Báo cáo y học: "Colony variability under the spotlight in animal models of arthritis" pps

... distinct colonies of the susceptible mouse strain BALB/c. Although induction of disease by the usual immunisation regime did not reveal any differences in incidence and severity, the sub-lines of ... of the research was to compare the incidence and severity of PGIA and proteoglycan-induced spondylitis and to determine expression patterns of a panel of relevant genes...

Ngày tải lên: 09/08/2014, 14:20

... [13]. Alterations in the citrullination of myelin proteins and autoim- mune targeting of citrullinated myelin proteins have been observed in MS. Myelin basic protein (MBP) is partially citrull- inated (C8 isoform) ... using myelin and synovial antigen arrays. (a, b) Synovial and (d, e) myelin arrays were produced by printing synovial and myelin peptides and proteins in ordered a...

Ngày tải lên: 09/08/2014, 13:22

... in order to assess the well-being of patients receiving antipsychotic medication independent of the improvement in their psychotic symptoms. The current study reports on the reliability and the ... treated either with FGAs or SGAs showed that both quality of life and symptom severity improved over the study period, regard- less of the antipsychotic taken, indicating...

Ngày tải lên: 08/08/2014, 23:21

... give a dose increase of infliximab could happen only at one time point. This difference in study design and therapy may explain why in the present study the AUC of DAS28 is smaller than in other studies ... remaining disease activity in daily prac- tice (and in clinical trials). The aim of the present analyses was to evaluate whether the decision to increase the do...

Ngày tải lên: 09/08/2014, 06:23

... clinical trials. Interleukin-4 and Interleukin-13 Inhibition Interleukin-4 (IL-4) and Interleukin-13 (IL-13) are cytokines that play a role in allergic inflammation by inducing Th2 responses. Interleukin-4Rα ... authors concluded that there may be an increased risk of anaphy- laxis in asthmatic patients that may be dependent on the severity of asthma. Another variable and difficulty...

Ngày tải lên: 08/08/2014, 21:20

... different times of the night. These findings are hypothesized to be the result of a change in the sensitivity of the melanopsin-expressing retinal ganglion cells to light during the night. Background It ... (rPA) was obtained by dividing the pupil area by the iris area. Only the rPA values obtained during the light exposure periods were analyzed. All of the rPA v...

Ngày tải lên: 10/08/2014, 09:20

... phenotype. The myocardium proliferates to a normal number of cells, but instead of building into concentric layers to form the walls of the heart, the myocardial cells form into a single layer, ... mitogen-activated protein kinas- es (see the accompanying minireview [11] on the bio- chemical interactions of the CCM proteins). Furthering the pursuit of genetic interac...

Ngày tải lên: 15/03/2014, 10:20

... detection of microbial antigens in the synovial tissues by immunohistological staining. Conclusions Genetically defined cytokine production in the joint defines the severity of reactive arthritis by ... in the joint defines the severity of ReA by dictating the local clearance of the patho- gen. This interplay can be dramatically altered by heavy metal exposure, whi...

Ngày tải lên: 09/08/2014, 01:22

Ngày tải lên: 09/08/2014, 07:20

... patients in the Japanese was not observed. Further studies in other ethnic groups are necessary to draw definite conclusions. Competing interests The authors declare that they have no competing interests. References 1. ... Cheresh DA: The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development. J Clin Invest 1999, 103:1...

Ngày tải lên: 09/08/2014, 10:21