Báo cáo y học: "Complex genetic association of 6q23 with autoimmune rheumatic conditions" docx

... some of which may arise from low-frequency alleles. Complementary functional studies should lead to a full understanding of the biological basis of the genetic associations of this region with autoimmune rheumatic ... RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, Graham DC, Wong AK, Vyse TJ, Daly MJ, Altshuler D, Moser KL, Gaffney PM: Genetic variants near TNFAIP3 on 6q23...

Ngày tải lên: 09/08/2014, 14:20

... Y, Botton E, Mary JY, Le Goff P, Youinou P: Ability of the American College of Rheumatology 1987 criteria to predict rheumatoid arthritis in patients with early arthritis and classification of ... PPV of one of these cut-off values is statistically superior to the others. The specificity was signif- icantly different between the cut-off of two or more erosive joints (89%) compa...

Ngày tải lên: 09/08/2014, 14:22

... [4]. Drosophila embryonic development is particularly amenable to analysis by both in situ hybridization and microarray analysis. Large numbers of approximately staged embryos enable the isolation of sufficient ... specify the correct tissue-specific expression of genes. Analyses of yeast had shown a fairly simple hierarchical regulatory architecture, in which master regulators dri...

Ngày tải lên: 09/08/2014, 20:21

... identify occult FAP in young patients with thyroid tumors [4]. Recently Xu B [5] suggested that accumulation of mutant β-catenin contributes to the development of C-MV of PTC. A handful of sporadic ... 2 yr Perrier et al.[10] 11/12 cases F/15- 61 yrs Yes Bilateral : 5 18 mm (0.2-5 cm) multicentric :8 2 cases with LN met’s All ND 5 Total thyroidectomy 5 near total t...

Ngày tải lên: 03/11/2012, 10:05

... studies of cytochrome bo 3 . MATERIALS AND METHODS Synthesis of the HPBC-perchlorate salt Solutions were prepared of 2.33 g of Co(NO 3 ) 2 Æ6H 2 Oin 20 mL of water and of 2.5 g of 2,2¢-bipyridine ... Universita ¨ tGo ¨ ttingen, Germany), DIAMOND for the graphic display of structures (K. Brandenburg, Univer- sita ¨ t Freiburg, Germany). Determination of quantum yield of ox...

Ngày tải lên: 21/02/2014, 15:20

... that polypeptide amounts of Fig. 3. Effe cts of vanadate and erythrosin B on the substrate dependence of H + -ATPase hydrolytic activity from U. maydis plasma membrane vesicles. Models of inhibition. ... yeast enzyme, h ave been shown to be the result of displacement of the autoinhibitory C-terminal domain of the protein [13], probably through phosphorylation by Ptk2p [14]. S imi...

Ngày tải lên: 08/03/2014, 22:20

... Central Page 1 of 4 (page number not for citation purposes) Annals of General Hospital Psychiatry Open Access Review Psychophysiology and psychoacoustics of music: Perception of complex sound ... Physics of simple sound can be described as a function of frequency, amplitude and phase. Psychology of sound, also termed psychoacoustics, has its own distinct elements of pitch, i...

Ngày tải lên: 08/08/2014, 20:23

... systematic genetic analysis (SGA) [5,6] and dSLAM (heterozygote diploid-based synthetic lethality analy- sis with microarrays) [7,8], have made it possible to screen for negative GIs, namely synthetic ... predicted many positive GIs (Figure 8d). Consistent with the results of Bandyopadhyay et al. [17], in six out of the seven complexes in which the majority of the negative interac...

Ngày tải lên: 09/08/2014, 20:21

... group (10 days) was generally consistent with that in previous cohort studies of patients with VAP (10 to 14 days) [1,23]. Simi- larly, duration of hospitalization (26 days) was within the range ... design, analysis of results, interpretation of findings, and drafting of the paper. Independent statistical analysis. The accuracy of the data analysis was inde- pendently verifie...

Ngày tải lên: 25/10/2012, 10:02

... ampli- fied cryptate emission (TRACE) technology assay (PCT Kryptor ® , B.R.A.H.M.S. AG, Hennigsdorf, Germany). The assay has a detection limit of 0.02 μg/L and functional assay sensitivity of 0.06 ... 3 of 14 distress syndrome within 30 days following inclusion. The secondary endpoint was overall survival within 30 days following study inclusion. Outcomes were assessed during hospital...

Ngày tải lên: 25/10/2012, 10:02