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Báo cáo y học: " Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" pptx

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Báo cáo y học: "High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis." ppsx

... days. The induction of arthritis byrHMGB1 is primarily mediated by IL-1 as confirmed by the absence of arthritis in IL-1 receptor-deficient mice afterrHMGB1 administration [7]. Systemic administration ... administration of eitherneutralizing HMGB1 antigen-affinity purified polyclonal anti-bodies or the anti-inflammatory domain of HMGB1, termed the A-box protein, significantly reduced mean arthritis ... unchanged in one, and increased in three,rendering the authors’ results statistically insignificant. HMGB1mRNA expression remained unchanged after infliximab therapyas indicated by only two of the...
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Báo cáo y học:

Báo cáo y học: "Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" potx

... interferon-inducible gene expressions in peripheral blood mononuclear cells in vitro The expression of 15 IFI genes (IFIT1, IFIT3, IFIT5, IFI6, IFI16,IFI27, IFI30, IFI35, interferon-induced transmembrane ... of Figure 3Effect of TNF stimulation on gene expression in healthy individuals and systemic lupus erythematosus patientsEffect of TNF stimulation on gene expression in healthy individuals and ... Abnormal expression of the genes involved in cytokine networks and mitochondrialfunction in systemic juvenile idiopathic arthritis identified byDNA maicroarray analysis. Ann Rheum Dis 2009, 68:264-272.9....
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Báo cáo y học:

Báo cáo y học: " Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" pptx

... IL-12 in system lupus erythematosus. II: IL-12 production in vitro is correlated nega-tively with serum IL-10, positively with serum IFN-gamma and negatively with disease activity in SLE. Cytokine ... and analyzedusing bioinformatics tools. Since interactions among TNF, IFN, -estradiol (E2), and IFN may regulate the expression of interferon-inducible (IFI) genes, stimulating and co-stimulatingexperiments ... cells in vitro The expression of 15 IFI genes (IFIT1, IFIT3, IFIT5, IFI6, IFI16,IFI27, IFI30, IFI35, interferon-induced transmembrane protein1, ISG15, IRF7, OAS1, OASL, GBP1, and GBP2) in PBMCsupon...
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Báo cáo y học: "Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases" ppt

... because the sensitivity of in situ hybridization is lim-ited [50]. In the previous study, the synovial lining cells of RApatients were stained by the anti-IL-32 antibody [16]. Weassumed that the ... syn-ovial lining cells by in situ hybridization in our study. Anotherexplanation is the difference of types of RA. The distribution of IL-32 expression in synovial tissues may be dependent on the type ... chondrocytes of the joints. There would there-fore be no initiation of inflammation in the joints without the infiltration of bone-marrow-derived cells expressing hIL-32. The source of IL-32 remains...
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Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx

Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx

... the 310helix, stabilized by stacking interac-tions of the pyrrolidine ring of Pro7 with the aromaticside chain of Tyr137. Modelling of the PRD1-superpeptide, which included two amino acid ... employ a well-conserved modular arrangement of interaction domains in the regulation of kinaseKeywordskinase activity; proline-rich motifs; protein–protein interactions; SH3 domain; tyrosinephosphorylationCorrespondenceT. ... performed by the Src family kinase Fyn, which docksonto PAG using a dual-domain binding mode involving both SH3- and SH2-domains of Fyn. In this study, we investigated Fyn SH3-domain bind-ing to...
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Báo cáo Y học: A complex fruit-specific type-2 ribosome-inactivating protein from elderberry (Sambucus nigra) is correctly processed and assembled in transgenic tobacco plants doc

Báo cáo Y học: A complex fruit-specific type-2 ribosome-inactivating protein from elderberry (Sambucus nigra) is correctly processed and assembled in transgenic tobacco plants doc

... molecularmodelling, which showed that all amino-acid residuesinvolved in the catalytic activity of the A-chain and the sugar-binding activity in the B-chain are identical in both type- 2 RIPs.Expression of ... concerns their specific agglutination activity and the inhibition of agglutination by lactose and fetuin. In addition, both type- 2 RIPs exhibited the same RNAN-glycosylase activity. It can be ... described previously [6]. The carbohydrate-binding specificity of the type- 2 RIPswas checked by inhibition of agglutination of trypsin-treated rabbit erythrocytes with galactose and fetuin.Therefore...
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Báo cáo y học: "Relationship among Dexamethasone Suppression Test, personality disorders and stressful life events in clinical subtypes of major depression: An exploratory study" pot

... variable, significantfindings were found concerning the endogenous axis of DMS and the HDRS depressive index. The interaction of PD and DST produced significant findings concerningage, age of onset, ... University of Thesssaloniki, Greece, 2Lab of Clin Neurophysiology, 1st Department of Neurology Aristotle University of Thesssaloniki, Greece and 3Lab of Biochemistry, Aristotle University of Thesssaloniki, ... [25]. While it is not possible tointerpret what is the cause and what is the effect, it is inter-esting that there are papers in the international literaturesuggesting that conditions of internal...
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Báo cáo y học:

Báo cáo y học: "IV among pregnant women in Moshi Tanzania: the role of sexual behavior, male partner characteristics and sexually transmitted infections" pot

... suscep-tibility by disruption of the mucosa barrier, thus provid-ing an easy port of entry and increase the recruitment and activation of HIV susceptible inflammatory cells. The inflammation and ... of International Health, Institute of General Practice and Community Medicine, University of Oslo, Norway, 2Department of Obstetric and Gynaecology, Rikshospitalet University Hospital, University ... (PMTCT) of HIV accordingto the HIVNET 012 regimen [33]. Genital infections diag-nosed during clinical examination were treated syndromi-cally based on the Tanzanian Ministry of Healthguidelines....
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Báo cáo y học:

Báo cáo y học: "Clinical Symptoms Associated with Asystolic or Bradycardic Responses on Implantable Loop Recorder Monitoring in Patients with Recurrent Syncope"

... lesions on ophthalmoscopy, with early hyopofluorescence and late staining on fluorescein angiography (FA). Inac-tive chorioretinal lesions typically are partially atro-phic and partially pigmented ... infection. In cases of severe disease, therapy is supportive, with hospitalization, intravenous fluids, respiratory sup-port, and prevention of secondary infection. Prevention is the mainstay of ... in less than 1% of patients. However, over time, WNV infection has increased in severity. The diagnosis is confirmed by detection of IgM anti-body in serum or cerebrospinal fluid.1 A typical...
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Báo cáo y học:

Báo cáo y học: "Clinical Symptoms Associated with Asystolic or Bradycardic Responses on Implantable Loop Recorder Monitoring in Patients with Recurrent Syncope"

... Patients were included in the study if they had either syncope or symptoms during monitoring which resembled the index syncope episode that lead to evaluation. Patients included in the study ... syncope of unclear etiology. The clinical symptoms of abnormalities seen during ILR monitoring have not been adequately studied. Aim: The aim of this retrospective study was to determine the clinical ... of moni-toring as well as automatic activation during events, resulting in a higher diagnostic yield than traditional monitoring techniques [6-12]. During ILR monitoring of patients with...
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