Báo cáo y học: "Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration" ppt

... 2002 Double-stranded RNA-activated protein kinase interacts with apoptosis signal-regulating kinase 1 Implications for apoptosis signaling pathways Takenori Takizawa 1 , Chizuru Tatematsu 1 and Yoshinobu ... S., Kirchhoff,S.,Hauser,H.,Decker,T.&Koromilas,A.E. (19 97) Physical association between STAT1 and the interferon-inducible protein kinase PKR an...

Ngày tải lên: 08/03/2014, 09:20

... uniquely expressed genes. Selection of hypervariable (HV) genes To have an opportunity to evaluate inhomogeneity in gene expression variability, it is necessary to normalize this vari- ability to ... article Novel approaches to gene expression analysis of active polyarticular juvenile rheumatoid arthritis James N Jarvis* 1 , Igor Dozmorov* 2 , Kaiyu Jiang 1 ,...

Ngày tải lên: 09/08/2014, 01:23

... on destruction. Conclusions Mutations of the p53 tumor suppressor gene were present in synoviocytes isolated from both erosion and non -erosion sites in longstanding RA. Clusters of mutations can occur in RA synovium, but the ... non -erosion sites were examined. Ten erosion FLS lines and nine non -erosion FLS lines were established from nine patients with RA...

Ngày tải lên: 09/08/2014, 06:22

... 'sympathetically maintained pain' [5]. Naturally occurring sympathetic neurotransmitters are cate- cholamines known as norepinephrine, epinephrine, and dopamine. All three substances act within the ... frequent COMT gene haplotypes strongly associated with sensitivity to experimental pain and induction of a more defective COMT enzyme. Healthy females with the 'high...

Ngày tải lên: 09/08/2014, 10:21

... antigen-specific T-cell repertoire is spontaneously enriched in synovial fluid. The specific T-cell repertoire in the periphery was modulated by therapy and decreased with the remission of the disease. ... prominent role in joint inflammation. The T-cell mediated self-reactivity CDR3: third complementarity-determining region; CFSE: carboxyfluorescein diacetate succinim...

Ngày tải lên: 09/08/2014, 13:22

... concentrations of norepinephrine in the tissue (nerve fiber loss) [1,5]. Minor stress and probably also Review Insights into endocrine-immunological disturbances in autoimmunity and their impact on treatment Maurizio ... tolerance and efficacy in autoimmune rheumatic diseases [16]. Insights into neurohormonal effects of melatonin in autoimmunity MLT is an i...

Ngày tải lên: 09/08/2014, 13:22

... gene therapy for the inhibition of intervertebral disc degeneration. Int J Exp Pathol 2006, 87:17-28. 7. Le Maitre CL, Freemont AJ, Hoyland JA: The role of interleukin-1 in the pathogenesis of ... AJ: Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human interverte- bral disc: an...

Ngày tải lên: 09/08/2014, 14:20

... PCR was carried out with a forward primer, FP1: 5-CACCGGCTTAGGCATCTCCTATGG- CAGGAAGAA-3 and reverse primer RP1: 5- TAACCCTTCCAGGTACCCCCTTTTCTTTTA-3. The nested PCR was carried out with the forward ... 5′-tgtaaaacgacggccagtCTGTTAAATGGCAGTC- TAGC and reverse primer, RP2: 5′-caggaaacagctatgacc- CACTTCTCCAATTGTCCCTCA. Primers FP2 and RP2 contain the M13 universal primer sequence (lower case), whi...

Ngày tải lên: 10/08/2014, 05:21

... this article as: Bosch et al.: Continuing or adding IL-2 in patients treated with antiretroviral therapy (ACTG Protocol A5 051, a rollover trial of ACTG Protocol A3 28). AIDS Research and Therapy ... therapy (ACTG Protocol A5 051, a rollover trial of ACTG Protocol A3 28) Ronald J Bosch 1* , Richard B Pollard 2 , Alan Landay 3...

Ngày tải lên: 10/08/2014, 05:21

... work is properly cited. Research article Post-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long-acting injection, I: analysis of cases Holland ... Stickelmeyer M, Sorsaburu S, Watson SB, Mitchell MI: Post-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine...

Ngày tải lên: 11/08/2014, 16:22

... properly cited. Research article Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes Ben ... Transcriptional profiling of bovine inter- vertebral disc cells: implications for identification of normal and degenerate human in...

Ngày tải lên: 12/08/2014, 11:23

... was Distribution of keratin IFs and HSP70i in hepatocytes from control and GF-fed C3H miceFigure 2 Distribution of keratin IFs and HSP70i in hepatocytes from control and GF-fed C3H mice. A, C, E keratin IFs; ... of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H miceFigure 4 Distribution of keratin IFs and K8 pS436 in hepatocyte...

Ngày tải lên: 13/08/2014, 13:20

... genesGene ontology analysis results for the top 200 prognostic genes.Click here for fileAdditional data file 8Gene ontology analysis results for the top 200 prognostic genesGene ontology analysis ... optimal classifier performed independently of the ER gene expression level (data not shown) in ER+ tumors. The overlap of the 52 -gene classifier with either van't Vee...

Ngày tải lên: 14/08/2014, 17:22

... Genome Biology 2008, 9:R181 Open Access 2008Maet al.Volume 9, Issue 12, Article R181 Research Male reproductive development: gene expression profiling of maize anther and pollen ontogeny Jiong Ma Ô , ... meiosis and later pollen dispersal. Synchronous development of many anthers per tassel and within each anther facilitates dissection of carefully staged mai...

Ngày tải lên: 14/08/2014, 21:20