Báo cáo y học: "Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study" pptx
Báo cáo y học: "Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study" ppsx
... participated in the conception and design of the project and in the analysis and interpretation of data and contributedsubstantially to the drafting of the manuscript. VFP partici-pated in the ... notsignificant in the univariate analysis and had no impact on the frequency of the metabolic syndrome. Conclusion In summary, this study suggests that the presence of the met-abolic syndrome in RA appears ... It is therefore possible that, in RA patients, alterations in body fat/muscle may have already occurred as part of the dis-ease process and thus any additional changes that areinduced by long-term...
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Báo cáo y học: "Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study" pptx
... will have anincreased prevalence of each of the individual components of the metabolic syndrome (dyslipidaemia, hypertension, hyperg-lycaemia, and central obesity) as well as the metabolic syn-drome ... It is therefore possible that, in RA patients, alterations in body fat/muscle may have already occurred as part of the dis-ease process and thus any additional changes that areinduced by long-term ... Conversely,it may be that patients with RA have significantly modified theirrisk factors for the metabolic syndrome as a consequence of inflammation and that the addition of GC use cannot worsenthese...
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Báo cáo Y học: Chromatin assembly Cooperation between histone chaperones and ATP-dependent nucleosome remodeling machines docx
... ourunderstanding of the machinery and mechanism of chro-matin assembly. The main players in chromatin assembly that havebeen identified to date are the histone chaperones and a protein complex that ... consistent with the available data is thatactivation of Rad53 by the DNA damage checkpointreleases ASF1 into the vicinity of the DNA lesion in order tocontribute to the assembly of the newly synthesized ... DNAinto chromatin (Fig. 4B).THIS IS JUST THE BEGINNINGWe are only now gaining real insight into the machinery and mechanism of chromatin assembly. Chromatin assemblyrequires a negatively...
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Báo cáo y học: "β A randomized, controlled trial of interferon-β-1a (Avonex®) in patients with rheumatoid arthritis: a pilot study [ISRCTN03626626]" pptx
... originalURL.Abstract The objective of this study was to evaluate the safety and possible efficacy of IFN-β- 1a for the treatment of patients with rheumatoid arthritis (RA). Twenty-two patients with active ... of RA and potentially lead to a reduc-tion in symptoms and increase in function in patients with RA. The present study was designed to assess the effects of the use of IFN-β- 1a for the treatment ... has changed the paradigm of treatment options.However, despite the introduction of anti-cytokine therapy,there remains a significant unmet need for additionaltherapy in the treatment of RA...
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Báo cáo y học: "NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor" docx
... with 100 μl emulsion intrader-mally at the base of the tail. After 21 days (day 0), the sameamount of the antigen emulsified in the same adjuvant wasintradermally injected at the base of the ... byNF-κB in agreement with the in vitro studies. RANKL inducesNFATc1 expression via three intracellular signaling pathways;an NF-κB pathway, a mitogen-activated protein kinase path-way, and ... translocation and activation of NF-κB by dehydroxymethylepoxyquinomicin.J Biol Chem 2002, 277:24625-24630.15. Miyajima A, Kosaka T, Seta K, Asano T, Umezawa K, Hayakawa M:Novel nuclear factor...
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Báo cáo y học: "Rheumatoid cachexia is associated with dyslipidemia and low levels of atheroprotective natural antibodies against phosphorylcholine but not with dietary fat in patients with rheumatoid arthritis: a cross-sectional study" pdf
... statistical analysis.ResultsDietary intake and fatty acid profiles The mean dietary intake of total energy, carbohydrate, protein and fat is shown in Table 2. Compared with the Swedish FoodRecommendations ... suggesting that the increased prev-alence of coronary heart disease in RA patients may, at least in part, be attributed to inflammation and change of fat metab-olism. In the present RA population ... responsibility for analyzing the FFQ. JF was responsible for assays of lipids and anti-PC anti-bodies. TC had an active role in the design of the study, in ana-lyzing adipose tissue and an advisory role....
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Báo cáo y học: "proving draft assemblies by iterative mapping and assembly of short reads to eliminate gaps" docx
... before being incorporated back into the finalassembly. An advantage of a local assembly as opposed to a de novo one is that the number of reads used is only a fraction of total available reads. ... tospan towards the gap and manually aligned into the assembly to assess the accuracy of sequences in the closed gaps. In the second case study, the genome sequence of the rodent malaria parasite ... between the newlysequenced reads and any existing assembly by mapping, and then improves the assembly by localised assembly of reads at real gaps and regions that were previously unre-solved in the...
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Báo cáo y học: "introduction to special issue on Eye and Zoonosis – from the guest editors"
... Int. J. Med. Sci. 2009, 6 http://www.medsci.org 117American Journal of Ophthalmology: Delair E, Monnet D, Grabar S, Dupouy-Camet J, Yera H, Brézin AP. Respective roles of acquired and ... con-genital infections in presumed ocular toxoplas-mosis. Am J Ophthalmol 2008;146:851-5). • Optical Coherence Tomography in ocular toxoplasmosis • Usefulness of vitrectomy in the treatment of ... ocular toxoplasmosis • Update on the treatment of ocular toxoplasmo-sis. We hope that this special issue will be interesting to readers and provides researchers with timely up-date on various...
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Báo cáo y học: "Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor κB-dependent pathway in patients with rheumatoid arthritis" ppt
... mostlikely that the NF-κB pathway is also actively involved in the induction of IL-17 in RA PBMC. In contrast, the AP-1 signaltransduction pathway, another important signaling pathwayfor cytokines/chemokines, ... min. In contrast, non-phosphorylated Akt and β-actin remained unchanged regardless of incubation time.PHA, concanavalin A and IL-15 also demonstrated the same effect on phosphorylated Akt as ... production in PBMC from patients with RA, patients with OA and normal individualsPBMC were separated and cultured with PHA (5 µg/ml)from patients with RA, patients with OA, and age-matchednormal...
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Báo cáo y học: "Dermatological conditions during TNF-α-blocking therapy in patients with rheumatoid arthritis: a prospective study" pps
... have been reported in clinical trials,including urticaria, rash, and stomatitis (during infliximab ther-apy) [8]; rash and injection-site reactions (during adalimumabtherapy) [3,9]; and injection-site ... resolved.Hospitalization was necessary for treatment of eczema in onepatient. In another patient the eczematous lesions recurredafter adalimumab therapy was restarted. Adalimumab wascontinued and topical ... biological agents such as TNF-α-blockingagents has dramatically changed the therapeutic approach torheumatic diseases in recent years. TNF-α-blocking therapyhas had a remarkable effect on disease...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngThơ nôm tứ tuyệt trào phúng hồ xuân hươngChuong 2 nhận dạng rui roBT Tieng anh 6 UNIT 2Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ