Báo cáo y học: "Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as control" doc

... 3 Research article Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls Klaus Stark 1 , ... genetic association in a RA-OA case-control set- ting in a Slovak population. Materials and methods Study participants A total of 520 Slovak indi...

Ngày tải lên: 09/08/2014, 14:20

... the reported association of the MHC2TA -16 8A& gt;G polymor- phism with RA in a group of 373 Austrian Caucasian RA cases and 373 healthy Austrian Caucasian controls. Materials and methods A total of 362 RA ... by examining the -16 8A& gt;G polymorphism in an Austrian case–control study. Three hundred and sixty-two unrelated RA cases and 351 sex-matched and age-matched controls...

Ngày tải lên: 09/08/2014, 08:22

... inter-examinator variability, all anthropometrics measures were obtained by a single trained examiner. Body mass, height and waist circumference were assessed. Body Mass Index was calculated ... independently of age [12-16]. Increasing age is associated with a greater prevalence of impaired glucose tolerance and T2D [17, 18]. There is an interaction of many factors associa...

Ngày tải lên: 08/08/2014, 16:23

... colinearity with partner’s HCV status. Initial multivariate model included all variables. The final model retained variables “Marital status”, “history of STI” and “Marital status” because of confounding ... socio-demographic characteristics and risk factors. Data are subse quently entered into HIV/ AIDS electronic database operated by the IDACIRC. The database contains information on a...

Ngày tải lên: 10/08/2014, 05:22

... Russian Federation. The extent of osteoarthritis was determined by analyzing plain hand radiographs. The outcome of a principal component analysis of osteoarthritis scores of a total of 28 joints ... of calcium-containing crystals in articular cartilage observed in these families is a common finding that is fre- quently associated with advanced OA. In contrast...

Ngày tải lên: 09/08/2014, 06:23

... oste- oarthritis. Nat Genet 2007, 39:529-533. 6. Kizawa H, Kou I, Iida A, Sudo A, Miyamoto Y, Fukuda A, Mabuchi A, Kotani A, Kawakami A, Yamamoto S, Uchida A, Nakamura K, Notoya K, Nakamura Y, Ikegawa ... in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis Dongquan Shi 1,2 , Takahiro Nakamura...

Ngày tải lên: 09/08/2014, 10:23

... Tsukahara S, Kawaguchi Y, Terai C, Hara M, Tomatsu T, Yamanaka H, Horiuchi T, Tao K, Yas- utomo K, Hamada D, Yasui N, Inoue H, Itakura M, Okamoto H, Kamatani N, Momohara S: Association of STAT4 with ... USA), and association was examined in 308 SLE patients and 306 healthy individuals. Statistical analysis Association of each SNP was analyzed by chi-square test. Because of the r...

Ngày tải lên: 09/08/2014, 13:22

... from patients at regula r intervals as follows: the plasma crea- tine was measured by UniCel DxC 800 PRO Sync hron clinical chemistry analyzer ( Beckman Coulter Inc., Brea, CA) using manufacturer’s ... leukocytes using a genomic DNA kit (Qiagen) a ccording to the manufacturer’s instructions. Genotyping was achieved using an assay-on-demand allelic discrimination assay and detect...

Ngày tải lên: 10/08/2014, 05:21

... records and/or self-reported questionnaire and each case was validated by cardiac ultrasound and/or electrocardiographic examinations or by coronary angiography. Table 1: Patient characteristics. ... counting and compared using the א² test. The data was analysed using SPSS 12.0 software. The association between the +294T/C polymorphism and serum lipids, coronary heart disease, and...

Ngày tải lên: 31/10/2012, 17:03

... Island, NY, USA), provided LipofectAMINE PLUS reagent, penicillin and streptomycin; castanospermine was obtained from Alexis (San Diego, CA, USA); protease inhibitor cocktail was obtained from Roche ... These data suggest that BiP has a negative effect on the folding of TSHR. The interaction of this receptor with BiP leads to an increase in the degradation of TSHR and also to a...

Ngày tải lên: 31/03/2014, 08:20