proteoglycan loss was fully reversible.These findings...
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Báo cáo y học:

Báo cáo y học: "Mechanical complications and reconstruction strategies at the site of hip spacer implantation"

... treatment of the infection source by locally reaching high antibiotic levels, (ii) maintance of joint mobility, (iii) limitation of scar formation, (iv) absence of soft tissue contraction (usually ... facilitates the prosthesis reimplan-tation regarding shorter surgery time, less blood loss and no need for femoral exposure. The remaining intrapelvic cement has no disadvantage regarding the infection ... onto the proximal femur and evaluate the effect of a metallic endo-skeleton on the pharmacokinetic properties of the interim prosthesis. Conflict of Interest The authors have declared that no...
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Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx

Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx

... alanine (6.5%). Thus, the alanine and glycinecontent of WSM was rather similar to that of EDTA-IM. In spite of the presence of mineral, it was possible to analyze the amino acid composition of the ... being quite glutamic acid-rich in WSM.Glycosaminoglycan analysisGlycosaminoglycans are highly negatively charged because of the presence of sulfate ester and/or carboxyl groups.Therefore, they ... revealed the predominance of two amino acids: alanine (39.2%) andglycine (30%). Interestingly, the proportions are very similarto those found in WSM for alanine and glycine.Curiously, the presence...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx

Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx

... mobility (lane 3, *)occurring within the ascomplex. As the as1-Cas and as2-Casoverlap in the same zone of the gel, the as1-Cas composition of each phenotype was analysed by immunostaining ... the intensity of the isoelectrofocusing bands and the surface of the relevant peak in RP-HPLC.Fig. 6. Nucleotide sequence of the expected as1-CasM cDNA obtained by genomic e xon sequencing ... 3 in the 9thexon of the A alle le, which is deleted in the F allele, ismutatedtoTintheMallele, giving rise to a Ser fi Leusubstitution.Analysis of the intronic flanking sequences The flanking...
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